Erythromycin Ethylsuccinate - 10mM in DMSO , Bacterial 70S ribosome inhibitor, CAS No.1264-62-6, Bacterial 70S ribosome inhibitor

CAS: 1264-62-6 Cat. No.: E408903 Formula: C₄₃H₇₅NO₁₆ Molecular Weight: 862.05 EC Number: 215-033-8

GRADE & PURITY 10mM in DMSO

Synonyms

Erythromycin, 2-(ethyl butanedioate)

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Information

Erythromycin Ethylsuccinate, an oral macrolide antibiotic produced byStreptomyces erythreus, reversibly binds to the50S ribosomeof bacteria, and inhibits protein synthesis.
In vitro

Erythromycin displays antibacterial activity against Staphylococcus aureus, streptococcus pneumonia, Streptococcus pyogenes, Haemophilus influenza, Moraxella catarrhalis, Bordetella pertussis, Neisseria gonorrhoeae, Campylobacter jejuni, Helicobacter pylori, and Borrelia burgdorferi. Erythromycin is a motilin receptor agonist, which is a potent stimulator of gastrointestinal motor activity. The concentrations of Erythromycin required to induce 50% of the maximum contractile response to a supramaximal dose of acetylcholine is 2 μM. The concentrations of Erythromycin required to displace 50% of the labeled motilin is 13 μM. Erythromycin has no effect on muscle strips of rat or dog duodenum but induces contractions in human strips.

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:

Specifications

Synonyms

Erythromycin, 2-(ethyl butanedioate)

Specifications & Purity

10mM in DMSO

Biochemical and Physiological Mechanisms

Erythromycin Ethylsuccinate, an oral macrolide antibiotic produced by Streptomyces erythreus, reversibly binds to the 50S ribosome of bacteria, and inhibits protein synthesis.

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

INHIBITOR

Mechanism of action

Bacterial 70S ribosome inhibitor

Product Properties

alogp

3.4

Names and Identifiers

Isomeric SMILES

CC[C@@H]1[C@@]([C@@H]([C@H](C(=O)[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)OC(=O)CCC(=O)OCC)(C)O)C)C)O)(C)O

WGK Germany

2

RTECS

WM9800000

Molecular Weight

862.05

Reaxy-Rn

28936360

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=28936360&ln=

Frequently Asked Questions

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1264-62-6, the molecular formula is C43H75NO16, and the molecular weight is 862.05 g/mol.

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.