MPP hydrochloride - ≥99% , CAS No.M659049

CAS: M659049 Cat. No.: M659049 Formula: C₂₉H₃₂ClN₃O₃ Molecular Weight: 506.04

GRADE & PURITY ≥99%

Storage

Store at 2-8°C,Desiccated

Shipped In

Wet ice

Overview

MPP hydrochloride is a potent and selective ER (estrogen receptor) modulator. MPP hydrochloride induces significant apoptosis in the endometrial cancer and oLE cell lines. MPP hydrochloride reverses the the positive effects of beta-estradiol . MPP hydroch

Appearance:Solid

IC50& Target:ERα ERβ

In Vitro:MPP (1, 5, 10, 25, 50 and 100 µM; 24 h) decreases cell viability with an IC 50 value of 20.01 µM in RL95-2 cells. MPP dihydrochloride shows antiproliferative activity at a concentration of 10 μM in RL95-2 cells. MPP dihydrochloride (20 µM; 24 h)

In Vivo:MPP (Low dose 20 μg/kg body weight or high dose 200 μg/kg body weight) leads to a dose-dependent attenuation of percent prepulse inhibition (PPI). MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal

Biological Activity:MPP hydrochloride is a potent and selective ER (estrogen receptor) modulator. MPP hydrochloride induces significant apoptosis in the endometrial cancer and oLE cell lines. MPP hydrochloride reverses the the positive effects of beta-estradiol . MPP hydroch

Specifications

Specifications & Purity

≥99%

Storage

Store at 2-8°C,Desiccated

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

MODULATOR

Purity

≥99%

Names and Identifiers

Molecular Weight

506.04

Chemical and Physical Properties

• Solubility: DMSO : 250 mg/mL (494.03 mM; Need ultrasonic)

Frequently Asked Questions

How should this product be stored?

Store at 2–8 °C, desiccated. Keep the container tightly closed with desiccant — the material is moisture-sensitive.

How is this product shipped?

This product ships chilled on wet ice. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is M659049, the molecular formula is C29H32ClN3O3, and the molecular weight is 506.04 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

What is the purity of this product?

This product is supplied at ≥99% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.