MALT1

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  1. MI 2
    CAS: 1047953-91-2 Formula: C19H17Cl3N4O3 Molecular Weight: 455.72
    ● In Stock — US warehouse, ships to EU* Item #: M276284
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    IUPAC Name
    2-chloro-N-[4-[5-(3,4-dichlorophenyl)-3-(2-methoxyethoxy)-1,2,4-triazol-1-yl]phenyl]acetamide
    SMILES
    COCCOC1=NN(C(=N1)C2=CC(=C(C=C2)Cl)Cl)C3=CC=C(C=C3)NC(=O)CCl
    InChIKey
    TWJGQZBSEMDPQP-UHFFFAOYSA-N
    InChI
    1S/C19H17Cl3N4O3/c1-28-8-9-29-19-24-18(12-2-7-15(21)16(22)10-12)26(25-19)14-5-3-13(4-6-14)23-17(27)11-20/h2-7,10H,8-9,11H2,1H3,(H,23,27)
    Synonyms
    2-Chloro-N-[4-[5-(3,4-dichlorophenyl)-3-(2-methoxyethoxy)-1H-1,2,4-triazol-1-yl]phenyl]acetamide | MI-2 (MALT1 inhibi...
  2. JNJ-67856633, Inhibitor of Janus kinase 2;Inhibitor of MALT1 paracaspase
    CAS: 2230273-76-2 Formula: C20H11F6N5O2 Molecular Weight: 467.32
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: J420001
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    IUPAC Name
    1-(1-oxo-2H-isoquinolin-5-yl)-5-(trifluoromethyl)-N-[2-(trifluoromethyl)pyridin-4-yl]pyrazole-4-carboxamide
    SMILES
    C1=CC2=C(C=CNC2=O)C(=C1)N3C(=C(C=N3)C(=O)NC4=CC(=NC=C4)C(F)(F)F)C(F)(F)F
    InChIKey
    APWRZPQBPCAXFP-UHFFFAOYSA-N
    InChI
    1S/C20H11F6N5O2/c21-19(22,23)15-8-10(4-6-27-15)30-18(33)13-9-29-31(16(13)20(24,25)26)14-3-1-2-12-11(14)5-7-28-17(12)32/h1-9H,(H,28,32)(H,27,30,33)
    Synonyms
    APWRZPQBPCAXFP-UHFFFAOYSA-N | SAFIMALTIB [INN] | safimaltib | SCHEMBL23417687 | 1-(1-Oxo-1,2-dihydro-5-isoquinolyl)-5...
  3. MI 2
    CAS: 1047953-91-2 Formula: C19H17Cl3N4O3 Molecular Weight: 455.72
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: M420460
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    Technical Identifiers
    IUPAC Name
    2-chloro-N-[4-[5-(3,4-dichlorophenyl)-3-(2-methoxyethoxy)-1,2,4-triazol-1-yl]phenyl]acetamide
    SMILES
    COCCOC1=NN(C(=N1)C2=CC(=C(C=C2)Cl)Cl)C3=CC=C(C=C3)NC(=O)CCl
    InChIKey
    TWJGQZBSEMDPQP-UHFFFAOYSA-N
    InChI
    1S/C19H17Cl3N4O3/c1-28-8-9-29-19-24-18(12-2-7-15(21)16(22)10-12)26(25-19)14-5-3-13(4-6-14)23-17(27)11-20/h2-7,10H,8-9,11H2,1H3,(H,23,27)
    Synonyms
    2-Chloro-N-[4-[5-(3,4-dichlorophenyl)-3-(2-methoxyethoxy)-1H-1,2,4-triazol-1-yl]phenyl]acetamide
  4. MLT-748
    CAS: 1832578-30-9 PubChem CID: 129072285 Formula: C19H19Cl2N9O3 Molecular Weight: 492.32
    ● In Stock — US warehouse, ships to EU* Item #: M414254
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    IUPAC Name
    1-[2-chloro-7-[(1R,2R)-1,2-dimethoxypropyl]pyrazolo[1,5-a]pyrimidin-6-yl]-3-[5-chloro-6-(triazol-2-yl)pyridin-3-yl]urea
    SMILES
    CC(C(C1=C(C=NC2=CC(=NN21)Cl)NC(=O)NC3=CC(=C(N=C3)N4N=CC=N4)Cl)OC)OC
    InChIKey
    XKQLNDPUQSZBJW-QGHHPUGFSA-N
    InChI
    1S/C19H19Cl2N9O3/c1-10(32-2)17(33-3)16-13(9-22-15-7-14(21)28-29(15)16)27-19(31)26-11-6-12(20)18(23-8-11)30-24-4-5-25-30/h4-10,17H,1-3H3,(H2,26,27,31)/show more
    Synonyms
    Urea,N-​[2-​chloro-​7-​[(1R,​2R)​-​1,​2-​dimethoxypropyl]​pyrazolo[1,​5-​a]​pyrimidin-​6-​yl]​-​N'-​[5-​chloro-​6-​(2H-...
  5. Z-VRPR-FMK(TFA)
    CAS: 1381885-28-4(free base) Formula: C31H49FN10O6 . C2HF3O2 Molecular Weight: 790.81
    Solid ≥90%
    ◐ .Made to order · 8–12 wks Item #: V275362
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    Technical Identifiers
    Synonyms
    MALT1 Inhibitor | Z-Val-Arg-Pro-DL-Arg-FMK(TFA) | VRPR
  6. MLT-943
    CAS: 1832576-04-1 PubChem CID: 118540057 Formula: C16H14ClF3N6O2 Molecular Weight: 414.77
