Pseudoutp, Pseudouridine triphosphate in Chinese, is one of the most commonly used modified nucleoside triphosphates. It can be used in a variety of related applications in molecular biology, such as in vitro transcription, siRNA synthesis and so on. It is found that the mRNA synthesized by pseudouridine triphosphate or N1 methyl pseudouridine triphosphate has better stability and translation efficiency, and reduces the autoimmunity of mRNA, which makes it widely used in the field of disease prevention and treatment. This product is PUTP sodium saline solution with purity ≥ 99% (HPLC), the concentration is 100mm ± 5mm, and there is no pollution of endonuclease, exonuclease and ribonuclease.
This product is produced with medicinal raw and auxiliary materials, and all kinds of pollution in the production process are strictly controlled. It complies with the product production and quality management procedures of GMP, so as to ensure the traceability of the production process and all raw and auxiliary materials.
Follow the following specifications
1. ISO 9001:2015, certified facility。
2. GMP appendix - cell therapy products State Drug Administration.
3. General introduction to human gene therapy - Chinese Pharmacopoeia 2020, national pharmacopoeia commission.
4. USP chapter < 1043 >, ancillary materials for cell, gene, and tissue engineered products are used as excipients in cell therapy, gene therapy and tissue engineering products.
5. USP chapter < 92 >, growth factors and cytokines used in cell therapy manufacturing.
6. Ph. Eur. General chapter 5.2.12, raw materials of biological origin for the production of cell-based and gene therapy medical products.
Storage temperature
The product can be stored or transported at - 20 ± 5 ℃ for a short time, and stored at - 70 ± 5 ℃ for a long time. The product is valid for 1 years;
Avoid multiple freeze-thaw cycles and frequent temperature changes;
The product may form a concentration gradient after freezing. It needs to be fully mixed before use.
K2223053