Monosodium urate (PBS solution) - 2 wt% , CAS No.1198-77-2

CAS: 1198-77-2 Cat. No.: M276559 Molecular Weight: 190.09
AVAILABLE TO ORDER
GRADE & PURITY 2 wt%
Synonyms
NCGC00181049-01 | AS-80123 | Uric acid sodium salt | Uric acid monosodium salt (crystals) | Monosodium urate (crystals) | CID 16220071 | SCHEMBL229866
Storage
Store at -20°C,Desiccated
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
10mg
M276559-10mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$69.90
Enter a quantity for the sizes you want to add.
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Why this grade

2 wt% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C,Desiccated Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 8 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

The product is a PBS solution, packaged based on solute content. Shake evenly before use.

Specifications

Synonyms
NCGC00181049-01 | AS-80123 | Uric acid sodium salt | Uric acid monosodium salt (crystals) | Monosodium urate (crystals) | CID 16220071 | SCHEMBL229866
Specifications & Purity
2 wt%
Biochemical and Physiological Mechanisms
NLRP3/NALP3 inflammasome activator. Stimulates caspase-1 activating NLRP3/NALP3 inflammasome, results in active IL-1β and IL-18 production. Active in vitro and in vivo .
Storage
Store at -20°C, Desiccated
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Note
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Names and Identifiers
Canonical SmilesC12=C(NC(=O)N1)NC(=O)NC2=O.[Na]
InChIKeyXDKLKFULWJYRCB-UHFFFAOYSA-N
INCHI1S/C5H4N4O3.Na/c10-3-1-2(7-4(11)6-1)8-5(12)9-3;/h(H4,6,7,8,9,10,11,12);
Isomeric SMILES C12=C(NC(=O)N1)NC(=O)NC2=O.[Na]
Molecular Weight 190.09
Reaxy-Rn 24218033
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=24218033&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

3D Structure
Interactive Chemical Structure Model





Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

1 results found

Lot NumberCertificate TypeDateItem
E2622081Certificate of AnalysisJun 02, 2026 M276559
Documents & Articles
Citations of This Product
References
1. Jiang Yanan, Zhang Chengyi, Zhang Xinyue, Lan Na, Zhao Zihan, Xv Yawei, Wang Qi, Wang Siwei, Chen Baifeng, Chen Xi, Wang Yilin.  (2024)  Antigout effects and mechanisms of total flavonoids from prunus tomentosa.  TECHNOLOGY AND HEALTH CARE,      [PMID:38759051] [10.3233/THC-248019]
2. Du Li, Jindian Dong, Tong Xiong, Xingyu Zhou, Yanhui Li, Chuncheng Chen, Shijie Li, Zhuoyue Song, Nenggui Xu, Mingjing Yang, Xiaoxia Yan, Tao Liu, Shihui Liu.  (2024)  Transdermal delivery of iguratimod and colchicine ethosome by dissolving microneedle patch for the treatment of recurrent gout.  COLLOIDS AND SURFACES B-BIOINTERFACES,      [PMID:39003846] [10.1016/j.colsurfb.2024.114087]
3. Yu Dong-hua, Wang Yu, Yu Chun-Miao, Zhou Qi, Liu Shu-min, Liu Ting-ting.  (2025)  Construction of ceRNA networks in joint tissues of gouty arthritis rats based on transcriptome sequencing.  AIP Advances,  15  (7):   [PMID:] [10.1063/5.0271292]
4. Xiaomin Xu, Donghua Yu, Yu Wang, Peng Xu, Xin Jiang, Fang Lu, Shumin Liu.  (2024)  Integrating network pharmacology and renal metabonomics to reveal the protective mechanism of resveratrol on gouty nephropathy.  BIOMEDICAL CHROMATOGRAPHY,      [PMID:38402638] [10.1002/bmc.5839]
5. Xiaomin Xu, Donghua Yu, Yu Wang, Xin Jiang, Fang Lu, Shumin Liu.  (2024)  Investigating the mechanisms of resveratrol in the treatment of gouty arthritis through the integration of network pharmacology and metabolics.  Frontiers in Endocrinology,      [PMID:39534253] [10.3389/fendo.2024.1438405]
6. Wenyan Guo, Yi Yang, Guangyuan Liu, Jiaojiao Zhao, Yuyu Zhang, Yahui Li, Bingkun Yang, Xiaoque Zhu, Dandan Li, Xia Qin, Panpan Zhang, Zuxiao Yang, Wei Guo, Dezhi Kong, Wei Zhang.  (2025)  The Anti-Neuroinflammatory Effects of Cepharanthine in Uric Acid-Induced Neuroinflammation.  JOURNAL OF ETHNOPHARMACOLOGY,      [PMID:39870338] [10.1016/j.jep.2025.119409]
7. Wei Zhang, Xiangbing Wu, Wenming Li, Haifeng Zhang, Yijun Wang, Jing Xu, Wenhao Li, Yi Qin, Zebin Wu, Gaoran Ge, Shujun Lv, Lu Mao, Liangliang Wang, Dechun Geng.  (2025)  Pinosylvin Inhibits Inflammatory and Osteoclastogenesis via NLRP3 Inflammasome.  Advanced Science,      [PMID:40492417] [10.1002/advs.202501532]
8. Na Wang, Puchen Zhao, Qin Yin, Lizi Li, Haiqi Xu, Can Yang, Yanbei Tu, Yanfang Li.  (2025)  Shi Wei Ru Xiang pill alleviates acute gouty arthritis through suppressing NLRP3 inflammasome activation.  Frontiers in Pharmacology,      [PMID:40635741] [10.3389/fphar.2025.1595578]
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