β-lactamase, CAS No.9073-60-3

CAS: 9073-60-3 Cat. No.: L140816 EC Number: 232-970-8 PubChem CID: 133358
AVAILABLE TO ORDER
GRADE & PURITY EnzymoPure™ ? EnzymoPure™ — Aladdin's line of high-quality enzymatic solutions. Use when enzyme purity and defined activity drive assay or process performance. lyophilized powder
Accession #
P00811
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
10MU
L140816-10MU
3

$26.90

$35.90
Save $9.00 (25.07%)
6×10MU
L140816-6×10MU
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.

$142.90

$193.90
Save $51.00 (26.30%)
Enter a quantity for the sizes you want to add.
🧪

Why this grade

EnzymoPure™, lyophilized powder EnzymoPure™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C,Argon charged Ships Wet ice Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 6 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Penicillinase from Bacillus cereus has been shown to contain three distinct species when purified and examined for homogeneity by sedimentation analysis, amino-terminal analysis, and vertical acrylamide gel electrophoresis.
Penicillinase can be used to reduce levels of penicillin in patients with severe penicillin reactions. Used in the production of penicillin. Penicillinase from Bacillus cereus has been used in a comparison study with penicillinase from Bacillus subtillis where the Michaelis constant, shape of the Ph/activity curve and immunological properties were shown to be significantly different. Used in the production of penicillin.

Specifications

Product Name
β-lactamase, CAS No.9073-60-3
Synonyms
CENTA | 80072-86-2 | 9073-60-3 | CENTA(TM) BETA-LACTAMASE SUBSTRATE | (6R, 7R)-3-[(3-carboxy-4-nitrophenyl)sulfanylmethyl]-8-oxo-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid | CHEMBL1650032 | SCHEMBL10876201 | DTXSID40230061 | AKO
Grade
EnzymoPure™
Specifications & Purity
EnzymoPure™, lyophilized powder
Biochemical and Physiological Mechanisms
β--lactamase inactivates β-lactam antibiotics by breaking open the β-lactam ring1. Typical analysis for other substrates: ceftriaxon 2-4 un/mg; cefazolin 2-4 un/mg; ceftazidime 1.5-3 un/mg; cefoxitin 0.35-0.7 un/mg; cefepime 1.2-2.4 un/mg; cefuroxime 1.5-
Accession #
Note
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
CAS
9073-60-3
Enzyme Commission Number
3.5.2.6
Molecule Type
Small molecule
Storage and Shipping
Concentration
lyophilized powder
Storage
Store at 2-8°C,Argon charged
Shipped In
Wet ice
Unit definition
One unit will hydrolyze 1.0 μmol of substrate per minute (βI: benzylpenicillin; βII: cephalosporin C) in 50 mM phosphate buffer pH 7.0 containing 10 μM zinc chloride at 25°C.

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Associated Targets(non-human)
blaZ Beta-lactamase (285 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

5 results found

Lot NumberCertificate TypeDateItem
H2205298Certificate of AnalysisMay 18, 2026 L140816
G2327220Certificate of AnalysisJun 15, 2023 L140816
F2301784Certificate of AnalysisMay 15, 2023 L140816
J2122087Certificate of AnalysisSep 23, 2021 L140816
J2122338Certificate of AnalysisSep 23, 2021 L140816
Documents & Articles
Citations of This Product
References
1. Maohu Chen, Bo Qiu, Zhanlin Zhang, Shuang Xie, Yuan Liu, Tian Xia, Xiaohong Li.  (2021)  Light-triggerable and pH/lipase-responsive release of antibiotics and β-lactamase inhibitors from host-guest self-assembled micelles to combat biofilms and resistant bacteria.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2021.130330]
2. Wenyao Chen, Shan Shan, Juan Peng, Daofeng Liu, Jun Xia, Bing Shao, Weihua Lai.  (2020)  Sensitive and hook effect–free lateral flow assay integrated with cascade signal transduction system.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2020.128465]
3. Shan Shan, Daofeng Liu, Qi Guo, Songsong Wu, Rui Chen, Kai Luo, Liming Hu, Yonghua Xiong, Weihua Lai.  (2016)  Sensitive detection of Escherichia coli O157:H7 based on cascade signal amplification in ELISA.  JOURNAL OF DAIRY SCIENCE,      [PMID:27394946] [10.3168/jds.2016-11320]
4. Chen Chen, Jun Lv, Wanyi Chen, Yang Xiang, Juan Zhang.  (2016)  Colorimetric β-lactamase inhibitor assay with double catalyzed signal amplification.  NEW JOURNAL OF CHEMISTRY,  40  (3): (1982-1987).  [PMID:] [10.1039/C5NJ02356D]
5. Lihong Li, Zhao Li, Wen Shi, Xiaohua Li, Huimin Ma.  (2014)  Sensitive and Selective Near-Infrared Fluorescent Off–On Probe and Its Application to Imaging Different Levels of β-Lactamase in Staphylococcus aureus.  ANALYTICAL CHEMISTRY,      [PMID:24844761] [10.1021/ac501288e]
6. Junfeng Liu, Liying Zhang, Haodi Ma, Haoyang Sun, Shu-ai Ge, Jieyi Liu, Shengdi Fan, Chunshan Quan.  (2024)  Quaternary ammonium chitosan-functionalized mesoporous silica nanoparticles: A promising targeted drug delivery system for the treatment of intracellular MRSA infection.  CARBOHYDRATE POLYMERS,      [PMID:39843087] [10.1016/j.carbpol.2024.123184]
Solution Calculators
Reviews

Customer Reviews

Need help choosing the grade?

Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View EnzymoPure™ grade guide →

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.