average Mₙ 10,000, PDI ≤1.1 for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C,Argon charged Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 14 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Poly (L-lactide) is a semi-crystalline polymer which exhibits strong optical rotation and good mechanical properties. It is mostly used in the synthesis of degradable polymers which are used in orthopaedic devices, in dental applications, as scaffolds for autografted new skin, wound covers, anastomose systems and stents. They are biodegradable since the polyester backbone degrades by simple hydrolysis to form non-toxic compounds.Drug Delivery including coating nanoparticles; end-group functionalization; macroinitiator or block precursor.
| Canonical Smiles | CC1C(=O)OC(C(=O)O1)C |
|---|---|
| IUPAC Name | 3,6-dimethyl-1,4-dioxane-2,5-dione |
| InChIKey | JJTUDXZGHPGLLC-UHFFFAOYSA-N |
| INCHI | 1S/C6H8O4/c1-3-5(7)10-4(2)6(8)9-3/h3-4H,1-2H3 |
| Isomeric SMILES | CC1C(=O)OC(C(=O)O1)C |
| Alternate CAS | 26161-42-2 |
| Reaxy-Rn | 82121 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=82121&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Class | Dioxanes |
| Subclass | 1,4-dioxanes |
| Intermediate Tree Nodes | Not available |
| Direct Parent | 1,4-dioxanes |
| Alternative Parents | Dicarboxylic acids and derivatives Lactones Carboxylic acid esters Oxacyclic compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds |
| Molecular Framework | Aliphatic heteromonocyclic compounds |
| Substituents | Dicarboxylic acid or derivatives - Para-dioxane - Lactone - Carboxylic acid ester - Oxacycle - Carboxylic acid derivative - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Aliphatic heteromonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as 1,4-dioxanes. These are organic compounds containing 1,4-dioxane, an aliphatic six-member ring with two oxygen atoms in ring positions 1 and 4. |
| External Descriptors | a small molecule |
| Sensitivity | Moisture sensitive；Heat sensitive |
|---|---|
| Melt Point(°C) | 180 °C |
| Molecular Weight | 144.120 g/mol |
| XLogP3 | 0.600 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 0 |
| Exact Mass | 144.042 Da |
| Monoisotopic Mass | 144.042 Da |
| Topological Polar Surface Area | 52.600 Ų |
| Heavy Atom Count | 10 |
| Formal Charge | 0 |
| Complexity | 155.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 2 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Ming Qian, Shun Li, Kun Xi, Jincheng Tang, Xiaofeng Shen, Yong Liu, Ran Guo, Nannan Zhang, Yong Gu, Yun Xu, Wenguo Cui, Liang Chen. (2023) ECM-engineered electrospun fibers with an immune cascade effect for inhibiting tissue fibrosis. Acta Biomaterialia, [PMID:37673231] [10.1016/j.actbio.2023.08.058] |
| 2. Zexin Zhao, Yuan Xu, Pengpeng Zou, Long Xu, Jun Cai. (2023) Developing a pachyman/polyvinyl alcohol-polylactic acid bilayer film as multifunctional packaging and its application in cherry tomato preservation. LWT-FOOD SCIENCE AND TECHNOLOGY, [PMID:] [10.1016/j.lwt.2023.115249] |
| 3. Yang Sun, Qianrong Zhou, Yawei Du, Jian Sun, Wei Bi, Wenjuan Liu, Ruixue Li, Xingwen Wu, Fei Yang, Liang Song, Ni Li, Wenguo Cui, Youcheng Yu. (2022) Dual Biosignal-Functional Injectable Microspheres for Remodeling Osteogenic Microenvironment. Small, 18 (36): (2201656). [PMID:35419952] [10.1002/smll.202201656] |
