IRE1
Browse by type, application, or key specifications such as purity, grade, packaging, and handling requirements.
57 products
Popular Products
- 6-Bromo-2-hydroxy-3-methoxybenzaldehyde● In Stock — US warehouse, ships to EU* Item #: B153189View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 6-bromo-2-hydroxy-3-methoxybenzaldehyde
- SMILES
- COC1=C(C(=C(C=C1)Br)C=O)O
- InChIKey
- JUPJZUTYDWXZAQ-UHFFFAOYSA-N
- InChI
- 1S/C8H7BrO3/c1-12-7-3-2-6(9)5(4-10)8(7)11/h2-4,11H,1H3
- Synonyms
- EN300-6498200 | J-012961 | SCHEMBL424251 | 6-Bromo-2-hydroxy-3-methoxybenzaldehyde, 98% | FT-0637938 | J-510172 | DS-...
- APY 29CAS: 1216665-49-4 Formula: C17H16N8 Molecular Weight: 332.36● In Stock — US warehouse, ships to EU* Item #: A288548View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-N-(3H-benzimidazol-5-yl)-4-N-(5-cyclopropyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine
- SMILES
- C1CC1C2=CC(=NN2)NC3=NC(=NC=C3)NC4=CC5=C(C=C4)N=CN5
- InChIKey
- WJNBSTLIALIIEW-UHFFFAOYSA-N
- InChI
- 1S/C17H16N8/c1-2-10(1)13-8-16(25-24-13)22-15-5-6-18-17(23-15)21-11-3-4-12-14(7-11)20-9-19-12/h3-10H,1-2H2,(H,19,20)(H3,18,21,22,23,24,25)
- Synonyms
- (E)-N-(6-((5-cyclopropyl-1H-pyrazol-3-yl)imino)-1,6-dihydropyrimidin-2-yl)-1H-benzo[d]imidazol-6-amine | N2-1H-Benzim...
- Diphenylcyclopropenone(DPC)Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: A115107View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2,3-diphenylcycloprop-2-en-1-one
- SMILES
- C1=CC=C(C=C1)C2=C(C2=O)C3=CC=CC=C3
- InChIKey
- HCIBTBXNLVOFER-UHFFFAOYSA-N
- InChI
- 1S/C15H10O/c16-15-13(11-7-3-1-4-8-11)14(15)12-9-5-2-6-10-12/h1-10H
- Synonyms
- DPC | Cyclopropenone, 2,3-diphenyl- | NCGC00166113-01 | SR-01000644630-1 | AMY1261 | DIPHENCYPRONE [MI] | DIPHENYLCYC...
- B I09CAS: 1607803-67-7 Formula: C16H17NO5 Molecular Weight: 303.31◐ .Made to order · 8–12 wks Item #: B287381View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 7-(1,3-dioxan-2-yl)-8-hydroxy-1,2,3,4-tetrahydrochromeno[3,4-c]pyridin-5-one
- SMILES
- C1COC(OC1)C2=C(C=CC3=C2OC(=O)C4=C3CCNC4)O
- InChIKey
- UYYMWNUDIOPESF-UHFFFAOYSA-N
- InChI
- 1S/C16H17NO5/c18-12-3-2-10-9-4-5-17-8-11(9)15(19)22-14(10)13(12)16-20-6-1-7-21-16/h2-3,16-18H,1,4-8H2
- Synonyms
- 7-(1,3-Dioxan-2-yl)-1,2,3,4-tetrahydro-8-hydroxy-5H-[1]benzopyrano[3,4-c]pyridin-5-one
- Sunitinib Malate, Tyrosine-protein kinase receptor RET inhibitor● In Stock — US warehouse, ships to EU* Item #: E129728View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide;(2S)-2-hydroxybutanedioic acid
- SMILES
- CCN(CC)CCNC(=O)C1=C(NC(=C1C)C=C2C3=C(C=CC(=C3)F)NC2=O)C.C(C(C(=O)O)O)C(=O)O
- InChIKey
- LBWFXVZLPYTWQI-IPOVEDGCSA-N
- InChI
- show more
- Synonyms
- 1H-Pyrrole-3-carboxamide, N-(2-(diethylamino)ethyl)-5-((Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl)-2,4...
- Sunitinib, Inhibitor of fibroblast growth factor receptor 1;Inhibitor of fms related receptor tyrosine kinase 3;Inhibitor of fms related receptor tyrosine kinase 4;Inhibitor of kinase insert domain receptor;Inhibitor of KIT proto-oncogene; receptor tyrosine kinase;ICAS: 557795-19-4 EC Number: 111-194-2 PubChem CID: 5329102 Formula: C22H27FN4O2 Molecular Weight: 398.47Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● In Stock — US warehouse, ships to EU* Item #: S126061View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
- SMILES
- CCN(CC)CCNC(=O)C1=C(NC(=C1C)C=C2C3=C(C=CC(=C3)F)NC2=O)C
- InChIKey
- WINHZLLDWRZWRT-ATVHPVEESA-N
- InChI
- show more
- Synonyms
- 1H-Pyrrole-3-carboxamide,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl- | D08552 | C22H27FN4O2 | N-(2-(Diet...
