Pralnacasan - Moligand™, 10 mM in DMSO , CAS No.192755-52-5

CAS: 192755-52-5 Cat. No.: P1498913 PubChem CID: 153270

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Pralnacasan (VX-740) is a potent, selective, non-peptide and orally active interleukin-1β converting enzyme (ICE, caspase 1 ) inhibitor with a K i of 1.4 nM. Pralnacasan inhibits proinflammatory cytokines IL-18 , IL-1β , and IFN-γ . Pralnacasan has the potential for osteoarthritis and rheumatoid arthritis treatment .

Specifications

Specifications & Purity

Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Names and Identifiers

• Isomeric SMILES: CCO[C@H]1[C@H](CC(=O)O1)NC(=O)[C@@H]2CCCN3N2C(=O)[C@H](CCC3=O)NC(=O)C4=NC=CC5=CC=CC=C54
• Alternate CAS: 192755-52-5
• PubChem CID: 153270
• MeSH Entry Terms: N-((2R,3S)-2-ethoxytetrahydro-5-oxo-3-furanyl)octahydro-9-((1-isoquinolinylcarbonyl)maino)-6,10-dioxo-(1S,9S)-6H-pyridazino(1,2-a)(1,2)diazepine-1-carboxamide;pralnacasan