D-(+)-Gluconic acid δ-lactone - 10mM in DMSO , CAS No.90-80-2

CAS: 90-80-2 Cat. No.: D426861 Formula: C₆H₁₀O₆ Molecular Weight: 178.14 Beilstein Registry Number: 83286 EC Number: 202-016-5

GRADE & PURITY 10mM in DMSO

Synonyms

1,5-D-Gluconolactone | D-(+)-Gluconic acid d-lactone | D-(+)-Gluconic acid-delta lactone | EINECS 202-016-5 | D-Gluconic acid lactone | delta-Gluconic acid lactone | UNII-WQ29KQ9POT | delta-Gluconic acid-delta-lactone | NSC34393 | NSC-34393 | Glucolactone

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Product Application：

Glucono delta-lactone (GDL) is a kind of excellent multifunctional food additive. It is mainly used as protein coagulant, acidifier, pickling, or leavening agent. expander, preservative, seasonings, sequestrant, chelating agent, color-preserver, etc. it is widely applied to food, daily chemical industry, pharmaceuticals, cosmetics. Plastic and resinous modification, electrode position and polish, metal-surface cleaning and organic synthesis.

Specifications

Synonyms

1,5-D-Gluconolactone | D-(+)-Gluconic acid d-lactone | D-(+)-Gluconic acid-delta lactone | EINECS 202-016-5 | D-Gluconic acid lactone | delta-Gluconic acid lactone | UNII-WQ29KQ9POT | delta-Gluconic acid-delta-lactone | NSC34393 | NSC-34393 | Glucolactone

Specifications & Purity

10mM in DMSO

Biochemical and Physiological Mechanisms

Gluconolactone is a product of the oxidation of glucose by glucose oxidase. It has been found to be a mixed type, noncompetitive inhibitor for the hydrolysis of p-nitrophenyl alpha-D-glucoside by glucoamylase, an enzyme that breaks down starch into glucos

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

Pubchem Sid

528763989

Canonical Smiles

C(C1C(C(C(C(=O)O1)O)O)O)O

IUPAC Name

(3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-one

InChIKey

PHOQVHQSTUBQQK-SQOUGZDYSA-N

INCHI

1S/C6H10O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-5,7-10H,1H2/t2-,3-,4+,5-/m1/s1

Isomeric SMILES

C([C@@H]1[C@H]([C@@H]([C@H](C(=O)O1)O)O)O)O

WGK Germany

3

RTECS

LZ5184000

Molecular Weight

178.14

Beilstein

83286

Reaxy-Rn

13905182

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=13905182&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic oxygen compounds
    • Class Organooxygen compounds
      • Subclass Carbohydrates and carbohydrate conjugates
        • Level5 Monosaccharides
          • Level6 Hexoses
            • Level7 Gluconolactones

• Kingdom: Organic compounds
• Superclass: Organic oxygen compounds
• Class: Organooxygen compounds
• Subclass: Carbohydrates and carbohydrate conjugates
• Intermediate Tree Nodes: Monosaccharides - Hexoses
• Direct Parent: Gluconolactones
• Alternative Parents: Delta valerolactones Oxanes Secondary alcohols Carboxylic acid esters Polyols Oxacyclic compounds Monocarboxylic acids and derivatives Primary alcohols Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: Gluconolactone - Delta valerolactone - Delta_valerolactone - Oxane - Carboxylic acid ester - Lactone - Secondary alcohol - Organoheterocyclic compound - Monocarboxylic acid or derivatives - Oxacycle - Carboxylic acid derivative - Polyol - Hydrocarbon derivative - Organic oxide - Alcohol - Primary alcohol - Carbonyl group - Aliphatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as gluconolactones. These are polyhydroxy acids containing a gluconolactone molecule, which is characterized by a tetrahydropyran substituted by three hydroxyl groups, one ketone group, and one hydroxymethyl group.
• External Descriptors: aldono-1,5-lactone - gluconolactone

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

GBA1 Tclin Beta-glucocerebrosidase (14647 Activities)

Discover Target: GBA1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

LMNA Tbio Prelamin-A/C (36751 Activities)

Discover Target: LMNA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)

Discover Target: SLCO1B1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)

Discover Target: SLCO1B3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Chemical and Physical Properties

• Sensitivity: Moisture sensitive; light sensitive
• x_specific_rotation: 63.5 ° (C=10, H2O)
• x_melt_point_char: 160°C
• Molecular Weight: 178.140 g/mol
• XLogP3: -2.000
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 1
• Exact Mass: 178.048 Da
• Monoisotopic Mass: 178.048 Da
• Topological Polar Surface Area: 107.000 Ų
• Heavy Atom Count: 12
• Formal Charge: 0
• Complexity: 181.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 4
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1