Lafutidine - 10mM in DMSO , Histamine H2 receptor antagonist, CAS No.118288-08-7, Histamine H2 receptor antagonist

CAS: 118288-08-7 Cat. No.: L409230 Formula: C22H29N3O4S Molecular Weight: 431.55 EC Number: 601-513-8 PubChem CID: 5282136
AVAILABLE TO ORDER
GRADE & PURITY 10mM in DMSO
Synonyms
FRG-8813 | (+)​-2-​[(2-​furanylmethyl)​sulfinyl]​-​N-​[(2Z)​-​4-​[[4-​(1-​piperidinylmethyl)​-​2-​pyridinyl]​oxy]​-​2-​buten-​1-​yl]​-acetamide
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
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Size
Germany (EU)
USA*
Price
Qty
1ml
L409230-1ml
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2 In stock

€41.56

€60.65
Save €19.09 (31.47%)
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Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 1 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Information

Lafutidine (FRG-8813), a newly developed histamine H(2)-receptor antagonist, inhibits gastric acid secretion.
In vitro


In vivo


Cell Data

cell lines:BT474 cell line and the primary breast cancer cells

Concentrations:

Incubation Time:

Powder Purity:≥99%

Specifications

Synonyms
FRG-8813 | (+)​-2-​[(2-​furanylmethyl)​sulfinyl]​-​N-​[(2Z)​-​4-​[[4-​(1-​piperidinylmethyl)​-​2-​pyridinyl]​oxy]​-​2-​buten-​1-​yl]​-acetamide
Specifications & Purity
10mM in DMSO
Biochemical and Physiological Mechanisms
Lafutidine (FRG-8813), a newly developed histamine H(2)-receptor antagonist, inhibits gastric acid secretion.
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
ANTAGONIST
Mechanism of action
Histamine H2 receptor antagonist
Product Properties
alogp1.4
Names and Identifiers
Isomeric SMILES C1CCN(CC1)CC2=CC(=NC=C2)OC/C=C\CNC(=O)CS(=O)CC3=CC=CO3
RTECS AC2957000
PubChem CID 5282136
Molecular Weight 431.55

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
SolubilitySolubility (25°C) In vitro DMSO: 55 mg/mL (198.35 mM); Water: Insoluble; Ethanol: Insoluble;
x_melt_point_char99 °C
Citations of This Product
References
1. Guodong Shan, Xiuqin Fan, Qingcheng Wang, Li Zhang, Lijun Ge, Weibo Lu, Jing Xue, Kang Chen, Zejun Wang, Qing Shen.  (2025)  Development of a Captiva EMR-lipid clean-up and LC-MS/MS methodology for detecting H2 receptor antagonists in functional foods and food-medicine homology materials.  Applied Food Research,      [PMID:] [10.1016/j.afres.2025.100772]
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