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Endothelin 1，TFA, CAS No.117399-94-7(free)
AVAILABLE TO ORDER
GRADE & PURITY ≥95%
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Why this grade
≥95% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 1 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
Product Introduction
Soluble in water.
A 21-amino acid polypeptide with potent vasoconstrictive action. Produces convulsions, arterial hypertension, and metabolic activation of periventricular white and gray matter. Its effects are mediated via L-type Ca2+ channels. Reported to activate phospholipase C in fibroblasts expressing ETA receptors.
Biochemical mechanism
Product does not compete with ATP.
Reversible: no
Cell permeable: no
Primary Target
Potent vasoconstrictive action
Specifications
Product Name
Endothelin 1，TFA, CAS No.117399-94-7(free)
Synonyms
ET-1, CSCSSLMDKECVYFCHLDIIW
Specifications & Purity
≥95%
Sequence
Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp (Disulfide bridge: Cys1-Cys15, Cys3-Cys11)
CAS
117399-94-7(free)
Molecule Type
Peptide
Storage and Shipping
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 B2223653 | Certificate of Analysis | Dec 10, 2025 | E359015 |
| B2223654 | Certificate of Analysis | Dec 10, 2025 | E359015 |
| B2223655 | Certificate of Analysis | Dec 10, 2025 | E359015 |
| B2223662 | Certificate of Analysis | Dec 10, 2025 | E359015 |
| B2223663 | Certificate of Analysis | Dec 10, 2025 | E359015 |
| B2223664 | Certificate of Analysis | Dec 10, 2025 | E359015 |
| G2502090 | Certificate of Analysis | Feb 10, 2022 | E359015 |
Citations of This Product
References
| 1. Nashwa Amin, Shijia Chen, Qiannan Ren, Xiaoning Tan, Benson O. A. Botchway, Zhiying Hu, Fengpei Chen, Shan Ye, Xiaoxue Du, Zuobing Chen, Marong Fang. (2021) Hypoxia Inducible Factor-1α Attenuates Ischemic Brain Damage by Modulating Inflammatory Response and Glial Activity. Cells, 10 (6): (1359). [PMID:34205911] [10.3390/cells10061359] |
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