Dexmecamylamine , Neuronal acetylcholine receptor; alpha4/beta2 antagonist, CAS No.107538-05-6, Neuronal acetylcholine receptor; alpha4/beta2 antagonist

CAS: 107538-05-6 Cat. No.: D669182 Molecular Weight: 167.29 PubChem CID: 12358972
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Synonyms
DEXMECAMYLAMINE | Mecamylamine [MI] | Mecamylamine [INN] | Mecamylamine [VANDF] | Mecamylamine [WHO-DD] | (+)-Mecamylamine | 6EE945D3OK | Dexmecamylamine [USAN] | N,2,3,3-tetramethyl-2-norbornanamine | UNII-6EE945D3OK | Mecamylamine [INN:WHO-DD] | 5Y1141Y
Storage
Room temperature
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Size
Status
Price
Qty
1mg
D669182-1mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.

$571.90

$999.90
Save $428.00 (42.80%)
5mg
D669182-5mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.

$1,999.90

$2,999.90
Save $1,000.00 (33.33%)
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Why this grade

for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Room temperature Ships Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
DEXMECAMYLAMINE | Mecamylamine [MI] | Mecamylamine [INN] | Mecamylamine [VANDF] | Mecamylamine [WHO-DD] | (+)-Mecamylamine | 6EE945D3OK | Dexmecamylamine [USAN] | N, 2, 3, 3-tetramethyl-2-norbornanamine | UNII-6EE945D3OK | Mecamylamine [INN:WHO-DD] | 5Y1141Y
Storage
Room temperature
Action Type
ANTAGONIST
Mechanism of action
Neuronal acetylcholine receptor; alpha4/beta2 antagonist
Product Properties
ALogP2.6
Names and Identifiers
Canonical SmilesCC1(C2CCC(C2)C1(C)NC)C
IUPAC Name(1R,2S,4S)-N,2,3,3-tetramethylbicyclo[2.2.1]heptan-2-amine
InChIKeyIMYZQPCYWPFTAG-NGZCFLSTSA-N
INCHI1S/C11H21N/c1-10(2)8-5-6-9(7-8)11(10,3)12-4/h8-9,12H,5-7H2,1-4H3/t8-,9+,11-/m0/s1
Isomeric SMILES C[C@@]1([C@@H]2CC[C@@H](C2)C1(C)C)NC
PubChem CID 12358972
Molecular Weight 167.29

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassLipids and lipid-like molecules
ClassPrenol lipids
SubclassMonoterpenoids
Intermediate Tree Nodes Not available
Direct ParentBicyclic monoterpenoids
Alternative Parents Dialkylamines  Organopnictogen compounds  Hydrocarbon derivatives  
Molecular FrameworkAliphatic homopolycyclic compounds
Substituents Bicyclic monoterpenoid - Secondary amine - Secondary aliphatic amine - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organonitrogen compound - Amine - Aliphatic homopolycyclic compound
DescriptionThis compound belongs to the class of organic compounds known as bicyclic monoterpenoids. These are monoterpenoids containing exactly 2 rings, which are fused to each other.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
CHRNA7 Tchem Neuronal acetylcholine receptor subunit alpha-7 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CHRNA7 Tchem Neuronal acetylcholine receptor protein alpha-7 subunit (3524 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRNA1 Tclin Acetylcholine receptor; alpha1/beta1/delta/gamma (501 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRNB2 Tclin Neuronal acetylcholine receptor; alpha4/beta2 (3972 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
Molecular Weight167.290 g/mol
XLogP32.600
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count1
Rotatable Bond Count1
Exact Mass167.167 Da
Monoisotopic Mass167.167 Da
Topological Polar Surface Area12.000 Ų
Heavy Atom Count12
Formal Charge0
Complexity197.000
Isotope Atom Count0
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Solution Calculators
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