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· · COA & SDS available for every product · Same-day shipping on in-stock items NGI 1 - ≥98%(HPLC) , CAS No.790702-57-7
Synonyms
5-[(Dimethylamino)sulfonyl]-N-(5-methyl-2-thiazolyl)-2-(1-pyrrolidinyl)benzamide | NCGC00351072-01 | KSC-367-096-1 | KUC113535N-02 | ZB1632 | HY-117383 | NGI1 | NGI-1 | HMS3081P23 | EX-A2753 | NGI 1 | s8750 | KUC113535N | BN164083 | NGI1; NGI 1; ML414; ML
Shipped In
Ice chest + Ice pads
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Why this grade ≥98%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview Description：
NGI-1 is a a cell-permeable inhibitor of oligosaccharyltransferase (OST).can effectively reduce virus infectivity without affecting cell viability.
Specifications Synonyms
5-[(Dimethylamino)sulfonyl]-N-(5-methyl-2-thiazolyl)-2-(1-pyrrolidinyl)benzamide | NCGC00351072-01 | KSC-367-096-1 | KUC113535N-02 | ZB1632 | HY-117383 | NGI1 | NGI-1 | HMS3081P23 | EX-A2753 | NGI 1 | s8750 | KUC113535N | BN164083 | NGI1; NGI 1; ML414; ML
Specifications & Purity
≥98%(HPLC)
Biochemical and Physiological Mechanisms
Oligosaccharyltransferase (OST) inhibitor; anti-flaviviral. Inhibits dengue, Zika, West Nile, and yellow fever viruses by blocking viral RNA replication (EC50values are 0.85 and 2.2 μM for DENV and ZIKV inhibition, respectively). Selectively arrests proli
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Names and Identifiers Pubchem Sid 504760759 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504760759 Canonical Smiles CC1=CN=C(S1)NC(=O)C2=C(C=CC(=C2)S(=O)(=O)N(C)C)N3CCCC3 IUPAC Name 5-(dimethylsulfamoyl)-N-(5-methyl-1,3-thiazol-2-yl)-2-pyrrolidin-1-ylbenzamide InChIKey QPKGRLIYJGBKJL-UHFFFAOYSA-N INCHI 1S/C17H22N4O3S2/c1-12-11-18-17(25-12)19-16(22)14-10-13(26(23,24)20(2)3)6-7-15(14)21-8-4-5-9-21/h6-7,10-11H,4-5,8-9H2,1-3H3,(H,18,19,22) Isomeric SMILES CC1=CN=C(S1)NC(=O)C2=C(C=CC(=C2)S(=O)(=O)N(C)C)N3CCCC3 Molecular Weight 394.51 Reaxy-Rn 30750555 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=30750555&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Class Pyrrolidines Subclass Phenylpyrrolidines Intermediate Tree Nodes Not available Direct Parent Phenylpyrrolidines Alternative Parents Aminobenzenesulfonamides Aminobenzoic acids and derivatives Anthranilamides Benzenesulfonyl compounds Aniline and substituted anilines Benzoyl derivatives Dialkylarylamines 2,5-disubstituted thiazoles Organosulfonamides Heteroaromatic compounds Vinylogous amides Pyrroles Aminosulfonyl compounds Amino acids and derivatives Secondary carboxylic acid amides Azacyclic compounds Hydrocarbon derivatives Organic oxides Organooxygen compounds Organopnictogen compounds Molecular Framework Aromatic heteromonocyclic compounds Substituents Aminobenzenesulfonamide - 1-phenylpyrrolidine - Anthranilamide - Aminobenzoic acid or derivatives - Benzenesulfonamide - Benzamide - Benzenesulfonyl group - Benzoic acid or derivatives - Benzoyl - Tertiary aliphatic/aromatic amine - Dialkylarylamine - Aniline or substituted anilines - 2,5-disubstituted 1,3-thiazole - Benzenoid - Monocyclic benzene moiety - Organosulfonic acid amide - Aminosulfonyl compound - Thiazole - Azole - Vinylogous amide - Heteroaromatic compound - Pyrrole - Sulfonyl - Organosulfonic acid or derivatives - Organic sulfonic acid or derivatives - Secondary carboxylic acid amide - Amino acid or derivatives - Carboxamide group - Tertiary amine - Carboxylic acid derivative - Azacycle - Amine - Organic oxide - Hydrocarbon derivative - Organopnictogen compound - Organonitrogen compound - Organic oxygen compound - Organooxygen compound - Organosulfur compound - Organic nitrogen compound - Aromatic heteromonocyclic compound Description This compound belongs to the class of organic compounds known as phenylpyrrolidines. These are polycyclic aromatic compounds containing a benzene ring linked to a pyrrolidine ring through a CC or CN bond. Pyrrolidine is a five-membered saturated aliphatic heterocycle with one nitrogen atom and four carbon atoms. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 39.45, Max Conc. mM: 100 Molecular Weight 394.500 g/mol XLogP3 2.300 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 7 Rotatable Bond Count 5 Exact Mass 394.113 Da Monoisotopic Mass 394.113 Da Topological Polar Surface Area 119.000 Ų Heavy Atom Count 26 Formal Charge 0 Complexity 602.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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