Eukaryotic Initiation Factor (eIF)

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  1. Rocaglamide(Roc-A)
    CAS: 84573-16-0 PubChem CID: 331783 Formula: C29H31NO7 Molecular Weight: 505.57
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Made to order · 8–12 wks Item #: R276055
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    IUPAC Name
    (1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxamide
    SMILES
    CN(C)C(=O)C1C(C2(C(C1O)(C3=C(O2)C=C(C=C3OC)OC)O)C4=CC=C(C=C4)OC)C5=CC=CC=C5
    InChIKey
    DAPAQENNNINUPW-IDAMAFBJSA-N
    InChI
    1S/C29H31NO7/c1-30(2)27(32)23-24(17-9-7-6-8-10-17)29(18-11-13-19(34-3)14-12-18)28(33,26(23)31)25-21(36-5)15-20(35-4)16-22(25)37-29/h6-16,23-24,26,31,3show more
    Synonyms
    FRG4N852F7 | B603847K064 | NSC326408 | Rocaglamide | 1H-Cyclopenta(b)benzofuran-2-carboxamide, 2,3,3a,8b-tetrahydro-1...
  2. ATP-gamma-S
    CAS: 93839-89-5 EC Number: 298-862-8 Formula: C10H12Li4N5O12P3S Molecular Weight: 546.98
    ● In Stock — US warehouse, ships to EU* Item #: A274887
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    IUPAC Name
    tetralithium;[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] dioxidophosphinothioyl phosphate
    SMILES
    [Li+].[Li+].[Li+].[Li+].C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)([O-])OP(=O)([O-])OP(=S)([O-])[O-])O)O)N
    InChIKey
    DWQFDOIBOYDYKH-KWIZKVQNSA-J
    InChI
    1S/C10H16N5O12P3S.4Li/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(25-10)1-24-28(18,19)26-29(20,21)27-30(22,23)31;;;;/h2-4,6-7,10,16-17H,1H2,(H,18,19)show more
    Synonyms
    Adenosine 5'-(γ-thio)-triphosphate (lithium salt) | P'-anhydride with phosphorothioic acid adenosine 5'-(trihydrogen ...
  3. 6-Methyl-1H-indole-2-carboxylic acid
    CAS: 18474-59-4 Formula: C10H9NO2 Molecular Weight: 175.18
    ● In Stock — US warehouse, ships to EU* Item #: M182288
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    IUPAC Name
    6-methyl-1H-indole-2-carboxylic acid
    SMILES
    CC1=CC2=C(C=C1)C=C(N2)C(=O)O
    InChIKey
    ZKGSVVHFMZASJS-UHFFFAOYSA-N
    InChI
    1S/C10H9NO2/c1-6-2-3-7-5-9(10(12)13)11-8(7)4-6/h2-5,11H,1H3,(H,12,13)
    Synonyms
    BDBM50305666 | 6-Methyl-1H-indole-2-carboxylic acid, AldrichCPR | MFCD02664477 | EN300-15104 | NCGC00337851-01 | ZKGS...
  4. 2-((5-(((9H-Fluoren-9-ylmethoxy)carbonyl)amino)-10,11-dihydro-5H-dibenzo(a,d)cyclohepten-2-yl)oxy)acetic acid
    CAS: 212783-75-0 Formula: C32H27NO5 Molecular Weight: 505.56
    Solid ≥98%
    ◐ .Made to order · 8–12 wks Item #: S117934
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    IUPAC Name
    2-[[2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-tricyclo[9.4.0.03,8]pentadeca-1(15),3(8),4,6,11,13-hexaenyl]oxy]acetic acid
    SMILES
    C1CC2=C(C=CC(=C2)OCC(=O)O)C(C3=CC=CC=C31)NC(=O)OCC4C5=CC=CC=C5C6=CC=CC=C46
    InChIKey
    XHOBPBDZGGKEOX-UHFFFAOYSA-N
    InChI
    1S/C32H27NO5/c34-30(35)19-37-22-15-16-24-21(17-22)14-13-20-7-1-2-8-23(20)31(24)33-32(36)38-18-29-27-11-5-3-9-25(27)26-10-4-6-12-28(26)29/h1-12,15-17,2show more
    Synonyms
    AC-32003 | SCHEMBL22572694 | MFCD07783960 | J-013969 | BCP16052 | FT-0643964 | 2-[[5-[[(9H-Fluoren-9-ylmethoxy)carbon...