- Toyocamycin● In Stock — US warehouse, ships to EU* Item #: T275971View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrrolo[2,3-d]pyrimidine-5-carbonitrile
- SMILES
- C1=C(C2=C(N=CN=C2N1C3C(C(C(O3)CO)O)O)N)C#N
- InChIKey
- XOKJUSAYZUAMGJ-WOUKDFQISA-N
- InChI
- 1S/C12H13N5O4/c13-1-5-2-17(11-7(5)10(14)15-4-16-11)12-9(20)8(19)6(3-18)21-12/h2,4,6,8-9,12,18-20H,3H2,(H2,14,15,16)/t6-,8-,9-,12-/m1/s1
- Synonyms
- L7995C4D7F | 4-Amino-7-.beta.-D-ribofuranosyl-7H-pyrrolo(2,3-d)pyrimidine-5-carbonitrile | NSC-99843 | Antibiotic E21...
- 4μ8C● In Stock — US warehouse, ships to EU* Item #: C167186View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 7-hydroxy-4-methyl-2-oxochromene-8-carbaldehyde
- SMILES
- CC1=CC(=O)OC2=C1C=CC(=C2C=O)O
- InChIKey
- RTHHSXOVIJWFQP-UHFFFAOYSA-N
- InChI
- 1S/C11H8O4/c1-6-4-10(14)15-11-7(6)2-3-9(13)8(11)5-12/h2-5,13H,1H3
- Synonyms
- IRE1 Inhibitor III | BB 0256929 | HMS3653K06 | 4?8C | F2158-2222 | 8-formyl-7-hydroxy-4-methylcoumarin | IRE1 Inhibit...
- 4μ8C10mM in DMSO● In Stock — US warehouse, ships to EU* Item #: C421493View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 7-hydroxy-4-methyl-2-oxochromene-8-carbaldehyde
- SMILES
- CC1=CC(=O)OC2=C1C=CC(=C2C=O)O
- InChIKey
- RTHHSXOVIJWFQP-UHFFFAOYSA-N
- InChI
- 1S/C11H8O4/c1-6-4-10(14)15-11-7(6)2-3-9(13)8(11)5-12/h2-5,13H,1H3
- Synonyms
- BB 0256929 | HMS3653K06 | 4?8C | F2158-2222 | 8-formyl-7-hydroxy-4-methylcoumarin | IRE1 Inhibitor III | J-007348 | S...
- 6-Bromo-2-hydroxy-3-methoxybenzaldehyde10mM in DMSO● In Stock — US warehouse, ships to EU* Item #: B422438View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 6-bromo-2-hydroxy-3-methoxybenzaldehyde
- SMILES
- COC1=C(C(=C(C=C1)Br)C=O)O
- InChIKey
- JUPJZUTYDWXZAQ-UHFFFAOYSA-N
- InChI
- 1S/C8H7BrO3/c1-12-7-3-2-6(9)5(4-10)8(7)11/h2-4,11H,1H3
- Synonyms
- EN300-6498200 | J-012961 | SCHEMBL424251 | 6-Bromo-2-hydroxy-3-methoxybenzaldehyde, 98% | FT-0637938 | J-510172 | DS-...
- AMG 18 hydrochloride● In Stock — US warehouse, ships to EU* Item #: A288841View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-chloro-N-[6-methyl-5-[3-[2-[[(3S)-piperidin-3-yl]amino]pyrimidin-4-yl]pyridin-2-yl]oxynaphthalen-1-yl]benzenesulfonamide;hydrochloride
- SMILES
- CC1=C(C2=C(C=C1)C(=CC=C2)NS(=O)(=O)C3=CC=CC=C3Cl)OC4=C(C=CC=N4)C5=NC(=NC=C5)NC6CCCNC6.Cl
- InChIKey
- CNWIPRHGMZTPSB-BOXHHOBZSA-N
- InChI
- show more
- Synonyms
- 2-Chloro-N-[6-methyl-5-[[3-[2-[(3S)-3-piperidinylamino]-4-pyrimidinyl]-2-pyridinyl]oxy]-1-naphthalenyl]benzenesulfona...
- APY 29CAS: 1216665-49-4 Formula: C17H16N8 Molecular Weight: 332.3610mM in DMSO● In Stock — US warehouse, ships to EU* Item #: A420934View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-N-(3H-benzimidazol-5-yl)-4-N-(5-cyclopropyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine
- SMILES
- C1CC1C2=CC(=NN2)NC3=NC(=NC=C3)NC4=CC5=C(C=C4)N=CN5
- InChIKey
- WJNBSTLIALIIEW-UHFFFAOYSA-N
- InChI
- 1S/C17H16N8/c1-2-10(1)13-8-16(25-24-13)22-15-5-6-18-17(23-15)21-11-3-4-12-14(7-11)20-9-19-12/h3-10H,1-2H2,(H,19,20)(H3,18,21,22,23,24,25)
- Synonyms
- (E)-N-(6-((5-cyclopropyl-1H-pyrazol-3-yl)imino)-1,6-dihydropyrimidin-2-yl)-1H-benzo[d]imidazol-6-amine;N2-1H-Benzimid...
Fast Shipping Same-day shipping on in-stock items
Technical Details Quality & specification info on every product page
Pack Size Options Multiple packaging sizes with pricing access from listing
R&D Use Only Products supplied for research and development use
Frequently Asked Questions
How is the IRE1 listing put together?
It draws on reported IRE1 annotations within Cell Cycle/DNA Damage and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose an IRE1 modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the IRE1 entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for IRE1 compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For IRE1 work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the IRE1 compound I need is not listed?
Search by CAS number or SMILES first, since analogs of IRE1 compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.