L-Thiaproline - ≥98%(HPLC) , CAS No.34592-47-7

CAS: 34592-47-7 Cat. No.: T137734 Formula: C₄H₇NO₂S Molecular Weight: 133.17 Beilstein Registry Number: 81065 EC Number: 252-106-3 PubChem CID: 93176

GRADE & PURITY ≥98%(HPLC)

Synonyms

4-Thiazolidinecarboxylic acid, (R)- | (R)-timonacic | Syrigin | TIMONACIC, (-)- | DTXSID3046536 | BDBM50357232 | L-Thioproline | Thioproline, L- | (R)-(-)-4-Thiazolidinecarboxylic acid | AKOS016346321 | Styryl carbinol | CAS-34592-47-7 | CCRIS 3646 | DTXC

Storage

Room temperature,Argon charged

Shipped In

Normal

Overview

L-4-Thiazolidinecarboxylic acid has been used in peptide coupling reactions.

Specifications

Synonyms

4-Thiazolidinecarboxylic acid, (R)- | (R)-timonacic | Syrigin | TIMONACIC, (-)- | DTXSID3046536 | BDBM50357232 | L-Thioproline | Thioproline, L- | (R)-(-)-4-Thiazolidinecarboxylic acid | AKOS016346321 | Styryl carbinol | CAS-34592-47-7 | CCRIS 3646 | DTXC

Specifications & Purity

≥98%(HPLC)

Storage

Room temperature,Argon charged

Shipped In

Normal

Purity

≥98%(HPLC)

Names and Identifiers

Pubchem Sid

504756175

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504756175

Canonical Smiles

C1C(NCS1)C(=O)O

IUPAC Name

(4R)-1,3-thiazolidine-4-carboxylic acid

InChIKey

DZLNHFMRPBPULJ-VKHMYHEASA-N

INCHI

1S/C4H7NO2S/c6-4(7)3-1-8-2-5-3/h3,5H,1-2H2,(H,6,7)/t3-/m0/s1

Isomeric SMILES

C1[C@H](NCS1)C(=O)O

WGK Germany

3

RTECS

XJ5425500

PubChem CID

93176

Molecular Weight

133.17

Beilstein

81065

Reaxy-Rn

81065

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Class Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives
            • Level7 Alpha amino acids
              • Level8 L-alpha-amino acids

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Class: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives - Alpha amino acids and derivatives - Alpha amino acids
• Direct Parent: L-alpha-amino acids
• Alternative Parents: Thiazolidines Amino acids Thiohemiaminal derivatives Monocarboxylic acids and derivatives Dialkylthioethers Dialkylamines Carboxylic acids Azacyclic compounds Organopnictogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: L-alpha-amino acid - Thiazolidine - Amino acid - Carboxylic acid - Secondary aliphatic amine - Monocarboxylic acid or derivatives - Secondary amine - Thioether - Hemithioaminal - Dialkylthioether - Organoheterocyclic compound - Azacycle - Organic nitrogen compound - Amine - Carbonyl group - Organonitrogen compound - Organooxygen compound - Organic oxygen compound - Hydrocarbon derivative - Organopnictogen compound - Organic oxide - Aliphatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as l-alpha-amino acids. These are alpha amino acids which have the L-configuration of the alpha-carbon atom.
• External Descriptors: thiazolidinemonocarboxylic acid - thioproline

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

SLC36A1 Tchem Proton-coupled amino acid transporter 1 (102 Activities)

Discover Target: SLC36A1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

ffp 4'-phosphopantetheinyl transferase ffp (24982 Activities)

Discover Target: ffp

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Chemical and Physical Properties

• Sensitivity: Air sensitive
• x_specific_rotation: -200° (C=1,1mol/L NaOH sol.)
• x_melt_point_char: 192-200°C
• Molecular Weight: 133.170 g/mol
• XLogP3: -2.300
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 133.02 Da
• Monoisotopic Mass: 133.02 Da
• Topological Polar Surface Area: 74.600 Ų
• Heavy Atom Count: 8
• Formal Charge: 0
• Complexity: 106.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Frequently Asked Questions

What is the purity of this product, and how is it determined?

This product is supplied at ≥98% purity, determined by HPLC. Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at room temperature under argon. It is supplied under an argon blanket; reseal under inert gas after each use.

How is this product shipped?

This product ships under standard ambient conditions. No temperature-controlled packaging is required.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 34592-47-7, the molecular formula is C4H7NO2S, and the molecular weight is 133.17 g/mol. InChIKey DZLNHFMRPBPULJ-VKHMYHEASA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.