Immune Checkpoints
Browse by type, application, or key specifications such as purity, grade, packaging, and handling requirements.
103 products
Popular Products
- Recombinant Human IL-2 ProteinLyophilized Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. His Tag ? His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. ≥95%(SDS-PAGE)● In Stock — US warehouse, ships to EU* Item #: rp147476View ProductPricing & Pack Sizes
Technical Identifiers
- Species
- Human
- Accession #
- P60568
- Expression system
- CHO-K1
- Protein Day
- His
- Endotoxin Concentration
- <1.0 EU/μg
- Bioactivity
- 1、Measured in a cell proliferation assay using CTLL‑2 mouse cytotoxic T cells. The ED50 for this effect is typically less than 2.5 ng/mL. 2、Measured in a cell proliferation assay using mouse splenocytes. The ED50 for this effect is typically less than 30.0 ng/mL.
- Synonyms
- IL-2 | T-cell growth factor | TCGF
- Recombinant Human TNF RII/TNFRSF1B ProteinLyophilized Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. His Tag ? His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. GST Tag ? GST tag grade — recombinant protein bearing a GST tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. ≥95%(SDS-PAGE)● In Stock — US warehouse, ships to EU* Item #: rp152522View ProductPricing & Pack Sizes
Technical Identifiers
- Species
- Human
- Accession #
- P20333
- Expression system
- E. coli
- Protein Day
- N-His & GST
- Endotoxin Concentration
- <1.0 EU/mg
- Bioactivity
- The binding activity of TNFRSF1B and TNFa, the EC50 was 0.0470~0.085 μg/ml.
- Synonyms
- CD120b antigen | CD120b | Etanercept | p75 TNF receptor | p75TBPII | p75TNFR | soluble TNFR1B variant 1 | TNF RII | T...
- Recombinant Human 4-1BB Ligand ProteinLyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. PBS Only ? PBS-only formulation — supplied in phosphate-buffered saline with no other additives. Use when you need a clean PBS buffer free of stabilizers/carriers. ≥95%(SDS-PAGE)● In Stock — US warehouse, ships to EU* Item #: rp142386View ProductPricing & Pack Sizes
Technical Identifiers
- Species
- Human
- Accession #
- P41273
- Expression system
- E. coli
- Protein Day
- No tag
- Endotoxin Concentration
- <1.0 EU/μg
- Bioactivity
- Fully biologically active when compared to standard. The ED50 as determined by stimulation of IL-8 production using human PBMC is less than 10 ng/ml.
- Synonyms
- 41BB Ligand | 4-1BB Ligand | 4-1BBL | 4-1BB-L | CD137L | homolog of mouse 4-1BB-L | receptor 4-1BB ligand | TNFSF9 | ...
- Recombinant Human CD80 ProteinLyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. His Tag ? His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. ≥95%(SDS-PAGE)● In Stock — US warehouse, ships to EU* Item #: rp144122View ProductPricing & Pack Sizes
Technical Identifiers
- Species
- Human
- Accession #
- P33681
- Expression system
- HEK293
- Protein Day
- N-His
- Endotoxin Concentration
- <1.0 EU/μg
- Bioactivity
- Measured by its binding activity of recombinant human CD80 and recombinant human CD86. The EC50 for this effect is less than 0.412μg/mL.
- Synonyms
- Activation B7-1 antigen | B7 | BB1 | CTLA-4 counter-receptor B7.1
- Recombinant Human Nectin-3 ProteinLyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. His Tag ? His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. ≥98%(SDS-PAGE)● In Stock — US warehouse, ships to EU* Item #: rp149161View ProductPricing & Pack Sizes
Technical Identifiers
- Species
- Human
- Accession #
- Q9NQS3
- Expression system
- HEK293
- Protein Day
- C-His
- Endotoxin Concentration
- <1.0 EU/μg
- Bioactivity
- Recombinant Human Nectin-3 Protein is a human protein of the immunoglobulin superfamily which forms part of adherens junctions. Human PVRL1/NECTIN1 hFc has been identified as an interactor of Nectin-3, thus a binding ELISA assay was conducted to detect the interaction of recombinant human Nectin-3 and recombinant PVRL1/NECTIN1 hFc.
