Metabolic Disease Targets
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196 products
Popular Products
- Hydroxocobalamin monohydrochlorideCAS: 58288-50-9 EC Number: 261-200-3 PubChem CID: 46783759 Formula: C62H89CoN13O15P · HCl Molecular Weight: 1382.82Solid ≥98%◐ .Made to order · 8–12 wks Item #: H304094View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
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- SMILES
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- InChIKey
- KEHNCSYXYMMUCO-UHFFFAOYSA-K
- InChI
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- Synonyms
- cobalt(3+);[5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] 1-[3-[(4Z,9Z,14Z)-2,13,18-tris(...
- Recombinant Mouse Leptin ProteinCAS: 181030-10-4 Formula: NALyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. PBS Only ? PBS-only formulation — supplied in phosphate-buffered saline with no other additives. Use when you need a clean PBS buffer free of stabilizers/carriers. ≥95%(SDS-PAGE)● In Stock — US warehouse, ships to EU* Item #: L329647View ProductPricing & Pack Sizes
Technical Identifiers
- Species
- Mouse
- Accession #
- Q544U0
- Expression system
- E. coli
- Protein Day
- No tag
- Endotoxin Concentration
- <1.0 EU/μg
- Bioactivity
- Immobilized Recombinant Mouse LEPR (C-10His) at 5μg/ml (100 μl/well) can bind Recombinant Mouse Leptin Biotinylated by NHS-biotin prior to testing.The ED50 of Recombinant Mouse Leptin is 1.16 ng/ml. Loaded Recombinant Mouse LEPR (C-10His) on HIS1K Biosensor, can bind Recombinant Mouse Leptin with an affinity constant of 0.196 nM as determined in BLI assay.
- Synonyms
- FLJ94114 | LEP | leptin (murine obesity homolog) | leptin (obesity homolog, mouse) | Leptin | OB | Obese protein | ob...
- LinderaneCAS: 13476-25-0 Formula: C15H16O4 Molecular Weight: 260.285Solid Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: L115734View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (1S,4E,12S,13S)-5,10-dimethyl-8,14,16-trioxatetracyclo[10.2.2.01,13.07,11]hexadeca-4,7(11),9-trien-15-one
- SMILES
- CC1=CCCC23C(O2)C(C4=C(C1)OC=C4C)OC3=O
- InChIKey
- KBMSVODXFLAQNJ-DXGHHDSJSA-N
- InChI
- 1S/C15H16O4/c1-8-4-3-5-15-13(19-15)12(18-14(15)16)11-9(2)7-17-10(11)6-8/h4,7,12-13H,3,5-6H2,1-2H3/b8-4+/t12-,13-,15-/m0/s1
- Recombinant Mouse TNF-alpha ProteinLyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. PBS Only ? PBS-only formulation — supplied in phosphate-buffered saline with no other additives. Use when you need a clean PBS buffer free of stabilizers/carriers. ≥97%(SDS-PAGE&HPLC)● In Stock — US warehouse, ships to EU* Item #: rp154759View ProductPricing & Pack Sizes
Technical Identifiers
- Species
- Mouse
- Accession #
- P06804
- Expression system
- E. coli
- Protein Day
- No tag
- Endotoxin Concentration
- <0.01 EU/μg
- Bioactivity
- Measured in a cytotoxicity assay using L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D (Catalog # A113142). The ED₅₀ for this effect is typically <0.1 ng/mL.
- Synonyms
- Recombinant Murine Tumor Necrosis Factor alpha (rMuTNF-α) | APC1 protein | Cachectin | Cachetin | DIF | TNF | TNF, mo...
- Recombinant Human TNF-alpha ProteinLiquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. ≥95%(SDS-PAGE) See COA● In Stock — US warehouse, ships to EU* Item #: rp152506View ProductPricing & Pack Sizes
Technical Identifiers
- Species
- Human
- Accession #
- P01375
- Expression system
- E. coli
- Protein Day
- No tag
- Endotoxin Concentration
- <0.1 EU/μg
- Bioactivity
- Measured in a cytotoxicity assay using L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D (Catalog # A113142). The ED₅₀ for this effect is typically <0.05 ng/mL.
