3-Carene - ≥90%(GC) , CAS No.13466-78-9

CAS: 13466-78-9 Cat. No.: C153246 Molecular Weight: 136.24 EC Number: 236-719-3
AVAILABLE TO ORDER
GRADE & PURITY ≥90%(GC)
Synonyms
(+/-)-3-CARENE | HY-N6663 | 3-Carene, >=90% | (1S)-(+)-3-Carene | EN300-173315 | 3-Carene | 4,7,7-trimethylbicyclo[4.1.0]hept-3-ene | UNII-H2M15SNR6N | CAS-13466-78-9 | E77192 | EINECS 236-719-3 | Bicyclo[4.1.0]hept-3-ene, 3,7,7-trimethyl- | Delta-3-Caren
Storage
Argon charged,Room temperature
Shipped In
Normal
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Size
Status
Price
Qty
1ml
C153246-1ml
3
$9.90
5ml
C153246-5ml
≥10
$12.90
25ml
C153246-25ml
1
$28.90
100ml
C153246-100ml
2
$55.90
500ml
C153246-500ml
2
$101.90
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Why this grade

≥90%(GC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Argon charged,Room temperature Ships Normal Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 21 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

3-Carene is a volatile monoterpene compound typically found in essential oils such as turpentine oil, juniper oil and pine needle oil. 3-Carene inhibits nociceptive stimulus-induced inflammatory infiltrates and COX-2 overexpression, and with antinociceptive effect. 3-Carene stimulates the activity and expression of alkaline phosphatase that is an early phase marker of osteoblastic differentiation.

Specifications

Synonyms
(+/-)-3-CARENE | HY-N6663 | 3-Carene, >=90% | (1S)-(+)-3-Carene | EN300-173315 | 3-Carene | 4, 7, 7-trimethylbicyclo[4.1.0]hept-3-ene | UNII-H2M15SNR6N | CAS-13466-78-9 | E77192 | EINECS 236-719-3 | Bicyclo[4.1.0]hept-3-ene, 3, 7, 7-trimethyl- | Delta-3-Caren
Specifications & Purity
≥90%(GC)
Storage
Argon charged, Room temperature
Shipped In
Normal
Action Type
INHIBITOR
Purity
≥90%(GC)
Names and Identifiers
Pubchem Sid488182994
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488182994
Canonical SmilesCC1=CCC2C(C1)C2(C)C
IUPAC Name3,7,7-trimethylbicyclo[4.1.0]hept-3-ene
InChIKeyBQOFWKZOCNGFEC-UHFFFAOYSA-N
INCHI1S/C10H16/c1-7-4-5-8-9(6-7)10(8,2)3/h4,8-9H,5-6H2,1-3H3
Isomeric SMILES CC1=CCC2C(C1)C2(C)C
WGK Germany 2
RTECS FH8400000
UN Number 2319
Packing Group III
Molecular Weight 136.24
Reaxy-Rn 8141645
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=8141645&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassLipids and lipid-like molecules
ClassPrenol lipids
SubclassMonoterpenoids
Intermediate Tree Nodes Not available
Direct ParentBicyclic monoterpenoids
Alternative Parents Polycyclic hydrocarbons  Branched unsaturated hydrocarbons  Cyclic olefins  Unsaturated aliphatic hydrocarbons  
Molecular FrameworkAliphatic homopolycyclic compounds
Substituents Carane monoterpenoid - Bicyclic monoterpenoid - Branched unsaturated hydrocarbon - Polycyclic hydrocarbon - Cyclic olefin - Unsaturated aliphatic hydrocarbon - Unsaturated hydrocarbon - Olefin - Hydrocarbon - Aliphatic homopolycyclic compound
DescriptionThis compound belongs to the class of organic compounds known as bicyclic monoterpenoids. These are monoterpenoids containing exactly 2 rings, which are fused to each other.
External Descriptors a monoterpenoid
3D Structure
Interactive Chemical Structure Model





Associated Targets(non-human)
Cutibacterium acnes (887 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Leptinotarsa decemlineata (1161 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

18 results found

Lot NumberCertificate TypeDateItem
K2116012Certificate of AnalysisAug 11, 2025 C153246
H2513481Certificate of AnalysisAug 05, 2025 C153246
H2513480Certificate of AnalysisAug 05, 2025 C153246
H2513479Certificate of AnalysisAug 05, 2025 C153246
B2625153Certificate of AnalysisAug 05, 2025 C153246
F2129221Certificate of AnalysisApr 02, 2025 C153246
F2129220Certificate of AnalysisApr 02, 2025 C153246
C2126193Certificate of AnalysisJan 10, 2025 C153246
G2416004Certificate of AnalysisMay 09, 2024 C153246
B2303156Certificate of AnalysisDec 17, 2022 C153246
D2418114Certificate of AnalysisDec 17, 2022 C153246
B2303155Certificate of AnalysisDec 17, 2022 C153246
B2303153Certificate of AnalysisDec 17, 2022 C153246
B2303151Certificate of AnalysisDec 17, 2022 C153246
B2303084Certificate of AnalysisDec 17, 2022 C153246
B2303082Certificate of AnalysisDec 17, 2022 C153246
A2419272Certificate of AnalysisOct 13, 2022 C153246
A2419273Certificate of AnalysisOct 13, 2022 C153246

