Ionotropic glutamate receptors are a type of ligand-gated ion channel that are activated by the neurotransmitter glutamate . They are widely distributed throughout the central nervous system and play a crucial role in regulating neuronal excitability . Ionotropic glutamate receptors are composed of four or five subunits arranged around a central pore, with each subunit containing three transmembrane domains and a large extracellular domain that contains the binding site for glutamate . There are three main types of ionotropic glutamate receptors: AMPA receptors, NMDA receptors, and kainate receptors .
Ionotropic glutamate receptors
- NS 3763, Antagonist of GluK1
Cas#:70553-45-6
- TCN 213, Allosteric modulator of GluN2A
Cas#:556803-08-8
- UBP 310, Antagonist of GluK1;Antagonist of GluK3
Cas#:902464-46-4
- UBP 302, Antagonist of GluK1
Cas#:745055-91-8
- (S)-(-)-5-Iodowillardiine, Agonist of GluK1
Cas#:140187-25-3