| 4. Chaojun Fu, Fanrong Ai, Jianzhen Huang, Zhiying Shi, Xiluan Yan, Xiangjuan Zheng. (2022) Eu doped Ti3C2 quantum dots to form a ratiometric fluorescence platform for visual and quantitative point-of-care testing of tetracycline derivatives. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:35168034] [10.1016/j.saa.2022.120956] |
| 5. Xiumei Yan, Yi Yu, Shaobing Wang, Haixing Xu, Qundi He, Jing Wen, Jingyi Xu, Kebi Li, Zhijun Huang, Peihu Xu. (2021) Preparation and characterization of conductive nerve guide conduit filled with dual drug-loaded nanofibers. JOURNAL OF BIOACTIVE AND COMPATIBLE POLYMERS, [PMID:] [10.1177/08839115211053917] |
| 6. Chenyang Cai, Yongqin Wang, Zechang Wei, Yu Fu. (2021) Biomimetic 3D Membranes with MXene Heterostructures for Superior Solar Steam Generation, Water Treatment, and Electricity Generation. Solar RRL, 5 (11): (2100593). [PMID:] [10.1002/solr.202100593] |
| 7. Xu Haixing, Li Rui, Li Yiping, He Qundi, Yan Xiumei, Shu Tao, Yang Haixia, Lü Yifei, Li Zheng, Xu Runtian, Xiong Chengjie, Xu Peihu. (2021) Preparation and Characterization of Poly Lactic Acid/Graphene Oxide/Nerve Growth Factor Scaffold with Electrical Stimulation for Peripheral Nerve Regeneration in vitro. JOURNAL OF WUHAN UNIVERSITY OF TECHNOLOGY-MATERIALS SCIENCE EDITION, 35 (6): (1149-1161). [PMID:] [10.1007/s11595-020-2367-5] |
| 8. Xiaonan Deng, Sihong Ye, Kun Liu, Changfeng Li, Fangzhi Liu, Xiaoming Yan. (2020) Permeability of N, P, K-fertilizer nutrient and water vapor through PLA, PLA/PS, and PLA/HA membranes. Polish Journal of Chemical Technology, 22 (4): (61-68). [PMID:] [10.2478/pjct-2020-0040] |
| 9. Hao Zhang, Yilin Dong, Keke Huang, Jingsheng Liu, Bo Dong, Feng Wang. (2019) Immortal Ring Opening Polymerization of ε-caprolactone and rac-lactide by magnesium precatalysts bearing sterically congested phenoxide ligands. EUROPEAN POLYMER JOURNAL, [PMID:] [10.1016/j.eurpolymj.2019.06.029] |
| 10. Zhefu Li, Binling Chen, Xianfeng Wang, Jun Nie, Guiping Ma. (2019) Electrospun bamboo-like Fe3C encapsulated Fe-Si-N co-doped nanofibers for efficient oxygen reduction. JOURNAL OF COLLOID AND INTERFACE SCIENCE, [PMID:30925431] [10.1016/j.jcis.2019.03.079] |
| 11. Tiantian Song, Weichao Shi. (2024) Polymer crystallization and optical birefringence modulated by solvent evaporation in sessile droplets. POLYMER, [PMID:] [10.1016/j.polymer.2024.127287] |
| 12. Fenglei Chen, Xiaoshuai Peng, Keng Chen, Jiapeng Song, Yue Fan, Peng Wang, Xingxing Shi, Zhaopeng Cai. (2025) Chitosan-based adhesive patch with anti-inflammatory, pro-healing, and immunomodulatory properties for dural defect repair. CARBOHYDRATE POLYMERS, [PMID:40947264] [10.1016/j.carbpol.2025.124189] |
| 13. Lunjie Zhao, Jianyou Xia, Congcong Yang, Jianping Tao, Shanfu Zhang, Wentao Hu, Chen Zhang, Jiuwu Zhang, Qiang Li, Yujie Xu. (2025) Poly (L-lactic acid)/Gelatin microfiber membrane loaded with Mitomycin C promoting bladder defect repair by anti-fibrosis and anti-bacteria. Journal of Materials Chemistry B, [PMID:40237778] [10.1039/D4TB02521K] |
| 14. Ziyi Feng, Meiqi Jin, Minhao Li, Jia Guo, Shu Guo, Huazhe Yang, Xiaoting Sun. (2026) Pomegranate-inspired bionic microgel/periosteum composite harnessing reactive oxygen species for immune-engineered bone regeneration. JOURNAL OF CONTROLLED RELEASE, [PMID:] [10.1016/j.jconrel.2026.114818] |
