In Vitro:JB061 (compound 6a) (40 μM; 24 h) inhibits cytokinesis in Cos-7 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Biological Activity:JB061 is a nonmuscle myosin inhibitor with IC 50 s of 4.4 μM ( Cardiac muscle myosin ), 9.1 μM ( Skeletal muscle myosin ), and >100 μM ( Smooth muscle myosin II ), respectively. JB061 poorly decreases ATPase activity ( IC 50 >200 μM). JB061 shows cytotoxi
Specifications
Specifications & Purity
10mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
INHIBITOR
Names and Identifiers
Molecular Weight
323.34
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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