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· · COA & SDS available for every product · Same-day shipping on in-stock items Home Bioactive Small Molecules By Signaling Pathways TGF-beta/Smad TGF-β Receptor BMS-986260 - Moligand™, ≥98% , Inhibitor of activin A receptor type 1;Inhibitor of activin A receptor type 1B;Inhibitor of transforming growth factor beta receptor 1, CAS No.2001559-19-7, Inhibitor of activin A receptor type 1;Inhibitor of activin A receptor type 1B;Inhibitor of transforming growth factor beta receptor 1 BMS-986260 - Moligand™, ≥98% , Inhibitor of activin A receptor type 1;Inhibitor of activin A receptor type 1B;Inhibitor of transforming growth factor beta receptor 1, CAS No.2001559-19-7, Inhibitor of activin A receptor type 1;Inhibitor of activin A receptor type 1B;Inhibitor of transforming growth factor beta receptor 1
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98% Synonyms
BMS986260 | BMS-986260 | GTPL10662 | EX-A7758 | AKOS040759507 | 2001559-19-7 | HY-W107024 | SCHEMBL18041543 | AT27405 | Example 32' [WO2016140884A1] | compound 10 [Velaparthi et al., 2020] | 6-(4-(3-Chloro-4-fluorophenyl)-1-(2-hydroxyethyl)-1H-imidazol-5-
Shipped In
Ice chest + Ice pads
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Why this grade Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview Information
BMS-986260 is a potent, selective, and orally bioavailable inhibitor of TGFβR1 with IC50 of 1.6 nM.
Specifications Synonyms
BMS986260 | BMS-986260 | GTPL10662 | EX-A7758 | AKOS040759507 | 2001559-19-7 | HY-W107024 | SCHEMBL18041543 | AT27405 | Example 32' [WO2016140884A1] | compound 10 [Velaparthi et al., 2020] | 6-(4-(3-Chloro-4-fluorophenyl)-1-(2-hydroxyethyl)-1H-imidazol-5-
Specifications & Purity
Moligand™, ≥98%
Biochemical and Physiological Mechanisms
BMS-986260 is a potent, selective, and orally bioavailable inhibitor of TGFβR1 with IC50 of 1.6 nM.
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Mechanism of action
Inhibitor of activin A receptor type 1;Inhibitor of activin A receptor type 1B;Inhibitor of transforming growth factor beta receptor 1
Names and Identifiers Pubchem Sid 528763489 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/528763489 Canonical Smiles C1=CC(=C(C=C1C2=C(N(C=N2)CCO)C3=NN4C(=NC=C4C#N)C=C3)Cl)F IUPAC Name 6-[5-(3-chloro-4-fluorophenyl)-3-(2-hydroxyethyl)imidazol-4-yl]imidazo[1,2-b]pyridazine-3-carbonitrile InChIKey VZZBCNXVZFAIQX-UHFFFAOYSA-N INCHI 1S/C18H12ClFN6O/c19-13-7-11(1-2-14(13)20)17-18(25(5-6-27)10-23-17)15-3-4-16-22-9-12(8-21)26(16)24-15/h1-4,7,9-10,27H,5-6H2 Isomeric SMILES C1=CC(=C(C=C1C2=C(N(C=N2)CCO)C3=NN4C(=NC=C4C#N)C=C3)Cl)F Alternate CAS 2001559-19-7 Molecular Weight 382.8 Reaxy-Rn 30323016 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=30323016&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Class Azoles Subclass Imidazoles Intermediate Tree Nodes Substituted imidazoles Direct Parent Phenylimidazoles Alternative Parents Fluorobenzenes Chlorobenzenes Pyridazines and derivatives N-substituted imidazoles Aryl fluorides Aryl chlorides Heteroaromatic compounds Nitriles Azacyclic compounds Alkanolamines Primary alcohols Organopnictogen compounds Organofluorides Organochlorides Hydrocarbon derivatives Molecular Framework Aromatic heteropolycyclic compounds Substituents 4-phenylimidazole - 5-phenylimidazole - Halobenzene - Fluorobenzene - Chlorobenzene - Benzenoid - Pyridazine - N-substituted imidazole - Monocyclic benzene moiety - Aryl halide - Aryl fluoride - Aryl chloride - Heteroaromatic compound - Azacycle - Nitrile - Carbonitrile - Alkanolamine - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Hydrocarbon derivative - Primary alcohol - Organooxygen compound - Organonitrogen compound - Organofluoride - Organochloride - Organohalogen compound - Alcohol - Aromatic heteropolycyclic compound Description This compound belongs to the class of organic compounds known as phenylimidazoles. These are polycyclic aromatic compounds containing a benzene ring linked to an imidazole ring through a CC or CN bond. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Molecular Weight 382.800 g/mol XLogP3 1.800 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 6 Rotatable Bond Count 4 Exact Mass 382.075 Da Monoisotopic Mass 382.075 Da Topological Polar Surface Area 92.000 Ų Heavy Atom Count 27 Formal Charge 0 Complexity 575.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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