  5. 4E1RCat
    CAS: 328998-25-0 Formula: C28H18N2O6 Molecular Weight: 478.45
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: E423360
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    IUPAC Name
    4-[(3Z)-3-[[5-(4-nitrophenyl)furan-2-yl]methylidene]-2-oxo-5-phenylpyrrol-1-yl]benzoic acid
    SMILES
    C1=CC=C(C=C1)C2=CC(=CC3=CC=C(O3)C4=CC=C(C=C4)[N+](=O)[O-])C(=O)N2C5=CC=C(C=C5)C(=O)O
    InChIKey
    BBQRBOIMSKMFFO-PGMHBOJBSA-N
    InChI
    1S/C28H18N2O6/c31-27-21(16-24-14-15-26(36-24)19-6-12-23(13-7-19)30(34)35)17-25(18-4-2-1-3-5-18)29(27)22-10-8-20(9-11-22)28(32)33/h1-17H,(H,32,33)/b21-show more
    Synonyms
    4-[(3E)-3-[[5-(4-nitrophenyl)furan-2-yl]methylidene]-2-oxo-5-phenylpyrrol-1-yl]benzoic acid
  6. 4E1RCat
    CAS: 328998-25-0 Formula: C28H18N2O6 Molecular Weight: 478.45
    ● In Stock — US warehouse, ships to EU* Item #: E345401
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    Technical Identifiers
    IUPAC Name
    4-[(3Z)-3-[[5-(4-nitrophenyl)furan-2-yl]methylidene]-2-oxo-5-phenylpyrrol-1-yl]benzoic acid
    SMILES
    C1=CC=C(C=C1)C2=CC(=CC3=CC=C(O3)C4=CC=C(C=C4)[N+](=O)[O-])C(=O)N2C5=CC=C(C=C5)C(=O)O
    InChIKey
    BBQRBOIMSKMFFO-PGMHBOJBSA-N
    InChI
    1S/C28H18N2O6/c31-27-21(16-24-14-15-26(36-24)19-6-12-23(13-7-19)30(34)35)17-25(18-4-2-1-3-5-18)29(27)22-10-8-20(9-11-22)28(32)33/h1-17H,(H,32,33)/b21-show more
    Synonyms
    4-[(3E)-3-[[5-(4-nitrophenyl)furan-2-yl]methylidene]-2-oxo-5-phenylpyrrol-1-yl]benzoic acid
  7. 4E2RCat
    CAS: 432499-63-3 PubChem CID: 2287236 Formula: C22H14ClNO4S2 Molecular Weight: 455.93
    ≥98% mixture of isomers
    ● In Stock — US warehouse, ships to EU* Item #: E412440
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    IUPAC Name
    5-[5-[(Z)-(3-benzyl-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]furan-2-yl]-2-chlorobenzoic acid
    SMILES
    C1=CC=C(C=C1)CN2C(=O)C(=CC3=CC=C(O3)C4=CC(=C(C=C4)Cl)C(=O)O)SC2=S
    InChIKey
    WOBPZFKXPCYOLU-ODLFYWEKSA-N
    InChI
    1S/C22H14ClNO4S2/c23-17-8-6-14(10-16(17)21(26)27)18-9-7-15(28-18)11-19-20(25)24(22(29)30-19)12-13-4-2-1-3-5-13/h1-11H,12H2,(H,26,27)/b19-11-
    Synonyms
    PD103111 | BS-51906 | 5-[5-[(Z)-(3-benzyl-4-oxo-2-thioxo-thiazolidin-5-ylidene)methyl]-2-furyl]-2-chloro-benzoic acid...
  8. Briciclib, G1/S-specific cyclin D1 inhibitor
    CAS: 865783-99-9 PubChem CID: 11248490 Formula: C19H23O10PS Molecular Weight: 474.42
    ● In Stock — US warehouse, ships to EU* Item #: B413506
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    IUPAC Name
    [2-methoxy-5-[[(E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonylmethyl]phenyl] dihydrogen phosphate
    SMILES
    COC1=C(C=C(C=C1)CS(=O)(=O)C=CC2=C(C=C(C=C2OC)OC)OC)OP(=O)(O)O
    InChIKey
    LXENKEWVEVKKGV-BQYQJAHWSA-N
    InChI
    1S/C19H23O10PS/c1-25-14-10-17(27-3)15(18(11-14)28-4)7-8-31(23,24)12-13-5-6-16(26-2)19(9-13)29-30(20,21)22/h5-11H,12H2,1-4H3,(H2,20,21,22)/b8-7+
    Synonyms
    AC-36098 | s6533 | 2-Methoxy-5-(((2-(2,4,6-trimethoxyphenyl)ethenyl)sulfonyl)methyl)phenyl dihydrogen phosphate | Bri...
  9. Briciclib, G1/S-specific cyclin D1 inhibitor
    CAS: 865783-99-9 PubChem CID: 11248490 Formula: C19H23O10PS Molecular Weight: 474.42
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: B426444
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    Technical Identifiers
    IUPAC Name
    [2-methoxy-5-[[(E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonylmethyl]phenyl] dihydrogen phosphate
    SMILES
    COC1=C(C=C(C=C1)CS(=O)(=O)C=CC2=C(C=C(C=C2OC)OC)OC)OP(=O)(O)O
    InChIKey
    LXENKEWVEVKKGV-BQYQJAHWSA-N
    InChI
    1S/C19H23O10PS/c1-25-14-10-17(27-3)15(18(11-14)28-4)7-8-31(23,24)12-13-5-6-16(26-2)19(9-13)29-30(20,21)22/h5-11H,12H2,1-4H3,(H2,20,21,22)/b8-7+
    Synonyms
    AC-36098 | s6533 | 2-Methoxy-5-(((2-(2,4,6-trimethoxyphenyl)ethenyl)sulfonyl)methyl)phenyl dihydrogen phosphate | Bri...
