P110 TFA - 10mM in DMSO , CAS No.P110(DMSO)

CAS: P110(DMSO) Cat. No.: P580476 Formula: C₁₀₀H₁₇₉N₄₅O₂₅(free) Molecular Weight: 2411.78(free)

GRADE & PURITY 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Information

P110 P110 is a dynamin-related protein 1 (Drp1) -specific inhibitor that binds directly to Drp1.

Targets

Drp1

In vitro

P110 is a Drp1-specific inhibitor that binds directly to Drp1. In some cases, this binding inhibits translocation to the mitochondria or prevents mitochondrial docking.

In vivo

P110 treatment inhibits the interaction of fission proteins Fis1/Drp1, decreases mitochondrial fission, and improves bioenergetics in three different rat models of IR, including primary cardiomyocytes, ex vivo heart model, and an in vivo myocardial infarction model.

Cell Research(from reference)

Cell lines：Primary cardiac myocytes 

Concentrations：1 μmol/L 

Incubation Time：2h + 2 to 60 min 

Specifications

Specifications & Purity

10mM in DMSO

Biochemical and Physiological Mechanisms

P110 is a dynamin-related protein 1 (Drp1)-specific inhibitor that binds directly to Drp1.

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

• Molecular Weight: 2411.78(free)

Chemical and Physical Properties

• Solubility: Solubility (25°C) In vitro DMSO: 100 mg/mL (41.46 mM); Water: 100 mg/mL (41.46 mM); Ethanol: Insoluble