    ◐ .Made to order · 8–12 wks Item #: M648386
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    Technical Identifiers
    IUPAC Name
    1-[2-chloro-7-[(1S)-1-methoxyethyl]pyrazolo[1,5-a]pyrimidin-6-yl]-3-[2-(trifluoromethyl)pyridin-4-yl]urea
    SMILES
    CC(C1=C(C=NC2=CC(=NN21)Cl)NC(=O)NC3=CC(=NC=C3)C(F)(F)F)OC
    InChIKey
    ZMPUACZRXUZAJD-QMMMGPOBSA-N
    InChI
    1S/C16H14ClF3N6O2/c1-8(28-2)14-10(7-22-13-6-12(17)25-26(13)14)24-15(27)23-9-3-4-21-11(5-9)16(18,19)20/h3-8H,1-2H3,(H2,21,23,24,27)/t8-/m0/s1
  7. MLT-747
    CAS: 2097853-86-4 PubChem CID: 129117094 Formula: C20H21Cl2N7O3 Molecular Weight: 478.33
    ◐ .Made to order · 8–12 wks Item #: M647585
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    Technical Identifiers
    IUPAC Name
    1-[2-chloro-7-[(1S)-1-methoxyethyl]pyrazolo[1,5-a]pyrimidin-6-yl]-3-[5-chloro-6-(pyrrolidine-1-carbonyl)pyridin-3-yl]urea
    SMILES
    CC(C1=C(C=NC2=CC(=NN21)Cl)NC(=O)NC3=CC(=C(N=C3)C(=O)N4CCCC4)Cl)OC
    InChIKey
    OJTGJRAKRGEDPI-NSHDSACASA-N
    InChI
    1S/C20H21Cl2N7O3/c1-11(32-2)18-14(10-23-16-8-15(22)27-29(16)18)26-20(31)25-12-7-13(21)17(24-9-12)19(30)28-5-3-4-6-28/h7-11H,3-6H2,1-2H3,(H2,25,26,31)/show more
  8. Mepazine hydrochloride
    CAS: 2975-36-2 EC Number: 221-020-8 PubChem CID: 102907 Formula: C19H23ClN2S Molecular Weight: 346.92
    ◐ .Made to order · 8–12 wks Item #: M651959
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    Technical Identifiers
    IUPAC Name
    10-[(1-methylpiperidin-3-yl)methyl]phenothiazine;hydrochloride
    SMILES
    CN1CCCC(C1)CN2C3=CC=CC=C3SC4=CC=CC=C42.Cl
    InChIKey
    RLCFKYRNUBRPIK-UHFFFAOYSA-N
    InChI
    1S/C19H22N2S.ClH/c1-20-12-6-7-15(13-20)14-21-16-8-2-4-10-18(16)22-19-11-5-3-9-17(19)21;/h2-5,8-11,15H,6-7,12-14H2,1H3;1H
    Synonyms
    BENZOTHIAZOLE, 1-(P-AMINOPHENYL)-5-METHYL- | NSC64076 | NSC-64076 | Q27289984 | (Acetyloxy)(5-nitro-2-furyl)methyl ac...
  9. Mepazine, Mucosa-associated lymphoid tissue lymphoma translocation protein 1 inhibitor
    CAS: 60-89-9 Formula: C19H22N2S Molecular Weight: 310.46
    Liquid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Made to order · 8–12 wks Item #: M668738
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    Technical Identifiers
    IUPAC Name
    10-[(1-methylpiperidin-3-yl)methyl]phenothiazine
    SMILES
    CN1CCCC(C1)CN2C3=CC=CC=C3SC4=CC=CC=C42
    InChIKey
    CBHCDHNUZWWAPP-UHFFFAOYSA-N
    InChI
    1S/C19H22N2S/c1-20-12-6-7-15(13-20)14-21-16-8-2-4-10-18(16)22-19-11-5-3-9-17(19)21/h2-5,8-11,15H,6-7,12-14H2,1H3
    Synonyms
    Pacatal Base | Lacumin | MEPAZINE | Mepazine Base | Pakatal | mepasin | MPMP | CAS-60-89-9 | Pacatal | Paxital | (N-M...
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R&D Use Only Products supplied for research and development use

Frequently Asked Questions

What can I find under MALT1?
This listing collects compounds associated with MALT1 within our NF-κB area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.
What should I consider when picking a compound for MALT1?
Consider the reported potency of each MALT1 compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.
What quality information is provided for MALT1 compounds?
Each MALT1 product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search MALT1 compounds by activity or structure?
Yes. Filter the MALT1 listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].

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