DiAzKs - ≥95% , CAS No.1253643-88-7

CAS: 1253643-88-7 Cat. No.: A288380 Molecular Weight: 272.3 EC Number: 111-903-5
AVAILABLE TO ORDER
GRADE & PURITY ≥95%
Synonyms
H-L-Photo-lysine | AbK | (2S)-2-amino-6-[2-(3-methyldiazirin-3-yl)ethoxycarbonylamino]hexanoic acid | (2S)-2-amino-6-({[2-(3-methyl-3H-diazirin-3-yl)ethoxy]carbonyl}amino)hexanoic acid
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1mg
A288380-1mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$70.90
5mg
A288380-5mg
4
$251.90
10mg
A288380-10mg
3
$395.90
25mg
A288380-25mg
2
$791.90
Enter a quantity for the sizes you want to add.
🧪

Why this grade

≥95% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Product Describtion:

DiAzKs (H-L-Photo-lysine) is a diazirine-containing lysine amino acid and is a photo-cross-linker. DiAzKs can site-selective incorporated into proteins and is used to crosslink protein-protein interactions in vitro and in living cells. DiAzKs acts as a UV light-activated photo-crosslinking probe.

Specifications

Synonyms
H-L-Photo-lysine | AbK | (2S)-2-amino-6-[2-(3-methyldiazirin-3-yl)ethoxycarbonylamino]hexanoic acid | (2S)-2-amino-6-({[2-(3-methyl-3H-diazirin-3-yl)ethoxy]carbonyl}amino)hexanoic acid
Specifications & Purity
≥95%
Biochemical and Physiological Mechanisms
Unnatural amino acid. Acts as a UV light-activated photo-crosslinking probe when incorporated into proteins by pyrrolysyl tRNA synthetase/tRNACUApairs.
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Purity
≥95%
Names and Identifiers
Pubchem Sid504771859
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504771859
Canonical SmilesCC1(N=N1)CCOC(=O)NCCCCC(C(=O)O)N
IUPAC Name(2S)-2-amino-6-[2-(3-methyldiazirin-3-yl)ethoxycarbonylamino]hexanoic acid
InChIKeyLUCMNTLJAFTFDU-QMMMGPOBSA-N
INCHI1S/C11H20N4O4/c1-11(14-15-11)5-7-19-10(18)13-6-3-2-4-8(12)9(16)17/h8H,2-7,12H2,1H3,(H,13,18)(H,16,17)/t8-/m0/s1
Isomeric SMILES CC1(N=N1)CCOC(=O)NCCCC[C@@H](C(=O)O)N
Molecular Weight 272.3
Reaxy-Rn 54891734
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=54891734&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic acids and derivatives
ClassCarboxylic acids and derivatives
SubclassAmino acids, peptides, and analogues
Intermediate Tree Nodes Amino acids and derivatives - Alpha amino acids and derivatives - Alpha amino acids
Direct ParentL-alpha-amino acids
Alternative Parents Medium-chain fatty acids  Heterocyclic fatty acids  Amino fatty acids  Carbamate esters  Amino acids  Propargyl-type 1,3-dipolar organic compounds  Monocarboxylic acids and derivatives  Diazirines  Carboxylic acids  Azacyclic compounds  Organic oxides  Monoalkylamines  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAliphatic heteromonocyclic compounds
Substituents L-alpha-amino acid - Medium-chain fatty acid - Amino fatty acid - Heterocyclic fatty acid - Fatty acid - Fatty acyl - Carbamic acid ester - Amino acid - Carboxylic acid - Diazirine - Monocarboxylic acid or derivatives - Propargyl-type 1,3-dipolar organic compound - Organic 1,3-dipolar compound - Organoheterocyclic compound - Azacycle - Organooxygen compound - Organonitrogen compound - Primary aliphatic amine - Primary amine - Organic oxygen compound - Organic nitrogen compound - Carbonyl group - Organic oxide - Hydrocarbon derivative - Amine - Aliphatic heteromonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as l-alpha-amino acids. These are alpha amino acids which have the L-configuration of the alpha-carbon atom.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

7 results found

Lot NumberCertificate TypeDateItem
E2626151Certificate of AnalysisMay 29, 2026 A288380
F2325139Certificate of AnalysisApr 02, 2026 A288380
F2325140Certificate of AnalysisApr 02, 2026 A288380
F2325141Certificate of AnalysisApr 02, 2026 A288380
F2325145Certificate of AnalysisApr 02, 2026 A288380
F2325148Certificate of AnalysisApr 02, 2026 A288380
F2325149Certificate of AnalysisApr 02, 2026 A288380
Chemical and Physical Properties
SolubilitySolvent:water, Max Conc. mg/mL: 2.72, Max Conc. mM: 10 with gentle warming; Solvent:1eq. HCl, Max Conc. mg/mL: 27.23, Max Conc. mM: 100
Sensitivitylight & heat & moisture sensitive
Molecular Weight272.300 g/mol
XLogP3-1.900
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count7
Rotatable Bond Count10
Exact Mass272.148 Da
Monoisotopic Mass272.148 Da
Topological Polar Surface Area126.000 Ų
Heavy Atom Count19
Formal Charge0
Complexity353.000
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Solution Calculators
Reviews

Customer Reviews

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.