- Synonyms
- CDw113 | Nectin cell adhesion molecule 3 | Poliovirus receptor-related protein 3
- Recombinant Mouse IL-2 ProteinLyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. His Tag ? His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. ≥98%(SDS-PAGE)● In Stock — US warehouse, ships to EU* Item #: rp154174View ProductPricing & Pack Sizes
Technical Identifiers
- Species
- Mouse
- Accession #
- P04351
- Expression system
- HEK293
- Protein Day
- N-His
- Endotoxin Concentration
- <1.0 EU/μg
- Bioactivity
- Recombinant Mouse IL-2 stimulates cell proliferation of the CTLL-2 mouse cytotoxic T cell line. The ED50 for this effect is typically less than 2.5 ng/mL.
- Synonyms
- Aldesleukin | IL2 | IL-2 | IL-2lymphokine | interleukin 2 | interleukin-2 | involved in regulation of T-cell clonal e...
- Recombinant Human Nectin-2/CD112 ProteinLyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. PBS Only ? PBS-only formulation — supplied in phosphate-buffered saline with no other additives. Use when you need a clean PBS buffer free of stabilizers/carriers. ≥95%(SDS-PAGE)● In Stock — US warehouse, ships to EU* Item #: rp149154View ProductPricing & Pack Sizes
Technical Identifiers
- Species
- Human
- Accession #
- Q92692
- Expression system
- HEK293
- Protein Day
- No tag
- Endotoxin Concentration
- <1.0 EU/μg
- Bioactivity
- Recombinant Human Nectin-2/CD112 Protein is a human protein of the immunoglobulin superfamily which forms part of adherens junctions. Human DNAM-1/CD226 hFc has been identified as an interactor of Nectin-2, thus a binding ELISA assay was conducted to detect the interaction of recombinant human Nectin-2 and recombinant DNAM-1/CD226 hFc.
- Synonyms
- CD112 antigen | CD112 | Herpes virus entry mediator B | Herpesvirus entry mediator B | herpesvirus entry protein B | ...
- Recombinant Human HVEM/TNFRSF14 ProteinLyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. Fc tag ? Fc tag grade — recombinant protein bearing a Fc tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. The Fc tag aids dimerization and protein-A/G capture. ≥95%(SDS-PAGE&HPLC)● In Stock — US warehouse, ships to EU* Item #: rp152533View ProductPricing & Pack Sizes
Technical Identifiers
- Species
- Human
- Accession #
- Q92956
- Expression system
- Pichia pastoris
- Protein Day
- C-hFc
- Endotoxin Concentration
- <0.1 EU/μg
- Bioactivity
- Fully biologically active when compared to standard. The biologically active as determined by its ability to inhibit TNF-beta -mediated cytotoxicity using murine L929 cells.
- Synonyms
- ATAR | CD270 antigen | CD270 | CD40-like protein | Herpes virus entry mediator A | Herpesvirus entry mediator A | Hve...
- Recombinant Human IL-10 ProteinLyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. ≥95%(SDS-PAGE)● In Stock — US warehouse, ships to EU* Item #: rp147355View ProductPricing & Pack Sizes
Technical Identifiers
- Species
- Human
- Accession #
- P22301
- Expression system
- E. coli
- Protein Day
- No tag
- Endotoxin Concentration
- <1.0 EU/μg
- Bioactivity
- 1. Measured in a cell proliferation assay using MC/9-2 mouse mast cells. The ED₅₀ for this effect is typically 1.0 - 8.0 ng/mL. 2. Immobilized Recombinant Human IL-10 Protein (rp147355) at 2 μg/mL can bind Recombinant Rhesus IL10RA Protein (Fc Tag) the EC₅₀ for this effect is 100.0 - 300.0 ng/mL.
- Synonyms
- CSIF | CSIFMGC126450 | Cytokine synthesis inhibitory factor | GVHDS | IL10 | IL-10 | IL10A | IL-10MGC126451 | interle...
