Monoolein - Moligand™, ≥95% , Agonist of GPR119, CAS No.111-03-5, Agonist of GPR119

CAS: 111-03-5 Cat. No.: M395915 Molecular Weight: 356.54 Beilstein Registry Number: 1728976 EC Number: 203-827-7
AVAILABLE TO ORDER
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
Synonyms
1-Oleylglycerol | alpha-Monoolein | Excel O 95F | Oleoyl glycerol | 1-Monooleoyl-rac-glycerol | CHEBI:75342 | Emery oleic acid ester 2221 | Nikkol MGO | rac-1-Monoolein | Monoolein | mono-olein | 1,2,3-Propanetriol mono((Z)-9-octadecenoate) | 2,3-dihydrox
Storage
Store at -20°C,Argon charged
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
100mg
M395915-100mg
2
$117.90
500mg
M395915-500mg
1
$329.90
Enter a quantity for the sizes you want to add.
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Why this grade

Moligand™, ≥95% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -20°C,Argon charged Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 20 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

1-Oleoyl-rac-glycerol is a monoglyceride, obtained from natural oils and fats. It contains two alcohol groups that are reactive. It is soluble in chloroform and hexane. It can be crystallized from hexane.

Specifications

Synonyms
1-Oleylglycerol | alpha-Monoolein | Excel O 95F | Oleoyl glycerol | 1-Monooleoyl-rac-glycerol | CHEBI:75342 | Emery oleic acid ester 2221 | Nikkol MGO | rac-1-Monoolein | Monoolein | mono-olein | 1, 2, 3-Propanetriol mono((Z)-9-octadecenoate) | 2, 3-dihydrox
Specifications & Purity
Moligand™, ≥95%
Biochemical and Physiological Mechanisms
1-Oleoyl-rac-glycerol shows both inhibition and anti-inhibition action on the lipoprotein lipase mediated triglyceride hydrolysis.
Storage
Store at -20°C, Argon charged
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Action Type
AGONIST
Mechanism of action
Agonist of GPR119
Purity
≥95%
Names and Identifiers
Canonical SmilesCCCCCCCCC=CCCCCCCCC(=O)OCC(CO)O
IUPAC Name2,3-dihydroxypropyl (Z)-octadec-9-enoate
InChIKeyRZRNAYUHWVFMIP-KTKRTIGZSA-N
INCHI1S/C21H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-19-20(23)18-22/h9-10,20,22-23H,2-8,11-19H2,1H3/b10-9-
Isomeric SMILES CCCCCCCC/C=C\CCCCCCCC(=O)OCC(CO)O
WGK Germany 1
Molecular Weight 356.54
Beilstein 1728976
Reaxy-Rn 1728976
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1728976&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassLipids and lipid-like molecules
ClassGlycerolipids
SubclassMonoradylglycerols
Intermediate Tree Nodes Monoacylglycerols
Direct Parent1-monoacylglycerols
Alternative Parents Fatty acid esters  Secondary alcohols  Carboxylic acid esters  1,2-diols  Monocarboxylic acids and derivatives  Primary alcohols  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAliphatic acyclic compounds
Substituents 1-acyl-sn-glycerol - Fatty acid ester - Fatty acyl - 1,2-diol - Carboxylic acid ester - Secondary alcohol - Carboxylic acid derivative - Monocarboxylic acid or derivatives - Primary alcohol - Hydrocarbon derivative - Organic oxygen compound - Carbonyl group - Alcohol - Organic oxide - Organooxygen compound - Aliphatic acyclic compound
DescriptionThis compound belongs to the class of organic compounds known as 1-monoacylglycerols. These are monoacylglycerols containing a glycerol acylated at the 1-position.
External Descriptors Monoacylglycerols
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
GPR119 Tclin Glucose-dependent insulinotropic receptor (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PTGS2 Tclin Cyclooxygenase-2 (13999 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PLA2G2A Tchem Phospholipase A2 group IIA (1079 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