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Chemical and Physical Properties
SolubilitySoluble in Ethanol,Acetone,Benzene
SensitivityAir and moisture sensitive
Refractive Index1.472
Specific Rotation[α]+15°, neat
Flash Point(°F)116.6 °F
Flash Point(°C)47 °C
Boil Point(°C)168-169°C
Molecular Weight136.230 g/mol
XLogP32.800
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count0
Rotatable Bond Count0
Exact Mass136.125 Da
Monoisotopic Mass136.125 Da
Topological Polar Surface Area0.000 Ų
Heavy Atom Count10
Formal Charge0
Complexity186.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count2
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
References
1. Yajian Wu, Runhu Xin, Miao Liang, Zhimin Zhang, Wei Guan, Rui Wang, Yuping Liu.  (2023)  Investigation on the changes of odor-active compounds of Amomum tsao-ko during natural drying.  JOURNAL OF FOOD COMPOSITION AND ANALYSIS,      [PMID:] [10.1016/j.jfca.2023.105432]
2. Yujiao Cheng, Leng Han, Linhua Huang, Xiang Tan, Houjiu Wu, Guijie Li.  (2023)  Association between flavor composition and sensory profile in thermally processed mandarin juices by multidimensional gas chromatography and multivariate statistical analysis.  FOOD CHEMISTRY,      [PMID:37030207] [10.1016/j.foodchem.2023.136026]
3. Miao Liang, Zhimin Zhang, Yajian Wu, Rui Wang, Yuping Liu.  (2022)  Comparison of Amomum tsaoko crevost et Lemaire from four regions via headspace solid-phase microextraction: Variable optimization and volatile characterization.  INDUSTRIAL CROPS AND PRODUCTS,      [PMID:] [10.1016/j.indcrop.2022.115924]
4. Ping Yang, Haili Wang, Qingqing Cao, Huanlu Song, Yongquan Xu, Yanping Lin.  (2022)  Aroma-active compounds related to Maillard reaction during roasting in Wuyi Rock tea.  JOURNAL OF FOOD COMPOSITION AND ANALYSIS,      [PMID:] [10.1016/j.jfca.2022.104954]
5. Chengyu Zheng, Qin'an Zhou, Wenqing Shao, Jing Zhang, Jun Wang.  (2022)  Early identification of fungal leaf blight disease (Alternaria alternate) on Platycladus orientalis plants by using gas chromatography-ion mobility spectrometry.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2022.107505]
6. Xu Chenyi, Ma Yuandan, Tian Zhengfeng, Luo Qingyun, Zheng Tiefeng, Wang Bin, Zuo Zhaojiang.  (2021)  Monoterpene emissions and their protection effects on adult Cinnamomum camphora against high temperature.  TREES-STRUCTURE AND FUNCTION,  36  (2): (711-721).  [PMID:] [10.1007/s00468-021-02242-4]
7. Zheng Chengyu, Zhou Qinan, Wang Zhenhe, Wang Jun.  (2021)  Behavioral responses of Platycladus orientalis plant volatiles to Phloeosinus aubei by GC-MS and HS-GC-IMS for discrimination of different invasive severity.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  413  (23): (5789-5798).  [PMID:34322736] [10.1007/s00216-021-03556-5]
8. Zhengfeng Tian, Qingyun Luo, Zhaojiang Zuo.  (2021)  Seasonal emission of monoterpenes from four chemotypes of Cinnamomum camphora.  INDUSTRIAL CROPS AND PRODUCTS,      [PMID:] [10.1016/j.indcrop.2021.113327]
9. Chengyu Zheng, Zhenhe Wang, Jing Zhang, Jun Wang, Jianli Zhong, Yongwei Wang.  (2020)  Discrimination of wood-boring beetles infested Platycladus orientalis plants by using gas chromatography-ion mobility spectrometry.  COMPUTERS AND ELECTRONICS IN AGRICULTURE,      [PMID:] [10.1016/j.compag.2020.105896]
10. Zhenhe Wang, Wei Chen, Shuang Gu, Jun Wang, Yongwei Wang.  (2020)  Discrimination of wood borers infested Platycladus orientalis trunks using quartz crystal microbalance gas sensor array.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2020.127767]
