Histone Methyltransferase

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  1. GSK503
    CAS: 1346572-63-1 Formula: C31H38N6O2 Molecular Weight: 526.67
    ● In Stock — US warehouse, ships to EU* Item #: G276508
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    IUPAC Name
    N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-3-methyl-6-[6-(4-methylpiperazin-1-yl)pyridin-3-yl]-1-propan-2-ylindole-4-carboxamide
    SMILES
    CC1=CC(=C(C(=O)N1)CNC(=O)C2=C3C(=CN(C3=CC(=C2)C4=CN=C(C=C4)N5CCN(CC5)C)C(C)C)C)C
    InChIKey
    HRDQQHUKUIKFHT-UHFFFAOYSA-N
    InChI
    1S/C31H38N6O2/c1-19(2)37-18-21(4)29-25(30(38)33-17-26-20(3)13-22(5)34-31(26)39)14-24(15-27(29)37)23-7-8-28(32-16-23)36-11-9-35(6)10-12-36/h7-8,13-16,1show more
    Synonyms
    N-[(1,2-Dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-3-methyl-1-(1-methylethyl)-6-[6-(4-methyl-1-piperazinyl)-3-pyr...
  2. Furamidine dihydrochloride
    CAS: 55368-40-6 PubChem CID: 9799856 Formula: C18H16N4O · 2HCl Molecular Weight: 377.27
    ● In Stock — US warehouse, ships to EU* Item #: F286803
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    IUPAC Name
    4-[5-(4-carbamimidoylphenyl)furan-2-yl]benzenecarboximidamide;dihydrochloride
    SMILES
    C1=CC(=CC=C1C2=CC=C(O2)C3=CC=C(C=C3)C(=N)N)C(=N)N.Cl.Cl
    InChIKey
    VXNYQUQHOUERTR-UHFFFAOYSA-N
    InChI
    1S/C18H16N4O.2ClH/c19-17(20)13-5-1-11(2-6-13)15-9-10-16(23-15)12-3-7-14(8-4-12)18(21)22;;/h1-10H,(H3,19,20)(H3,21,22);2*1H
    Synonyms
    DB 75 | DB75 | NSC 305831 | WR199385 | 4-[5-(4-carbamimidoylphenyl)furan-2-yl]benzenecarboximidamide;dihydrochloride ...
  3. ZLD 1039
    CAS: 1826865-46-6 PubChem CID: 132517142 Formula: C36H48N6O3 Molecular Weight: 612.8
    ● In Stock — US warehouse, ships to EU* Item #: Z287041
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    IUPAC Name
    3-[ethyl(oxan-4-yl)amino]-2-methyl-N-[(1-methyl-3-oxo-5,6,7,8-tetrahydro-2H-isoquinolin-4-yl)methyl]-5-[6-(4-methylpiperazin-1-yl)pyridin-3-yl]benzamishow more
    SMILES
    CCN(C1CCOCC1)C2=CC(=CC(=C2C)C(=O)NCC3=C4CCCCC4=C(NC3=O)C)C5=CN=C(C=C5)N6CCN(CC6)C
    InChIKey
    SZAYCVHJDOWSNY-UHFFFAOYSA-N
    InChI
    1S/C36H48N6O3/c1-5-42(28-12-18-45-19-13-28)33-21-27(26-10-11-34(37-22-26)41-16-14-40(4)15-17-41)20-31(24(33)2)35(43)38-23-32-30-9-7-6-8-29(30)25(3)39-show more
    Synonyms
    3-[Ethyl(tetrahydro-2H-pyran-4-yl)amino]-N-[(2,3,5,6,7,8-hexahydro-1-methyl-3-oxo-4-isoquinolinyl)methyl]-2-methyl-5-...
  4. (S)-PFI 2 hydrochloride
    CAS: 1627607-88-8 PubChem CID: 91691132 Formula: C₂₃H₂₅F₄N₃O₃S•HCl Molecular Weight: 535.98
    ◐ .Made to order · 8–12 wks Item #: S287365
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    IUPAC Name
    8-fluoro-N-[(2S)-1-oxo-1-pyrrolidin-1-yl-3-[3-(trifluoromethyl)phenyl]propan-2-yl]-1,2,3,4-tetrahydroisoquinoline-6-sulfonamide;hydrochloride
    SMILES
    C1CCN(C1)C(=O)C(CC2=CC(=CC=C2)C(F)(F)F)NS(=O)(=O)C3=CC4=C(CNCC4)C(=C3)F.Cl
    InChIKey
    ZADKZNVAJGEFLC-BOXHHOBZSA-N
    InChI
    1S/C23H25F4N3O3S.ClH/c24-20-13-18(12-16-6-7-28-14-19(16)20)34(32,33)29-21(22(31)30-8-1-2-9-30)11-15-4-3-5-17(10-15)23(25,26)27;/h3-5,10,12-13,21,28-29show more
    Synonyms
    (S)-PFI-2 | 8-fluoro-N-[(2S)-1-oxo-1-pyrrolidin-1-yl-3-[3-(trifluoromethyl)phenyl]propan-2-yl]-1,2,3,4-tetrahydroisoq...