11 results found

Lot NumberCertificate TypeDateItem
A2627545Certificate of AnalysisJan 19, 2026 M395915
A2627546Certificate of AnalysisJan 19, 2026 M395915
G2516376Certificate of AnalysisJul 12, 2025 M395915
G2516378Certificate of AnalysisJul 12, 2025 M395915
G2516384Certificate of AnalysisJul 12, 2025 M395915
G2516385Certificate of AnalysisJul 12, 2025 M395915
K2511021Certificate of AnalysisJul 12, 2025 M395915
H2111380Certificate of AnalysisMay 12, 2025 M395915
H2111381Certificate of AnalysisMay 12, 2025 M395915
K2212281Certificate of AnalysisAug 16, 2022 M395915
K2212283Certificate of AnalysisAug 16, 2022 M395915

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Chemical and Physical Properties
Sensitivitylight sensitive;air sensitive ;Moisture sensitive.
Flash Point(°F)309.2 °F
Flash Point(°C)154 °C
Melt Point(°C)35-37°C
Molecular Weight356.500 g/mol
XLogP36.500
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count19
Exact Mass356.293 Da
Monoisotopic Mass356.293 Da
Topological Polar Surface Area66.800 Ų
Heavy Atom Count25
Formal Charge0
Complexity315.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds1
Covalently-Bonded Unit Count1
Citations of This Product
References
1. Yingzhu Zhang, Jinqi Xu, Cuie Tang, Yan Li.  (2023)  Crystallization Behavior and Physical Properties of Monoglycerides-Based Oleogels as Function of Oleogelator Concentration.  Foods,  12  (2): (345).  [PMID:36673437] [10.3390/foods12020345]
2. Qingqing Xu, Xiaoli Qin, Dongming Lan, Xuan Liu, Bo Yang, Sentai Liao, Weifei Wang, Yonghua Wang.  (2022)  Water-in-oil emulsions enriched with alpha-linolenic acid in diacylglycerol form: Stability, formation mechanism and in vitro digestion analysis.  FOOD CHEMISTRY,      [PMID:35609461] [10.1016/j.foodchem.2022.133201]
3. Fu Fangqin, Li Xin, Zheng Tengyi, Xia Xiao, Du Minqun, Huang Zhengwei, Huang Ying, Pan Xin, Wu Chuanbin.  (2021)  Stability Evaluation of Lyotropic Liquid Crystalline Precursor for the Co-delivery of Chlorhexidine and Silver Nanoparticles.  AAPS PHARMSCITECH,  22  (7): (1-9).  [PMID:34545436] [10.1208/s12249-021-02102-x]
4. Weiwei Wang, Zhuangzhuang Liu, Qimin Song, Xindi Zhang, Shengkai Jiao, Yao Xu, Quanda Xu, Dezun Sheng.  (2021)  Tribological performance of organic molybdenum in the presence of organic friction modifier.  PLoS One,  16  (6): (e0252203).  [PMID:34111128] [10.1371/journal.pone.0252203]
5. Yajing Hu, Zhenxia Du, Xuechun Sun, Xin Ma, Jingdan Song, Haixia Sui, Augustine Atta Debrah.  (2020)  Non-targeted analysis and risk assessment of non-volatile compounds in polyamide food contact materials.  FOOD CHEMISTRY,      [PMID:33601649] [10.1016/j.foodchem.2020.128625]
6. Xiao-Wei Chen, Shang-De Sun, Guo-Long Yang, Chuan-Guo Ma.  (2019)  Engineering phytosterol-based oleogels for potential application as sustainable petrolatum replacement.  RSC Advances,  10  (1): (244-252).  [PMID:35492564] [10.1039/C9RA06950J]
7. Shangde Sun, Xuebei Hou.  (2019)  A novel caffeic acid-based deep eutectic solvent as caffeoyl donor to enhance glycerol caffeates synthesis.  JOURNAL OF MOLECULAR LIQUIDS,      [PMID:] [10.1016/j.molliq.2018.12.145]
8. Tengyi Zheng, Xintian Huang, Jintian Chen, Disang Feng, Liling Mei, Ying Huang, Guilan Quan, Chune Zhu, Vikramjeet Singh, Hao Ran, Xin Pan, Chuan-Yu Wu, Chuanbin Wu.  (2018)  A liquid crystalline precursor incorporating chlorhexidine acetate and silver nanoparticles for root canal disinfection.  Biomaterials Science,  (3): (596-603).  [PMID:29406548] [10.1039/C7BM00764G]
