Orphan and other 7TM receptors are a group of G protein-coupled receptors (GPCRs) that are not yet fully characterized. This group includes “orphan” GPCRs where the endogenous ligand(s) is not known, and other 7TM receptors. The Class A Orphans are a subset of orphan GPCRs that have been identified by NC-IUPHAR, for which preliminary evidence for an endogenous ligand has been published, or for which there exists a potential link to a disease or disorder.
Orphan and other 7TM receptors
Leukotriene D4, Agonist of CysLT 1 receptor;Agonist of CysLT 2 receptor;Agonist of GPR17Cas#:73836-78-9(Ethanol)
Starting at $1,030.90
Resveratrol, Inhibitor of COX-2;Agonist of TAS2R14;Antagonist of Peroxisome proliferator-activated receptor-γCas#:501-36-0
Starting at $90.90
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- NPS-2143, Allosteric modulator of CaS receptor;Allosteric modulator of GPRC6 receptor;Allosteric modulator of mGlu 5 receptor
Cas#:284035-33-2
Starting at $58.90
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