  5. SGC 0946, Inhibitor of DOT1 like histone lysine methyltransferase
    CAS: 1561178-17-3 EC Number: 808-588-8 PubChem CID: 56962337 Formula: C28H40BrN7O4 Molecular Weight: 618.57
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%(HPLC)
    ● In Stock — US warehouse, ships to EU* Item #: S286970
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    IUPAC Name
    1-[3-[[(2R,3S,4R,5R)-5-(4-amino-5-bromopyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxyoxolan-2-yl]methyl-propan-2-ylamino]propyl]-3-(4-tert-butylphenyl)urshow more
    SMILES
    CC(C)N(CCCNC(=O)NC1=CC=C(C=C1)C(C)(C)C)CC2C(C(C(O2)N3C=C(C4=C(N=CN=C43)N)Br)O)O
    InChIKey
    IQCKJUKAQJINMK-HUBRGWSESA-N
    InChI
    1S/C28H40BrN7O4/c1-16(2)35(12-6-11-31-27(39)34-18-9-7-17(8-10-18)28(3,4)5)14-20-22(37)23(38)26(40-20)36-13-19(29)21-24(30)32-15-33-25(21)36/h7-10,13,1show more
    Synonyms
    1-(3-((((2R,3S,4R,5R)-5-(4-Amino-5-bromo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(i...
  6. OICR 9429, Inhibitor of WD repeat domain 5
    CAS: 1801787-56-3 Formula: C29H32F3N5O3 Molecular Weight: 555.59
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ● In Stock — US warehouse, ships to EU* Item #: O287472
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    IUPAC Name
    N-[2-(4-methylpiperazin-1-yl)-5-[3-(morpholin-4-ylmethyl)phenyl]phenyl]-6-oxo-4-(trifluoromethyl)-1H-pyridine-3-carboxamide
    SMILES
    CN1CCN(CC1)C2=C(C=C(C=C2)C3=CC=CC(=C3)CN4CCOCC4)NC(=O)C5=CNC(=O)C=C5C(F)(F)F
    InChIKey
    DJOVLOYCGXNVPI-UHFFFAOYSA-N
    InChI
    1S/C29H32F3N5O3/c1-35-7-9-37(10-8-35)26-6-5-22(21-4-2-3-20(15-21)19-36-11-13-40-14-12-36)16-25(26)34-28(39)23-18-33-27(38)17-24(23)29(30,31)32/h2-6,15show more
    Synonyms
    N-[2-(4-Methylpiperazin-1-yl)-5-[3-(morpholin-4-ylmethyl)phenyl]phenyl]-6-oxo-4-(trifluoromethyl)-1,6-dihydropyridine...
  7. MS 023 dihydrochloride
    CAS: 1992047-64-9 PubChem CID: 121513886 Formula: C17H25N3O.2HCl Molecular Weight: 360.32
    ● In Stock — US warehouse, ships to EU* Item #: M288905
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    IUPAC Name
    N'-methyl-N'-[[4-(4-propan-2-yloxyphenyl)-1H-pyrrol-3-yl]methyl]ethane-1,2-diamine;dihydrochloride
    SMILES
    CC(C)OC1=CC=C(C=C1)C2=CNC=C2CN(C)CCN.Cl.Cl
    InChIKey
    HCNXCUFNZWGILO-UHFFFAOYSA-N
    InChI
    1S/C17H25N3O.2ClH/c1-13(2)21-16-6-4-14(5-7-16)17-11-19-10-15(17)12-20(3)9-8-18;;/h4-7,10-11,13,19H,8-9,12,18H2,1-3H3;2*1H
    Synonyms
    N1-Methyl-N1-[[4-[4-(1-methylethoxy)phenyl]-1H-pyrrol-3-yl]methyl]-1,2-ethanediamine dihydrochloride
  8. NSC 663284 (DA3003-1)
    CAS: 383907-43-5 EC Number: 636-814-3 Formula: C15H16ClN3O3 Molecular Weight: 321.76
    ● In Stock — US warehouse, ships to EU* Item #: N275722
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    IUPAC Name
    6-chloro-7-(2-morpholin-4-ylethylamino)quinoline-5,8-dione
    SMILES
    C1COCCN1CCNC2=C(C(=O)C3=C(C2=O)N=CC=C3)Cl
    InChIKey
    BMKPVDQDJQWBPD-UHFFFAOYSA-N
    InChI
    1S/C15H16ClN3O3/c16-11-13(18-4-5-19-6-8-22-9-7-19)15(21)12-10(14(11)20)2-1-3-17-12/h1-3,18H,4-9H2
    Synonyms
    NCGC00092289-02 | 6-Chloro-7-[[2-(4-morpholinyl)ethyl]amino]-5,8-quinolinedione | NCI60_021732 | 5,6-chloro-7-[[2-(4-...
