Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 8 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
4-Hydroxycoumarin is an orally activecoumarin derivative, one of the most versatile heterocyclic scaffolds, often used in the synthesis of various organic compounds. 4-Hydroxycoumarin possesses both electrophilic and nucleophilic properties. 4-Hydroxycoumarin is an HIV protease inhibitor and tyrosine kinase inhibitor. 4-Hydroxycoumarin has anti-inflammatory, antibacterial and anti-tumor effects .
| Isomeric SMILES | C1=CC=C2C(=C1)C(=CC(=O)O2)O |
|---|---|
| WGK Germany | 3 |
| RTECS | DJ3100000 |
| Alternate CAS | 22105-09-5,1076-38-6 |
| NSC Number | 11889 |
| MeSH Entry Terms | 4-hydroxycoumarin;4-OH coumarin |
| Molecular Weight | 162.14 |
| Beilstein | 17488 |
| Reaxy-Rn | 129768 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=129768&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Melt Point(°C) | 213℃ |
|---|
| 1. Jiaxiang Liu, Yanan Guo, Qian Zhang, Huizhe Niu, Da Li, Zhenhao Xu, Wentao Li, Yuzhen Zhao, Zongcheng Miao. (2025) Circularly polarized yellow luminescence using novel chiral binary coumarin-based Dy3+ complexes. DYES AND PIGMENTS, [PMID:] [10.1016/j.dyepig.2025.113156] |
| 2. Kuang Yi, Xia Yunlong, Wang Xing, Rao Qingqing, Yang Shengxiang. (2022) Magnetic Surface Molecularly Imprinted Polymer for Selective Adsorption of 4-Hydroxycoumarin. Frontiers in Chemistry, [PMID:35464201] [10.3389/fchem.2022.862777] |
| 3. Yunchang Fan, Dongxu Cai, Xin Wang, Lei Yang. (2018) Ionic Liquids: Efficient Media for the Lipase-Catalyzed Michael Addition. MOLECULES, 23 (9): (2154). [PMID:30150588] [10.3390/molecules23092154] |
| 4. Yusheng Yuan, Liu Yang, Shaopu Liu, Jidong Yang, Hui Zhang, Jingjing Yan, Xiaoli Hu. (2017) Enzyme-catalyzed Michael addition for the synthesis of warfarin and its determination via fluorescence quenching of l-tryptophan. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:28095360] [10.1016/j.saa.2017.01.014] |
| 5. Bang-Hua Xie, Zhi Guan, Yan-Hong He. (2012) Promiscuous enzyme-catalyzed Michael addition: synthesis of warfarin and derivatives. JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, 87 (12): (1709-1714). [PMID:] [10.1002/jctb.3830] |
| 6. Ruiling Zhuo, Xiaokang Zhang, Yong Chen, Mengyang Xing, Shiping Tian, Boqiang Li. (2024) 3-hydroxycoumarin effectively inhibits development and pathogenicity by targeting Pempk proteins of Penicillium expansum. POSTHARVEST BIOLOGY AND TECHNOLOGY, [PMID:] [10.1016/j.postharvbio.2024.112987] |
| 7. Jiaxiang Liu, Wenqi Song, Huizhe Niu, Ying Lu, Haiyan Yang, Wentao Li, Yu-zhen Zhao, Zongcheng Miao. (2024) Superior Circularly Polarized Luminescence Brightness Achieved with Chiral Heteroleptic Nine-Coordinate Coumarin-Based Tb3+ Complexes. INORGANIC CHEMISTRY, [PMID:39270127] [10.1021/acs.inorgchem.4c02007] |
| 8. Si-Yue Ma, Lin-Li Yang, Jing-Sha Yang, Ya Xiao, Guo-Qing Wang, Hong-Wu Liu, Yue Ding, Xiang Zhou, Li-Wei Liu, Zhi-Bing Wu, Song Yang. (2025) New coumarin–cinnamic acid hybrids: potent FtsZ inhibitors as alternatives to bactericides for controlling bacterial infection. PEST MANAGEMENT SCIENCE, [PMID:41034602] [10.1002/ps.70272] |
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