≥97% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
OSMI-4 OSMI-4 is an inhibitor of O-GlcNAc transferase (OGT) with EC50 of 3 μM in cells.
Targets
OGT (Cell-free assay) 3 μM(EC50)
In vitro
OSMI-4 reduces O-GlcNAc levels almost completely by 5 μM. A decrease in HCF-1 cleavage products and the appearance of uncleaved HCF-1 is observed in cells treated with OSMI-4. OSMI-4 is a kind of structure-based evolution of small molecule OGT inhibitors with low nanomolar binding affinities. OSMI-4 exhibits a ~3 μM EC50 in cells, making it especially attractive for probing OGT’s complex biology.
Cell Research(from reference)
Cell lines：HEK293T cells
Concentrations：5 μM, 10 μM, 20 μM
Incubation Time：2 h, 8 h, 16 h, 24 h
Comprehensive hazard, handling, storage, and regulatory compliance document.
<<<<<<< HEAD Download SDS → ======= Download SDS → >>>>>>> release248-p3Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 G2304777 | Certificate of Analysis | Apr 03, 2026 | O414263 |
| G2304778 | Certificate of Analysis | Apr 03, 2026 | O414263 |
| G2304779 | Certificate of Analysis | Apr 03, 2026 | O414263 |
| G2304780 | Certificate of Analysis | Apr 03, 2026 | O414263 |
| G2304781 | Certificate of Analysis | Apr 03, 2026 | O414263 |
| G2304782 | Certificate of Analysis | Apr 03, 2026 | O414263 |
| G2304783 | Certificate of Analysis | Apr 03, 2026 | O414263 |
| G2304784 | Certificate of Analysis | Apr 03, 2026 | O414263 |
| G2304785 | Certificate of Analysis | Apr 03, 2026 | O414263 |
| G2304786 | Certificate of Analysis | Apr 03, 2026 | O414263 |
| G2304787 | Certificate of Analysis | Apr 03, 2026 | O414263 |
| G2304788 | Certificate of Analysis | Apr 03, 2026 | O414263 |
| G2304789 | Certificate of Analysis | Apr 03, 2026 | O414263 |
| G2304790 | Certificate of Analysis | Apr 03, 2026 | O414263 |
| H2527086 | Certificate of Analysis | May 22, 2023 | O414263 |
| Solubility | Solubility (25°C) In vitro DMSO: 100 mg/mL (165.53 mM); Water: Insoluble; Ethanol: Insoluble; |
|---|---|
| dmso_mg_max_solubility | 100 |
| dmso_mM_max_solubility | 165.538247612111 |
| water_mg_max_solubility | ＜1 |