  10. Episilvestrol
    CAS: 697235-39-5 Formula: C34H38O13 Molecular Weight: 654.66
    ◐ .Made to order · 8–12 wks Item #: E126128
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    IUPAC Name
    methyl (1R,2R,3S,3aR,8bS)-6-[[(2S,3R,6R)-6-[(1S)-1,2-dihydroxyethyl]-3-methoxy-1,4-dioxan-2-yl]oxy]-1,8b-dihydroxy-8-methoxy-3a-(4-methoxyphenyl)-3-phshow more
    SMILES
    COC1C(OC(CO1)C(CO)O)OC2=CC3=C(C(=C2)OC)C4(C(C(C(C4(O3)C5=CC=C(C=C5)OC)C6=CC=CC=C6)C(=O)OC)O)O
    InChIKey
    GVKXFVCXBFGBCD-JRPGFILLSA-N
    InChI
    1S/C34H38O13/c1-40-20-12-10-19(11-13-20)34-27(18-8-6-5-7-9-18)26(30(38)42-3)29(37)33(34,39)28-23(41-2)14-21(15-24(28)47-34)45-32-31(43-4)44-17-25(46-3show more
    Synonyms
    DTXSID80466766 | CHEBI:66485 | Episilvestrol | epi-silvestrol | EX-A4881 | MS-30981 | HY-15359 | methyl (1R,2R,3S,3aR...
  11. GCN2iB
    CAS: 2183470-12-2 Formula: C18H12ClF2N5O3S Molecular Weight: 451.83
    ● In Stock — US warehouse, ships to EU* Item #: G414275
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    IUPAC Name
    N-[3-[2-(2-aminopyrimidin-5-yl)ethynyl]-2,4-difluorophenyl]-5-chloro-2-methoxypyridine-3-sulfonamide
    SMILES
    COC1=C(C=C(C=N1)Cl)S(=O)(=O)NC2=C(C(=C(C=C2)F)C#CC3=CN=C(N=C3)N)F
    InChIKey
    JGHVXJKGYJYWOP-UHFFFAOYSA-N
    InChI
    1S/C18H12ClF2N5O3S/c1-29-17-15(6-11(19)9-23-17)30(27,28)26-14-5-4-13(20)12(16(14)21)3-2-10-7-24-18(22)25-8-10/h4-9,26H,1H3,(H2,22,24,25)
    Synonyms
    N-[3-[2-(2-Amino-5-pyrimidinyl)ethynyl]-2,4-difluorophenyl]-5-chloro-2-methoxy- 3-pyridinesulfonamide
  12. GCN2iB
    CAS: 2183470-12-2 Formula: C18H12ClF2N5O3S Molecular Weight: 451.83
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: G422624
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    Technical Identifiers
    IUPAC Name
    N-[3-[2-(2-aminopyrimidin-5-yl)ethynyl]-2,4-difluorophenyl]-5-chloro-2-methoxypyridine-3-sulfonamide
    SMILES
    COC1=C(C=C(C=N1)Cl)S(=O)(=O)NC2=C(C(=C(C=C2)F)C#CC3=CN=C(N=C3)N)F
    InChIKey
    JGHVXJKGYJYWOP-UHFFFAOYSA-N
    InChI
    1S/C18H12ClF2N5O3S/c1-29-17-15(6-11(19)9-23-17)30(27,28)26-14-5-4-13(20)12(16(14)21)3-2-10-7-24-18(22)25-8-10/h4-9,26H,1H3,(H2,22,24,25)
    Synonyms
    3-​Pyridinesulfonamide,N-​[3-​[2-​(2-​amino-​5-​pyrimidinyl)​ethynyl]​-​2,​4-​difluorophenyl]​-​5-​chloro-​2-​methoxy-
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Frequently Asked Questions

What can I find under Eukaryotic Initiation Factor (eIF)?
This listing collects compounds associated with Eukaryotic Initiation Factor (eIF) within our Cell Cycle/DNA Damage area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.
What should I consider when picking a compound for Eukaryotic Initiation Factor (eIF)?
Consider the reported potency of each Eukaryotic Initiation Factor (eIF) compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.
What quality information is provided for Eukaryotic Initiation Factor (eIF) compounds?
Each Eukaryotic Initiation Factor (eIF) product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search Eukaryotic Initiation Factor (eIF) compounds by activity or structure?
Yes. Filter the Eukaryotic Initiation Factor (eIF) listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].

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