Crotamiton - Moligand™, 10mM in DMSO , Inhibitor of TRPV4, CAS No.483-63-6, Inhibitor of TRPV4

CAS: 483-63-6 Cat. No.: C407741 Molecular Weight: 203.28 EC Number: 207-596-3

GRADE & PURITY Moligand™, 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Information

Crotamiton is a drug that is used as a scabicidal (for treating scabies) and an antipruritic
In vitro

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥98%

Specifications

Specifications & Purity

Moligand™, 10mM in DMSO

Biochemical and Physiological Mechanisms

Crotamiton is a drug that is used as a scabicidal (for treating scabies) and an antipruritic

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Action Type

INHIBITOR

Mechanism of action

Inhibitor of TRPV4

Product Properties

• ALogP: 2.8

Names and Identifiers

• Isomeric SMILES: CCN(C1=CC=CC=C1C)C(=O)/C=C/C
• WGK Germany: 3
• RTECS: GQ7000000
• Molecular Weight: 203.28
• Reaxy-Rn: 9759779
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=9759779&ln=

Associated Targets(Human)

TRPV4 Tchem Transient receptor potential cation channel subfamily V member 4 (0 Activities)

Discover Target: TRPV4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Chemical and Physical Properties

• Refractive Index: 1.54
• Flash Point(°F): 235.4 °F
• Flash Point(°C): 113 °C
• Boil Point(°C): 153-155°C/13mmHg

References

1. Xixi Chen, Wanyi Fu, Yulong Yang, Yanjun Li, Kai Yang, Xuanbo Xu, Xihui Zhang.  (2023)  Essential role of atomic H* in activating hydrogen peroxide to produce singlet oxygen for emerging organic contaminants degradation.  Journal of Environmental Chemical Engineering,      [PMID:] [10.1016/j.jece.2023.109442]