D-Proline - Moligand™, ≥99% , CAS No.344-25-2

CAS: 344-25-2 Cat. No.: P111001 Formula: C₅H₉NO₂ Molecular Weight: 115.13 Beilstein Registry Number: 80811 EC Number: 206-452-7

GRADE & PURITY Moligand™, ≥99%

Synonyms

H-D-Pro-OH | (D)-proline | J-300218 | H-Pros-OH | (2R)-pyrrolidine-2-carboxylic acid | AM20090537 | L01Q4LGZ5L | PROLINE, D- | SCHEMBL65555 | (+)-(R)-PROLINE | Q20035962 | R)-2-Carboxypyrrolidine | (R)-PROLINE | D-D-Pro-OH | DTXSID70883367 | GTPL4676 | (R

Storage

Room temperature,Argon charged,Desiccated

Shipped In

Normal

Overview

Product Describtion:
D-proline is an isomer of the naturally occurring amino acid, L-Proline. D-amino acids have been found in relatively high abundance in human plasma and saliva. These amino acids may be of bacterial origin, but there is also evidence that they are endogenously produced through amino acid racemase activity.

Specifications

Synonyms

H-D-Pro-OH | (D)-proline | J-300218 | H-Pros-OH | (2R)-pyrrolidine-2-carboxylic acid | AM20090537 | L01Q4LGZ5L | PROLINE, D- | SCHEMBL65555 | (+)-(R)-PROLINE | Q20035962 | R)-2-Carboxypyrrolidine | (R)-PROLINE | D-D-Pro-OH | DTXSID70883367 | GTPL4676 | (R

Specifications & Purity

Moligand™, ≥99%

Storage

Room temperature,Argon charged,Desiccated

Shipped In

Normal

Grade

Moligand™

Purity

≥99%

Names and Identifiers

Pubchem Sid

488180918

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/488180918

Canonical Smiles

C1CC(NC1)C(=O)O

IUPAC Name

(2R)-pyrrolidine-2-carboxylic acid

InChIKey

ONIBWKKTOPOVIA-SCSAIBSYSA-N

INCHI

1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m1/s1

Isomeric SMILES

C1C[C@@H](NC1)C(=O)O

WGK Germany

3

Molecular Weight

115.13

Beilstein

80811

Reaxy-Rn

80809

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=80809&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Class Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives
            • Level7 Proline and derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Class: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives - Alpha amino acids and derivatives
• Direct Parent: Proline and derivatives
• Alternative Parents: D-alpha-amino acids Pyrrolidine carboxylic acids Amino acids Monocarboxylic acids and derivatives Dialkylamines Carboxylic acids Azacyclic compounds Organopnictogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: Proline or derivatives - Alpha-amino acid - D-alpha-amino acid - Pyrrolidine carboxylic acid - Pyrrolidine carboxylic acid or derivatives - Pyrrolidine - Amino acid - Carboxylic acid - Secondary aliphatic amine - Monocarboxylic acid or derivatives - Secondary amine - Organoheterocyclic compound - Azacycle - Organic oxygen compound - Organooxygen compound - Organonitrogen compound - Amine - Organopnictogen compound - Organic oxide - Carbonyl group - Organic nitrogen compound - Hydrocarbon derivative - Aliphatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as proline and derivatives. These are compounds containing proline or a derivative thereof resulting from reaction of proline at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom.
• External Descriptors: Other amino acids

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

GRIN1 Tclin Glutamate (NMDA) receptor subunit zeta 1 (122 Activities)

Discover Target: GRIN1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Staphylococcus aureus (210822 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ffp 4'-phosphopantetheinyl transferase ffp (24982 Activities)

Discover Target: ffp

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Chemical and Physical Properties

• Solubility: Soluble in water (1620 g/l at 20 °C), and acetone (slightly). Insoluble in ethanol.
• Sensitivity: Moisture sensitive
• x_specific_rotation: 85° (C=4,H2O)
• x_melt_point_char: 223°C
• Molecular Weight: 115.130 g/mol
• XLogP3: -2.500
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 115.063 Da
• Monoisotopic Mass: 115.063 Da
• Topological Polar Surface Area: 49.300 Ų
• Heavy Atom Count: 8
• Formal Charge: 0
• Complexity: 103.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1