- Synonyms
- APC1 protein | Cachectin | Cachetin | DIF | TNF | TNF, monocyte-derived | TNFA | TNF-A | TNFalpha | TNF-alpha | TNF-a...
- Recombinant Human IL-2 ProteinLyophilized Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. His Tag ? His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. ≥95%(SDS-PAGE)● In Stock — US warehouse, ships to EU* Item #: rp147476View ProductPricing & Pack Sizes
Technical Identifiers
- Species
- Human
- Accession #
- P60568
- Expression system
- CHO-K1
- Protein Day
- His
- Endotoxin Concentration
- <1.0 EU/μg
- Bioactivity
- 1、Measured in a cell proliferation assay using CTLL‑2 mouse cytotoxic T cells. The ED50 for this effect is typically less than 2.5 ng/mL. 2、Measured in a cell proliferation assay using mouse splenocytes. The ED50 for this effect is typically less than 30.0 ng/mL.
- Synonyms
- IL-2 | T-cell growth factor | TCGF
- Recombinant Human Leptin ProteinLyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. ≥97%(SDS-PAGE&HPLC)● In Stock — US warehouse, ships to EU* Item #: rp148245View ProductPricing & Pack Sizes
Technical Identifiers
- Species
- Human
- Accession #
- P41159
- Expression system
- E. coli
- Protein Day
- No tag
- Endotoxin Concentration
- <1.0 EU/μg
- Bioactivity
- Fully biologically active when compared to standard. The ED50 as determined by a chemotaxis bioassay using human Leptin R transfected BaF3 murine proB cells is less than 2 ng/ml, corresponding to a specific activity of > 5.0 × 105 IU/mg.
- Synonyms
- FLJ94114 | LEP | Leptin (murine obesity homolog) | Leptin (obesity homolog, mouse) | Leptin | OB | Obese protein | ob...
- Recombinant Rat TNF-alpha ProteinLyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. His Tag ? His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. ≥95%(SDS-PAGE)● In Stock — US warehouse, ships to EU* Item #: rp155241View ProductPricing & Pack Sizes
Technical Identifiers
- Species
- Rat
- Accession #
- P16599
- Expression system
- HEK293
- Protein Day
- C-His
- Endotoxin Concentration
- <0.1 EU/μg
- Bioactivity
- Measured in a cytotoxicity assay using L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D (Catalog # A113142). The EC50 for this effect is typically <5 pg/mL.
- Synonyms
- APC1 protein | Cachectin | Cachetin | RATTNF | DIF | TNF | TNF, monocyte-derived | TNFA | TNF-A | TNFalpha | TNF-alph...
- Recombinant Human Osteoprotegerin ProteinLyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. PBS Only ? PBS-only formulation — supplied in phosphate-buffered saline with no other additives. Use when you need a clean PBS buffer free of stabilizers/carriers. ≥95%(SDS-PAGE)● In Stock — US warehouse, ships to EU* Item #: rp149600View ProductPricing & Pack Sizes
Technical Identifiers
- Species
- Human
- Accession #
- O00300
- Expression system
- E. coli
- Protein Day
- No tag
- Endotoxin Concentration
- <1.0 EU/μg
- Bioactivity
- Fully biologically active when compared to standard. The ED50 as determined by neutralizing the stimulation of U937 cells is less than 10 ng/ml in the presence of 10 ng/mL soluble rHuRANKL (sRANKL).
- Synonyms
- OCIF | OCIFMGC29565 | OPG | OPGtumor necrosis factor receptor superfamily member 11B | Osteoclastogenesis inhibitory ...