  9. Piribedil, Agonist of 5-HT 1A receptor;Antagonist of 5-HT 2B receptor;Antagonist of α 1A-adrenoceptor;Antagonist of α 2A-adrenoceptor;Antagonist of α 2C-adrenoceptor;Agonist of D 2 receptor;Agonist of D 3 receptor;Antagonist of D 4 receptor
    CAS: 3605-01-4 EC Number: 222-764-6 PubChem CID: 4850 Formula: C16H18N4O2 Molecular Weight: 298.35
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ● In Stock — US warehouse, ships to EU* Item #: P160771
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    IUPAC Name
    2-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]pyrimidine
    SMILES
    C1CN(CCN1CC2=CC3=C(C=C2)OCO3)C4=NC=CC=N4
    InChIKey
    OQDPVLVUJFGPGQ-UHFFFAOYSA-N
    InChI
    1S/C16H18N4O2/c1-4-17-16(18-5-1)20-8-6-19(7-9-20)11-13-2-3-14-15(10-13)22-12-21-14/h1-5,10H,6-9,11-12H2
    Synonyms
    Oprea1_061309 | BRD-K47936004-003-03-1 | EU 4200 | PIRIBEDIL [MI] | AB00514645-19 | BRN 0963637 | CAS_3605-01-4 | ES-...
  10. Inhibitor 6e (PRMT1 inhibitor 6e)
    CAS: 1025948-98-4 Formula: C20H7Br6NO5 Molecular Weight: 820.7
    ◐ .Made to order · 8–12 wks Item #: I275552
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    IUPAC Name
    4-amino-3,5-dibromo-2-(2,4,5,7-tetrabromo-3-hydroxy-6-oxoxanthen-9-yl)benzoic acid
    SMILES
    C1=C2C(=C3C=C(C(=O)C(=C3OC2=C(C(=C1Br)O)Br)Br)Br)C4=C(C(=C(C=C4C(=O)O)Br)N)Br
    InChIKey
    PSILLVDSFALROT-UHFFFAOYSA-N
    InChI
    1S/C20H7Br6NO5/c21-7-3-6(20(30)31)11(12(24)15(7)27)10-4-1-8(22)16(28)13(25)18(4)32-19-5(10)2-9(23)17(29)14(19)26/h1-3,28H,27H2,(H,30,31)
    Synonyms
    4-Amino-3,5-dibromo-2-(2,4,5,7-tetrabromo-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoicacid
  11. Pinometostat (EPZ5676), Inhibitor of DOT1 like histone lysine methyltransferase
    CAS: 1380288-87-8 Formula: C30H42N8O3 Molecular Weight: 562.71
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: E125307
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    IUPAC Name
    (2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-[[[3-[2-(6-tert-butyl-1H-benzimidazol-2-yl)ethyl]cyclobutyl]-propan-2-ylamino]methyl]oxolane-3,4-diol
    SMILES
    CC(C)N(CC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)O)C4CC(C4)CCC5=NC6=C(N5)C=C(C=C6)C(C)(C)C
    InChIKey
    LXFOLMYKSYSZQS-XKHGBIBOSA-N
    InChI
    1S/C30H42N8O3/c1-16(2)37(13-22-25(39)26(40)29(41-22)38-15-34-24-27(31)32-14-33-28(24)38)19-10-17(11-19)6-9-23-35-20-8-7-18(30(3,4)5)12-21(20)36-23/h7-show more
    Synonyms
    (2R,3R,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-(((3-(2-(5-(tert-butyl)-1H-benzo[d]imidazol-2-yl)ethyl)cyclobutyl)(isopropy...
  12. UNC0638, Inhibitor of euchromatic histone lysine methyltransferase 1;Inhibitor of euchromatic histone lysine methyltransferase 2
    CAS: 1255580-76-7 PubChem CID: 46224516 Formula: C30H47N5O2 Molecular Weight: 509.73
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: U275196
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    IUPAC Name
    2-cyclohexyl-6-methoxy-N-(1-propan-2-ylpiperidin-4-yl)-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-amine
    SMILES
    CC(C)N1CCC(CC1)NC2=NC(=NC3=CC(=C(C=C32)OC)OCCCN4CCCC4)C5CCCCC5
    InChIKey
    QOECJCJVIMVJGX-UHFFFAOYSA-N
    InChI
    1S/C30H47N5O2/c1-22(2)35-17-12-24(13-18-35)31-30-25-20-27(36-3)28(37-19-9-16-34-14-7-8-15-34)21-26(25)32-29(33-30)23-10-5-4-6-11-23/h20-24H,4-19H2,1-3show more
    Synonyms
    AC-32711 | AS-74910 | CCG-208706 | J-509244 | SB19045 | DTXSID30154787 | NSC764517 | NSC-764517 | 2-Cyclohexyl-6-meth...
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Frequently Asked Questions

What can I find under Histone Methyltransferase?
This listing collects compounds associated with Histone Methyltransferase within our Epigenetics area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.
What should I consider when picking a compound for Histone Methyltransferase?
Consider the reported potency of each Histone Methyltransferase compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.
What quality information is provided for Histone Methyltransferase compounds?
Each Histone Methyltransferase product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search Histone Methyltransferase compounds by activity or structure?
Yes. Filter the Histone Methyltransferase listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].

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