CD28
Browse by type, application, or key specifications such as purity, grade, packaging, and handling requirements.
22 products
Popular Products
- MDK 24720 (CTLA-4 inhibitor)CAS: 635324-72-0 Formula: C21H13F4N5O Molecular Weight: 427.35● In Stock — US warehouse, ships to EU* Item #: M412249View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-(4-fluorophenyl)-10-methyl-7-[3-(trifluoromethyl)phenyl]-3,4,8,10,11-pentazatricyclo[7.3.0.02,6]dodeca-1,6,8,11-tetraen-5-one
- SMILES
- CN1C2=NC(=C3C(=C2C=N1)NN(C3=O)C4=CC=C(C=C4)F)C5=CC(=CC=C5)C(F)(F)F
- InChIKey
- WQKVVTLTCHDAST-UHFFFAOYSA-N
- InChI
- 1S/C21H13F4N5O/c1-29-19-15(10-26-29)18-16(20(31)30(28-18)14-7-5-13(22)6-8-14)17(27-19)11-3-2-4-12(9-11)21(23,24)25/h2-10,28H,1H3
- Synonyms
- 2-(4-Fluorophenyl)-6-methyl-4-(3-(trifluoromethyl)phenyl)-1,2-dihydrodipyrazolo[3,4-b:3',4'-d]pyridin-3(6H)-one | B7/...
- Tiragolumab (anti-TIGIT), INHIBITOR of T-cell immunoreceptor with Ig and ITIM domains inhibitorCAS: 1918185-84-8Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA● In Stock — US warehouse, ships to EU* Item #: Ab169250View ProductPricing & Pack Sizes
Technical Identifiers
- Associated targets
- TIGIT
- Short Overview
- Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
- Reactive species
- Cynomolgus monkey, Human, Rabbit
- Isotype
- Human IgG1
- Host species
- Human
- Conjugation
- Unconjugated
- Synonyms
- RG6058 | MTIG7192A | T cell immunoreceptor with Ig and ITIM domains | TIGIT | VSIG9 | VSTM3 | WUCAM | DKFZp667A205 an...
- Prezalumab (anti-B7-H2)CAS: 1523164-68-2Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA● In Stock — US warehouse, ships to EU* Item #: Ab170952View ProductPricing & Pack Sizes
Technical Identifiers
- Associated targets
- ICOSLG
- Short Overview
- Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG2SA; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
- Reactive species
- Cynomolgus monkey, Human, Mouse
- Isotype
- Human IgG2SA
- Host species
- Human
- Conjugation
- Unconjugated
- Synonyms
- B7 H2 antibody | B7 homolog 2 antibody | B7 homologue 2 antibody | B7 like protein Gl50 antibody | B7 related protein...
- Galiximab (anti-CD80), INHIBITOR of T-lymphocyte activation antigen CD80 inhibitorCAS: 357613-77-5Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA● In Stock — US warehouse, ships to EU* Item #: Ab177850View ProductPricing & Pack Sizes
Technical Identifiers
- Associated targets
- CD80
- Short Overview
- Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
- Reactive species
- Cynomolgus monkey, Human
- Isotype
- Human IgG1
- Host species
- Human
- Conjugation
- Unconjugated
- Synonyms
- Activation B7-1 antigen | B7 | BB1 | CTLA-4 counter-receptor B7.1
- CD80-IN-3Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%◐ .Made to order · 8–12 wks Item #: C651374View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-(6-fluoro-3-oxo-1H-pyrazolo[4,3-c]quinolin-2-yl)benzoic acid
- SMILES
- C1=CC2=C3C(=CN=C2C(=C1)F)C(=O)N(N3)C4=CC=C(C=C4)C(=O)O
- InChIKey
- NLGJRBLPUVEYKC-UHFFFAOYSA-N
- InChI
- 1S/C17H10FN3O3/c18-13-3-1-2-11-14-12(8-19-15(11)13)16(22)21(20-14)10-6-4-9(5-7-10)17(23)24/h1-8,20H,(H,23,24)
- Synonyms
- LBEWFVRAHKOLOU-UHFFFAOYSA-N | CD80-IN-3 | benzoic acid, 4-(6-fluoro-3,5-dihydro-3-oxo-2H-pyrazolo[4,3-c]quinolin-2-yl...
- Theralizumab (anti-CD28)CAS: 906068-56-2Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA● In Stock — US warehouse, ships to EU* Item #: Ab190136View ProductPricing & Pack Sizes
Technical Identifiers
- Associated targets
- CD28
- Short Overview
- Purity≥95% (SDS-PAGE&SEC); Endotoxin Level≤1.0EU/mg; Human IgG4; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
- Reactive species
- Human
- Isotype
- Human IgG4
- Host species
- Human
- Conjugation
- Unconjugated
- SMILES
- [Theralizumab]
- Synonyms
- CD 28 antibody | CD28 antibody | CD28 antigen antibody | CD28 molecule antibody | CD28_HUMAN antibody | MGC138290 ant...
- AcazicolceptCAS: 2797026-97-0◐ .Made to order · 8–12 wks Item #: A1434024View ProductPricing & Pack Sizes
Technical Identifiers
- Calcium influx inducer compound 634CAS: 882291-37-4 Formula: C15H15N3O4S3 Molecular Weight: 397.49◐ .Made to order · 8–12 wks Item #: C1433867View ProductPricing & Pack Sizes
Technical Identifiers
- FR104◐ .Made to order · 8–12 wks Item #: F1434023View ProductPricing & Pack Sizes
Technical Identifiers
- ICOS-IN-1CAS: 1006002-58-9 Formula: C17H14Cl2N2O2 Molecular Weight: 349.21◐ .Made to order · 8–12 wks Item #: I1433868View ProductPricing & Pack Sizes
Technical Identifiers
- M04CAS: 875158-73-9 Formula: C18H24N2O4S3 Molecular Weight: 428.59◐ .Made to order · 8–12 wks Item #: M1424244View ProductPricing & Pack Sizes
Technical Identifiers
- KY-1044CAS: 2489390-15-8◐ .Made to order · 8–12 wks Item #: K1434021View ProductPricing & Pack Sizes
Technical Identifiers
Fast Shipping Same-day shipping on in-stock items
Technical Details Quality & specification info on every product page
Pack Size Options Multiple packaging sizes with pricing access from listing
R&D Use Only Products supplied for research and development use
Frequently Asked Questions
How is the CD28 listing put together?
It draws on reported CD28 annotations within Immunology/Inflammation and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a CD28 modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the CD28 entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for CD28 compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For CD28 work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the CD28 compound I need is not listed?
Search by CAS number or SMILES first, since analogs of CD28 compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.