Immune checkpoint modulators
Browse by type, application, or key specifications such as purity, grade, packaging, and handling requirements.
19 products
Popular Products
- Avelumab (anti-PD-L1), OTHER of Programmed cell death 1 ligand 1 otherCAS: 1537032-82-8 PubChem CID: 168266339Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA● In Stock — US warehouse, ships to EU* Item #: A412006View ProductPricing & Pack Sizes
Technical Identifiers
- Associated targets
- CD274
- Short Overview
- Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
- Reactive species
- Cynomolgus monkey, Dog, Human, Mouse, Rabbit, Rat
- Isotype
- Human IgG1
- Host species
- Human
- Conjugation
- Unconjugated
- IUPAC Name
- show more
- SMILES
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- InChIKey
- YRKYEQYAGDIKGE-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- Recombinant Avelumab Antibody | Avelumab | Anti-Human PD-L1, Human Antibody | Anti-PD-L1 | MSB0010718C | Bavencio | B...
- Cemiplimab (anti-PD-1), Antibody of programmed cell death 1 (CD279)CAS: 1801342-60-8Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA● In Stock — US warehouse, ships to EU* Item #: C412010View ProductPricing & Pack Sizes
Technical Identifiers
- Associated targets
- PDCD1
- Short Overview
- Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
- Reactive species
- Human
- Isotype
- Human IgG4
- Host species
- Human
- Conjugation
- Unconjugated
- Synonyms
- hPD-1 | Protein PD-1
- Durvalumab (anti-PD-L1), INHIBITOR of Programmed cell death 1 ligand 1 inhibitorCAS: 1428935-60-7Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA● In Stock — US warehouse, ships to EU* Item #: D412005View ProductPricing & Pack Sizes
Technical Identifiers
- Associated targets
- CD274
- Short Overview
- Purity>95% (SDS-PAGE&SEC); Endotoxin Level<0.01EU/μg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
- Reactive species
- Cynomolgus monkey, Human, Mouse
- Isotype
- Human IgG1
- Host species
- Human
- Conjugation
- Unconjugated
- Synonyms
- Durvalumab (anti-PD-L1) | MEDI4736 | Durvalumab | MEDI 4736 | Anti-B7-H1 / PD-L1 / CD274 Reference Antibody (durvalum...
- Ipilimumab (anti-CTLA-4), Antibody of cytotoxic T-lymphocyte-associated protein 4 (CD152)Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA● In Stock — US warehouse, ships to EU* Item #: I411993View ProductPricing & Pack Sizes
Technical Identifiers
- Associated targets
- CTLA4
- Short Overview
- Purity>95% (SDS-PAGE&SEC); Endotoxin Level<0.01EU/μg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
- Reactive species
- Cynomolgus monkey, Human, Mouse
- Isotype
- Human IgG1
- Host species
- Human
- Conjugation
- Unconjugated
- IUPAC Name
- show more
- SMILES
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- InChIKey
- QZWDCJBBGBXHMW-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- MDX-010 | BMS-734016 | Yervoy | Ipilimumab | Ipilimumab (anti-CTLA-4) | Recombinant Ipilimumab Antibody | Ipilimumab ...
- Pembrolizumab (anti-PD-1), Antibody of programmed cell death 1 (CD279)Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA● In Stock — US warehouse, ships to EU* Item #: P411997View ProductPricing & Pack Sizes
Technical Identifiers
- Associated targets
- PDCD1
- Short Overview
- Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
- Reactive species
- Cynomolgus monkey, Human
- Isotype
- Human IgG4SP
- Host species
- Human
- Conjugation
- Unconjugated
- IUPAC Name
- show more
- SMILES
- CC.CCCCCCCCCCCCC(C)CN(CCCCC=C)CC(CCCCCCCCCCCC)O.CCCCCC=CC=CCCCCCC(C)CN(CCCS)CC(C)CCCCCCC=CC=CCCCC.CCCCN1CCN(CC1)CCC
- InChIKey
- AMOIBCKFWIUEKF-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- 1374853-91-4 | 1-butyl-4-propylpiperazine;ethane;1-[hex-5-enyl(2-methyltetradecyl)amino]tetradecan-2-ol;3-[[(8E,10E)-...
