DEAE-Dextran - pharmaceutical grade, PharmPure™, Mw 500000 , CAS No.9064-91-9

CAS: 9064-91-9 Cat. No.: D401042

GRADE & PURITY PharmPure™, Pharmaceutical grade, Mw 500000

Storage

Desiccated,Room temperature

Shipped In

Normal

Overview

Descriptio
DEAE-Dextran 500 Pharmaceutical Quality,Mw,500000,is a polycationic derivative of dextran, produced from dextran with an average molecular weight >500,000 Da. DEAE-Dextran 500 Pharmaceutical Quality is produced according to current GMP guidelines, suitable for use as an Active Pharmaceutical Ingredient (API) or in pharmaceutical preparations e.g. as a vaccine adjuvant, a transfection agent for gene therapy, and as an ingredient in cholesterol lowering products.

DEAE-Dextran 500 Pharmaceutical Quality is supplied in its HCI form.

Specification

Appearance                                                                                  White or almost white powder

Appearance of solution (6% sol.)                                             Clear and colourless

Loss on drying (105°C, 5h)                                                         ≤7

Absorbance at 375 nm, 6% sol., 4cm                                       ≤0.1

Specific rotation°                                                                         135-155

Nitrogen content                                                                          2.5-4.0

Lead, ppm                                                                                     ≤5

Specific viscosity                                                                         0.5-1

Residue on ignition                                                                      ≤1

Infrared Absorption                                                                    Complies

pH (1%w/v in 1M KCl)                                                                4-7

Degree of substitution                                                               0.4-0.72

Microbial contamination (TAMC)                                            ≤100

Microbial contamination (TYMC)                                            ≤100

Bacterial endotoxins                                                                  ≤10

Specifications

Specifications & Purity

pharmaceutical grade, PharmPure™, Mw 500000

Storage

Desiccated,Room temperature

Shipped In

Normal

Grade

Pharmaceutical grade, PharmPure™

Chemical and Physical Properties

• Sensitivity: Moisture sensitive