(±)5-HETE - Moligand™, ≥95%, 100 µg/ml in ethanol , CAS No.71030-39-2

CAS: 71030-39-2 Cat. No.: H336046 Molecular Weight: 320.5

GRADE & PURITY Moligand™, ≥95%, 100 µg/ml in ethanol

Synonyms

SCHEMBL44451 | SR-01000946911 | (6E,8Z,11Z,14Z)-5-hydroxy-6,8,11,14-eicosatetraenoicacid | 1-Ethyl-1,2-hydro-6-hydroxy-4-methyl-2-oxo-3-pyridinecarbonitrile | 5-Hete | 5-Hete, (+/-)- | BDBM50024447 | (??)5-HETE | HETE-5(S) | UNII-92JQY74TBX | 5-hydroxy-6E

Storage

Protected from light,Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

(±)5-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid, and it is a racemic mixture. It induces the aggregation of isolated neutrophils with an IC|50|value of 200 nM.

Specifications

Synonyms

SCHEMBL44451 | SR-01000946911 | (6E, 8Z, 11Z, 14Z)-5-hydroxy-6, 8, 11, 14-eicosatetraenoicacid | 1-Ethyl-1, 2-hydro-6-hydroxy-4-methyl-2-oxo-3-pyridinecarbonitrile | 5-Hete | 5-Hete, (+/-)- | BDBM50024447 | (??)5-HETE | HETE-5(S) | UNII-92JQY74TBX | 5-hydroxy-6E

Specifications & Purity

Moligand™, ≥95%, 100 µg/ml in ethanol

Storage

Protected from light, Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Purity

≥95%

Names and Identifiers

• Alternate CAS: 73307-52-5
• Molecular Weight: 320.5

Associated Targets(Human)

ALOX5 Tclin Arachidonate 5-lipoxygenase (6568 Activities)

Discover Target: ALOX5

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Chemical and Physical Properties

• Solubility: Soluble in water (0.8 mg/ml at 25° C), DMSO (~50 mg/ml), DMF (~50 mg/ml), ethanol, and PBS(pH7.2).
• Sensitivity: air & light sensitive
• Molecular Weight: 320.500 g/mol
• XLogP3: 5.200
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 14
• Exact Mass: 320.235 Da
• Monoisotopic Mass: 320.235 Da
• Topological Polar Surface Area: 57.500 Ų
• Heavy Atom Count: 23
• Formal Charge: 0
• Complexity: 392.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 4
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 4
• Covalently-Bonded Unit Count: 1

References

1. FengShengyong , MaEnhao , NaXiaona , WangZongmei , TaiWanbo , BaoXinhui , WangMao , ChangHan , WuBaolei , LiuMiaoxi , LiJuzhen , ShiHuicheng , YangCeli , XiMenglu , YangHaibing , LiYuhan , ZhuYibin , WangPenghua , ZhaoLing , ZhaoAi , ChengGong.  (2025)  Dietary supplementation of arachidonic acid promotes humoral immunity.  EMBO Molecular Medicine,      [PMID:40940568] [10.1038/s44321-025-00310-7]