HEXO Mouse mAb - Primary antibody, specific to ERI1

Cat. No.: Ab107371

GRADE & PURITY See COA

Application

IHC, WB

Host species

Mouse

Reactive species

Human, Monkey, Rat

Isotype

Mouse IgG2b

Clone Number

OTI1B3

Conjugation

Unconjugated

Overview

Mouse anti Human HEXO Antibody, Monoclonal (OTI1B3), could be used for WB, IHC and so on.

Specifications

Product Name

HEXO Mouse mAb - Primary antibody, specific to ERI1

Synonyms

3' 5' exonuclease ERI 1 antibody | 3' 5' exonuclease ERI1 antibody | 3' EXO antibody | 3' exoribonuclease antibody | 3' HEXO antibody | 3' histone mRNA exonuclease 1 antibody | 3''-5'' exonuclease eri1 antibody | 3''-5'' exoribonuclease 1 antibody | 3'EXO

Specifications & Purity

See COA

Biochemical and Physiological Mechanisms

RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end is required for effic

Host species

Mouse

Specificity

ERI1

Immunogen

Recombinant full length protein of human ERI1 produced in HEK293T.

Positive Control

WB: HEK293T transfected with pCMV6-ENTRY ERI1 cDNA for 48 hrs, HepG2, HeLa, A549, COS7, Jurkat, PC12 lysates. IHC: Human Kidney, endometrium, bladder carcinoma, tonsil tissues.

Conjugation

Unconjugated

SDS-PAGE

150 kDa

Purification Method

Protein A purified

Concentration

See COA

Storage and Shipping

Shape

Liquid

Storage

Store at -20°C,Avoid repeated freezing and thawing

Shipped In

Ice chest + Ice pads

Stability And Storage

Store at 2-8℃ short term (1-2 weeks). Store at -20℃ long term (12 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Application

• Application: Dilution info
• WB:

  1/500-1/2000 ;

• IHC:

  1/150

Associated Targets(Human)

ERI1 Tbio 3'-5' exoribonuclease 1 (0 Activities)

Discover Target: ERI1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Frequently Asked Questions

How should this product be stored?

Store at ?20 °C. Avoid repeated freeze–thaw cycles. Aliquot into single-use volumes before freezing.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

Which species reactivity has this antibody been validated against?

Validated reactivity is listed on the PDP and on each lot's datasheet. We validate against the most commonly tested species for the target (HEXO Mouse mAb); cross-reactivity in untested species may exist but is not guaranteed. Contact technical support for specific species inquiries.