9. Han Lidong, Yang Rong, Yuan Shengxiao, Ding Shuang, Wu Ziheng, Wu Zhenghong, Qi Xiaole.  (2018)  Soft multiple emulsions demonstrating reversible freeze-thawing capacity and enhanced skin permeability of diclofenac sodium.  COLLOID AND POLYMER SCIENCE,  296  (3): (471-481).  [PMID:] [10.1007/s00396-018-4265-3]
10. Xuan Liu, Chunjin Huang, Dongming Lan, Weifei Wang, Yonghua Wang.  (2024)  Combining phospholipase A1 with monoacylglycerol lipase for crude vegetable oil degumming through improved oil-water separation.  FOOD CHEMISTRY,      [PMID:39644657] [10.1016/j.foodchem.2024.142366]
11. Siliang Ding, Xiaohan Chen, Bo Ouyang, Bo Yang, Weifei Wang, Yonghua Wang.  (2024)  Exploring Diacylglycerol Oil-Based Oleogels as Effective Stabilizers in Peanut Butter: Performance, Structural Insights, and Sensory Evaluation.  Journal of Oleo Science,      [PMID:38311404] [10.5650/jos.ess23122]
12. Ruirui Li, Wei Zhuang, Yan Gao, Yahan Bai, Keke Zhang, Zhenfu Wang.  (2024)  Interfacial modulation of hierarchically porous UIO-66 for the immobilization of Rhizomucor miehei lipase towards the efficient synthesis of 1,3-dioleic acid glycerol.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:39710037] [10.1016/j.ijbiomac.2024.138993]
13. Bowen Yang, Tian Zhao, Shengyang Ji, Yan Liu, Minghao Xu, Baiyi Lu.  (2024)  Molecular dynamics simulations of the interfacial behaviors and photo-oxidation of phytosterol under different emulsion oil content.  FOOD CHEMISTRY,      [PMID:38663239] [10.1016/j.foodchem.2024.139292]
14. Huijing Chen, Shanliang Zhong, Guoxiang Chi, Huiying Li, Kewei Chen, Zhirong Wang, Jianquan Kan.  (2025)  Preparation and functional characteristics of starch-lipid complexes with different oleic acid-rich glycerolipids.  FOOD CHEMISTRY,      [PMID:39986078] [10.1016/j.foodchem.2025.143450]
15. Binke Wang, Xinyu Qi, Ruping Yang, Xu Xu, Shiyao Li, Chunli Zhang, Haitao Yu.  (2025)  Cubosome-based co-delivery of doxorubicin and polydatin for targeted cancer therapy.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.168855]
16. Huijing Chen, Qi Zhao, Guoxiang Chi, Kewei Chen, Zhirong Wang, Jianquan Kan.  (2025)  Effects of the oleic acid-rich glycerolipids and thermal-mechanical treatment on the functionality of wheat gluten: Multi-spectroscopy and molecular simulation analysis.  FOOD CHEMISTRY,      [PMID:40279899] [10.1016/j.foodchem.2025.144472]
17. Yongxin Li, Wenni Tian, Fang Tian, Yanrong Zhao, Xuguang Zhang, Jie Xiao.  (2025)  Spatiotemporally programmed co-delivery via double emulsions enables absorption synergy of 5-MTHF-ca and vitamin D3.  FOOD RESEARCH INTERNATIONAL,      [PMID:40597517] [10.1016/j.foodres.2025.116800]
18. Yanru Bao, Jiawei Li, Hanhao Qin, Shuning Yuan, Hao Jiang.  (2025)  Glyceride-modulated starch-based emulsion gels with enhanced structural precision for texture-controlled 3D printed dysphagia foods.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:41482229] [10.1016/j.ijbiomac.2025.149979]
19. Huijing Chen, Qi Zhao, Guoxiang Chi, Zhirong Wang, Jianquan Kan.  (2026)  Multi-spectroscopy and molecular simulation reveal the interaction of oleic glycerolipids modified wheat dough induced by thermomechanical treatment.  FOOD CHEMISTRY,      [PMID:41764825] [10.1016/j.foodchem.2026.148650]
20. Huijing Chen, Guoxiang Chi, Xiaowei Peng, Zhirong Wang, Jianquan Kan.  (2026)  Structural and physicochemical properties of thermo-mechanical combined lipid modified wheat starches and their application in model dough.  FOOD CHEMISTRY,      [PMID:] [10.1016/j.foodchem.2026.148974]
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