- Recombinant Human IL-2 Receptor Alpha ProteinLyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. His Tag ? His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. ≥97%(SDS-PAGE)● In Stock — US warehouse, ships to EU* Item #: rp147480View ProductPricing & Pack Sizes
Technical Identifiers
- Species
- Human
- Accession #
- P01589
- Expression system
- HEK293
- Protein Day
- C-His
- Endotoxin Concentration
- <1.0 EU/μg
- Bioactivity
- 1. Measured by its ability to inhibit the IL-2-dependent proliferation of MO7e human megakaryocytic leukemic cells. The ED50 for this effect is 0.2 ‑1.2 µg/mL in the presence of 30 ng/mL of recombinant human IL-2. 2. Immobilized Recombinant Human IL-2 Protein (rp156004) at 1 μg/mL can bind biotinylated Recombinant Human IL-2 Receptor Alpha Protein (rp147480).
- Synonyms
- Interleukin 2 receptor alpha chain | CD25 | CD25 antigen | IDDM10 | IL 2 receptor alpha subunit | IL-2 receptor subun...
- Recombinant Human IL-6R ProteinLyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. His Tag ? His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. ≥90%(SDS-PAGE)● In Stock — US warehouse, ships to EU* Item #: rp147628View ProductPricing & Pack Sizes
Technical Identifiers
- Species
- Human
- Accession #
- P08887
- Expression system
- HEK293
- Protein Day
- C-His
- Endotoxin Concentration
- <1.0 EU/μg
- Bioactivity
- 1. Immobilized Recombinant Human IL-6 Protein at 2 μg/mL can bind Recombinant Human IL-6R Protein (rp147628) the EC50 is 8.0 - 24.0 ng/mL. 2. Measured by its ability to enhance the IL-6 activity on M1 mouse myeloid leukemia cells. The ED50 for this effect is typically 10.0 - 60.0 ng/mL.3. Using the Octet RED System, the affinity constant (Kd) of Recombinant Human IL-6R Protein (rp147628) bound Anti-IL6R Antibody was 0.1 nM.
- Synonyms
- CD126 | gp80 | IL-6 R alpha | IL6Q | IL6R alpha | IL-6R alpha | IL6R | IL-6R-1 | IL6RA | IL-6Ra | IL6RQ | interleukin...
- Recombinant Mouse IL-2 ProteinLyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. His Tag ? His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. ≥98%(SDS-PAGE)● In Stock — US warehouse, ships to EU* Item #: rp154174View ProductPricing & Pack Sizes
Technical Identifiers
- Species
- Mouse
- Accession #
- P04351
- Expression system
- HEK293
- Protein Day
- N-His
- Endotoxin Concentration
- <1.0 EU/μg
- Bioactivity
- Recombinant Mouse IL-2 stimulates cell proliferation of the CTLL-2 mouse cytotoxic T cell line. The ED50 for this effect is typically less than 2.5 ng/mL.
- Synonyms
- Aldesleukin | IL2 | IL-2 | IL-2lymphokine | interleukin 2 | interleukin-2 | involved in regulation of T-cell clonal e...
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R&D Use Only Products supplied for research and development use
Frequently Asked Questions
How do I choose the right Metabolic Disease Targets for my synthesis route?
Work backwards from the target structure: identify the bonds you need to form, then pick the Metabolic Disease Targets entry whose functional groups, protecting-group pattern, and stereochemistry match. Compare purity, available pack sizes, and stability under your reaction conditions before committing to a route.
What does Metabolic Disease Targets cover?
Metabolic Disease Targets is a top-level listing in our catalogue. Use the filters and search on the listing page to narrow by the attributes that matter for your work, or browse the neighbouring categories from the main navigation.
What specifications matter most for Metabolic Disease Targets?
For Metabolic Disease Targets, purity is the headline figure — 95% or better is a common floor for medicinal chemistry, and higher for late-stage steps. Also check isomeric and stereochemical purity, water content for moisture-sensitive groups, storage temperature, and that the pack size matches your scale. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the Metabolic Disease Targets I need is not listed?
Search Metabolic Disease Targets by CAS number or SMILES first — close analogs are often listed under a neighbouring subcategory. If nothing matches, custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.