- belatacept, Fusion protein of CD80;Fusion protein of CD86Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.◐ .US Made to order · 2–4 wks Item #: rp173527View ProductPricing & Pack Sizes
Technical Identifiers
- Synonyms
- BMS-224818 | LEA29Y | Nulojix
- programmed cell death 1 ligand 1, programmed cell death 1 (CD279)Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.◐ .US Made to order · 2–4 wks Item #: rp174805View ProductPricing & Pack Sizes
Technical Identifiers
- Synonyms
- B7 homolog 1 | B7-H1 | PD-L1 | PDL1 | programmed death ligand 1
- CCT241533 hydrochloride10mM in DMSO◐ .Made to order · 8–12 wks Item #: C654857View ProductPricing & Pack Sizes
Technical Identifiers
- ANI-710mM in DMSO◐ .Made to order · 8–12 wks Item #: A655580View ProductPricing & Pack Sizes
Technical Identifiers
- CCT244747CAS: 1404095-34-6 Formula: C20H24N8O2 Molecular Weight: 408.46Liquid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO◐ .Made to order · 8–12 wks Item #: C655639View ProductPricing & Pack Sizes
Technical Identifiers
- CCT241533 hydrochloride◐ .Made to order · 8–12 wks Item #: C647075View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-fluoro-2-[4-[[(3S,4R)-4-(2-hydroxypropan-2-yl)pyrrolidin-3-yl]amino]-6,7-dimethoxyquinazolin-2-yl]phenol;hydrochloride
- SMILES
- CC(C)(C1CNCC1NC2=NC(=NC3=CC(=C(C=C32)OC)OC)C4=C(C=CC(=C4)F)O)O.Cl
- InChIKey
- LAKJUTZIXHTMPC-SSPJITILSA-N
- InChI
- show more
- Synonyms
- A908287 | 1431697-96-9 | CCT241533 (hydrochloride) | HY-14715B | F84890 | AKOS030526529 | 4-Fluoro-2-(4-(((3S,4R)-4-(...
- ANI-7◐ .Made to order · 8–12 wks Item #: A648810View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (Z)-2-(3,4-dichlorophenyl)-3-(1H-pyrrol-2-yl)prop-2-enenitrile
- SMILES
- C1=CNC(=C1)C=C(C#N)C2=CC(=C(C=C2)Cl)Cl
- InChIKey
- IJJHHDLGGYDXGD-UXBLZVDNSA-N
- InChI
- 1S/C13H8Cl2N2/c14-12-4-3-9(7-13(12)15)10(8-16)6-11-2-1-5-17-11/h1-7,17H/b10-6+
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Technical Details Quality & specification info on every product page
Pack Size Options Multiple packaging sizes with pricing access from listing
R&D Use Only Products supplied for research and development use
Frequently Asked Questions
What should I consider when selecting an Immune checkpoint modulators product?
Define the transformation first, then narrow the Immune checkpoint modulators listing by reactivity, compatibility with your solvent and temperature window, and scale. Where several grades exist, the higher-purity option is usually worth it for downstream steps that are hard to purify.
What does Immune checkpoint modulators cover?
Immune checkpoint modulators is a top-level listing in our catalogue. Use the filters and search on the listing page to narrow by the attributes that matter for your work, or browse the neighbouring categories from the main navigation.
Which quality data should I check before ordering Immune checkpoint modulators?
Review the lot-specific Certificate of Analysis for the Immune checkpoint modulators product you have chosen: assay or HPLC purity, identity confirmation by NMR and MS, residual solvents where relevant, and appearance. For reactive or hygroscopic material the storage and handling notes matter as much as the purity figure. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search Immune checkpoint modulators by structure or CAS number?
Yes. Within Immune checkpoint modulators you can search by CAS number, molecular formula, or SMILES to reach exact structures and close analogs, and filter by functional group, purity grade, and pack size. For pricing, bulk quantities, or account eligibility, contact [email protected].