Methyl palmitate - ≥99%(GC) , CAS No.112-39-0

CAS: 112-39-0 Cat. No.: M109448 Formula: C₁₇H₃₄O₂ Molecular Weight: 270.45 Beilstein Registry Number: 1780973 EC Number: 203-966-3

GRADE & PURITY ≥99%(GC)

Synonyms

Methyl palmitic acid|Palmitic acid methyl ester|Metholene 2216|C16 FAME|METHYL PALMITATE [HSDB]|Hexadecanoic acid methyl ester (FAME MIX)|METHYL PALMITATE (USP-RS)|DUB PM COS|Methyl hexadecanoate|WE(1:0/16:0)|AEC METHYL PALMITATE|Hexadecanoic acid, methyl ester|Hexadecanoate methyl ester|Radia 7120|Hexadecanoic acid methyl ester|Emery 2216|n-Hexadecanoic acid methyl ester|METHYL PALMITATE [USP-RS]|Palmitic acid, methyl ester|METHYL PALMITATE [INCI]|palmitic methyl ester|a methylhexadecanoic acid|Methyl n-hexadecanoate|formyl hexadecanoate|METHYL PALMITATE|methyl hexadecanoic acid|Tert-Butyl3-(N-Hydroxycarbamimidoyl)piperidine-1-carboxylate

Storage

Room temperature

Shipped In

Normal

Overview

Methyl palmitate (PAME), a fatty acid ester of palmitic acid, is a glucose-receptor antagonist. Methyl palmitate acts as a vasodilator and relaits arterioles in the retina during electrical depolarization. In the upper cervical ganglion, methyl palmitate regulates nicotinic receptors. Endogenous methyl palmitate modulates nicotine-receptor mediated signaling in the upper cervical ganglion. PAME activates the Kv7 channel and promotes perivascular adipose tissue.

Application：

Using laser Doppler flowmeter (LDF) experiments, researchers have tested the effects of methyl palmitate on cerebral blood flow and used it as a standard to determine the retention index (RI) of a gas chromatography-mass spectrometer.

Specifications

Synonyms

Methyl palmitic acid | Palmitic acid methyl ester | Metholene 2216 | C16 FAME | METHYL PALMITATE [HSDB] | Hexadecanoic acid methyl ester (FAME MIX) | METHYL PALMITATE (USP-RS) | DUB PM COS | Methyl hexadecanoate | WE(1:0/16:0) | AEC METHYL PALMITATE | Hexadecanoic acid, methyl ester | Hexadecanoate methyl ester | Radia 7120 | Hexadecanoic Show more

Specifications & Purity

≥99%(GC)

Biochemical and Physiological Mechanisms

Methyl palmitate has anti-inflammatory and antifibrotic effects. Methyl palmitate prevents bleomycin-induced pulmonary inflammation and fibrosis in rats by inhibiting NF-κB. Methyl palmitate also prevents CCL4-induced liver fibrosis associated with TGF-β

Storage

Room temperature

Shipped In

Normal

Purity

≥99%(GC)

Product Line

M109448-5g

Names and Identifiers

Pubchem Sid

504751617

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504751617

Canonical Smiles

CCCCCCCCCCCCCCCC(=O)OC

IUPAC Name

methyl hexadecanoate

InChIKey

FLIACVVOZYBSBS-UHFFFAOYSA-N

INCHI

1S/C17H34O2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17(18)19-2/h3-16H2,1-2H3

Isomeric SMILES

CCCCCCCCCCCCCCCC(=O)OC

WGK Germany

1

Molecular Weight

270.45

Beilstein

1780973

Reaxy-Rn

1780973

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1780973&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lipids and lipid-like molecules
    • Class Fatty Acyls
      • Subclass Fatty acid esters

• Kingdom: Organic compounds
• Superclass: Lipids and lipid-like molecules
• Class: Fatty Acyls
• Subclass: Fatty acid esters
• Intermediate Tree Nodes: Not available
• Direct Parent: Fatty acid methyl esters
• Alternative Parents: Methyl esters Monocarboxylic acids and derivatives Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Fatty acid methyl ester - Methyl ester - Carboxylic acid ester - Monocarboxylic acid or derivatives - Carboxylic acid derivative - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as fatty acid methyl esters. These are compounds containing a fatty acid that is esterified with a methyl group. They have the general structure RC(=O)OR', where R=fatty aliphatic tail or organyl group and R'=methyl group.
• External Descriptors: Wax monoesters

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

CNR1 Tclin Cannabinoid CB1 receptor (20913 Activities)

Discover Target: CNR1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CNR2 Tchem Cannabinoid CB2 receptor (16942 Activities)

Discover Target: CNR2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PSMB2 Tclin Proteasome Macropain subunit (1025 Activities)

Discover Target: PSMB2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Faah Anandamide amidohydrolase (3907 Activities)

Discover Target: Faah

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PRE2 Proteasome Macropain subunit PRE2 (43 Activities)

Discover Target: PRE2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PRE7 Proteasome component C5 (37 Activities)

Discover Target: PRE7

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Chemical and Physical Properties

• Solubility: Easily soluble in alcohol, acetone, chloroform, and benzene, soluble in ether, insoluble in water.
• x_refractive_index: 1.4512
• x_flash_point_drop_fahrenheit: 235.4 °F
• x_flash_point_drop_centigrade: >110℃
• x_boil_point_char: 185°C
• x_melt_point_char: 28°C
• Molecular Weight: 270.500 g/mol
• XLogP3: 7.900
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 15
• Exact Mass: 270.256 Da
• Monoisotopic Mass: 270.256 Da
• Topological Polar Surface Area: 26.300 Ų
• Heavy Atom Count: 19
• Formal Charge: 0
• Complexity: 190.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Frequently Asked Questions

What is the purity of this product, and how is it determined?

This product is supplied at ≥99% purity, determined by gas chromatography (GC). Lot-specific values are stated on the Certificate of Analysis.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 112-39-0, the molecular formula is C17H34O2, and the molecular weight is 270.45 g/mol. InChIKey FLIACVVOZYBSBS-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.