11. Wang Huatang, Chen Huiling, Wang Zhengbing, Liu Jiali, Zhang Xingyan, Li Chaofeng, Zeng Xinnian.  (2018)  Molecular Identification, Expression, and Functional Analysis of a General Odorant-Binding Protein 1 of Asian Citrus Psyllid.  ENVIRONMENTAL ENTOMOLOGY,  48  (1): (245-252).  [PMID:30566599] [10.1093/ee/nvy179]
12. Miao Liang, Runhu Xin, Wei Guan, Yuping Liu.  (2024)  Effect of moisture loss on aroma profile, key odorants, and fatty acids of Amomum tsaoko during vacuum oven drying.  FOOD CHEMISTRY,      [PMID:39674017] [10.1016/j.foodchem.2024.142421]
13. Zhiheng You, Mingming Zhao, Huizi Lu, Huayun Chen, Yixian Wang.  (2024)  Eye-Readable and Wearable Colorimetric Sensor Arrays for In Situ Monitoring of Volatile Organic Compounds.  ACS Applied Materials & Interfaces,      [PMID:38568140] [10.1021/acsami.4c00312]
14. Mingming Zhao, Zhiheng You, Huayun Chen, Xiao Wang, Yibin Ying, Yixian Wang.  (2024)  Integrated Fruit Ripeness Assessment System Based on an Artificial Olfactory Sensor and Deep Learning.  Foods,  13  (5): (793).  [PMID:38472906] [10.3390/foods13050793]
15. Yujiao Cheng, Min Zhang, Leng Han, Guijie Li, Min Hong, Hua Wang, Houjiu Wu, Linhua Huang.  (2025)  Investigating the influence of insoluble pulp particles on flavor retention and characterization of freshly squeezed and pasteurized mandarin juice.  FOOD RESEARCH INTERNATIONAL,      [PMID:40263853] [10.1016/j.foodres.2025.116237]
16. Mingming Zhao, Huizi Lu, Zhiheng You, Huayun Chen, Xiao Wang, Yaqing Zhang, Yixian Wang.  (2024)  Olfactory Visualization Sensing Array Made with CelluMOFs to Predict Fruit Ripeness Using Deep Learning.  ACS Applied Materials & Interfaces,      [PMID:39403818] [10.1021/acsami.4c09402]
17. Li Zhang, Hui Wu, Xiaoyuan Li, Xiu Zhang, Hua Li, Huaqiao Tang, Daxuan Tang, Shijing Du, Ya’’ou Liu, Yangfan Tang, Xiaoming Bao, Guoqiang Cheng.  (2025)  Screening bioactive compounds from Qianghuo (Notopterygium incisum) volatile oil via COX-2 magnetic ligand fishing.  FITOTERAPIA,      [PMID:39955008] [10.1016/j.fitote.2025.106432]
18. Siye Zhou, Jiayun Li, Dongping Chen, Zhixuan Xu, Kudousi Kuerban, Qiang Liu, Muhammad Irfan Waris, Wenwu Wu, Nannan Lv, Jianting Fan.  (2025)  Synergistic effect of β-ocimene on Hyphantria cunea sex pheromone and its potential attraction mechanism related to Ca2+ stimulation.  PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY,      [PMID:40015902] [10.1016/j.pestbp.2025.106310]
19. Xulian Song, Xiaoxiao Lin, Yu Xia, Ziji Ma, Liqin Jin, Weijun Zhang, Zhandong Wang, Christa Fittschen, Xiaofeng Tang.  (2025)  Product and mechanistic insights into the ozonolysis of Δ3-Carene.  ATMOSPHERIC ENVIRONMENT,      [PMID:] [10.1016/j.atmosenv.2025.121449]
20. Bin Liu, Jinrui Zhu, Xiaoman Ning.  (2025)  Transcriptional Response of ABCH Transporter Genes to Host Allelochemicals in Dendroctonus armandi and Their Functional Analysis.  Insects,  16  (11): (1075).  [PMID:41302821] [10.3390/insects16111075]
21. Ya Zhao, Chong Wang, Yingqi Zhao, Yufeng Shao, Hua Xie, Jiayue Yang, Weiqing Zhang, Guorong Wu, Gang Li, Ling Jiang, Xueming Yang.  (2025)  Anthropogenic effects on Δ3-carene photooxidation: Different oxidants induce significant changes of secondary organic aerosol formation mechanisms.  ATMOSPHERIC ENVIRONMENT,      [PMID:] [10.1016/j.atmosenv.2025.121313]
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