- Recombinant Human CD40 Ligand/TNFSF5 ProteinLyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. PBS Only ? PBS-only formulation — supplied in phosphate-buffered saline with no other additives. Use when you need a clean PBS buffer free of stabilizers/carriers. ≥95%(SDS-PAGE&HPLC)● In Stock — US warehouse, ships to EU* Item #: rp152636View ProductPricing & Pack Sizes
Technical Identifiers
- Species
- Human
- Accession #
- P29965
- Expression system
- E. coli
- Protein Day
- No tag
- Endotoxin Concentration
- <1.0 EU/μg
- Bioactivity
- Fully biologically active when compared to standard. The ED50 as determined by the dose-dependent stimulation of IL-8 production by human PBMC is less than 5-10 ng/ml.
- Synonyms
- CD154 antigen | CD154 | CD40 antigen ligand | CD40 Ligand | CD40L | CD40-L | CD40LG | CD40LIGM | gp39 | hCD40L | HIGM...
- Recombinant Human CD30-L ProteinLyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. His Tag ? His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. ≥95%(SDS-PAGE)● In Stock — US warehouse, ships to EU* Item #: rp143950View ProductPricing & Pack Sizes
Technical Identifiers
- Species
- Human
- Accession #
- P32971
- Expression system
- HEK293
- Protein Day
- N-His
- Endotoxin Concentration
- <0.1 EU/μg
- Bioactivity
- Measured by its ability to stimulate IL-6 secretion by HDLM human Hodgkin’s lymphoma cells. The ED50 for this effect is 8-48 ng/mL in the presence of 10 µg/mL of a cross-linking antibody, Mouse Anti-polyHistidine Monoclonal Antibody.
- Synonyms
- CD153 antigen; CD153; CD30 antigen ligand; CD30 Ligand; CD30L; CD30-L; CD30LCD30 ligand; CD30LGMGC138144; TNFSF8; tum...
- Recombinant Human B7-H2 ProteinLyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. His Tag ? His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. ≥95%(SDS-PAGE)● In Stock — US warehouse, ships to EU* Item #: rp147187View ProductPricing & Pack Sizes
Technical Identifiers
- Species
- Human
- Accession #
- O75144
- Expression system
- HEK293
- Protein Day
- C-His
- Endotoxin Concentration
- <0.01 EU/μg
- Bioactivity
- Immobilized Human ICOSLG at 1 μg/mL (100 μL/well) can bind Human ICOS/CD278 with a linear range of 2-15 ng/mL.
- Synonyms
- B7H2 | B7-H2 | B7H2B7 homolog 2 | B7-H2B7-related protein 1 | B7RP-1 | B7RP1B7-like protein Gl50 | LICOS | CD275 anti...
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Technical Details Quality & specification info on every product page
Pack Size Options Multiple packaging sizes with pricing access from listing
R&D Use Only Products supplied for research and development use
Frequently Asked Questions
What should I consider when selecting an Immune Checkpoints product?
Define the transformation first, then narrow the Immune Checkpoints listing by reactivity, compatibility with your solvent and temperature window, and scale. Where several grades exist, the higher-purity option is usually worth it for downstream steps that are hard to purify.
What does Immune Checkpoints cover?
Immune Checkpoints is a top-level listing in our catalogue. Use the filters and search on the listing page to narrow by the attributes that matter for your work, or browse the neighbouring categories from the main navigation.
Which quality data should I check before ordering Immune Checkpoints?
Review the lot-specific Certificate of Analysis for the Immune Checkpoints product you have chosen: assay or HPLC purity, identity confirmation by NMR and MS, residual solvents where relevant, and appearance. For reactive or hygroscopic material the storage and handling notes matter as much as the purity figure. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search Immune Checkpoints by structure or CAS number?
Yes. Within Immune Checkpoints you can search by CAS number, molecular formula, or SMILES to reach exact structures and close analogs, and filter by functional group, purity grade, and pack size. For pricing, bulk quantities, or account eligibility, contact [email protected].