≥96%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C,Argon charged Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Raptinal, a agent that directly activates caspase-3, initiates intrinsic pathway caspase-dependent apoptosis. Raptinal is able to rapidly induce cancer cell death by directly activating the effector caspase-3, bypassing the activation of initiator caspase-8 and caspase-9.
Application：
Raptinal showed complete cytochrome c release within 30 minutes and caspase-3 activation within one hour of exposure (10 μM). Despite its general cytotoxicity in both cancer and non-cancer cell cultures (Cell death induction EC50 = 0.6-3.4 μM in 24 hr), no hematologic toxicity was observed 7 days following single 60 mg/kg i.v. dosing in mice. Studies show that daily i.p. injection (20 mg/kg) is efficacious in suppressing murine B16-F10 melanoma and 4T1 breast cancer expansion in vivo (by ~60% and 50% in 6 days, respectively).
| Pubchem Sid | 528766931 |
|---|---|
| Canonical Smiles | C1=CC=C2C(=C1)C3=CC=CC=C3C2(C=O)C4(C5=CC=CC=C5C6=CC=CC=C64)C=O |
| IUPAC Name | 9-(9-formylfluoren-9-yl)fluorene-9-carbaldehyde |
| InChIKey | GLANOOJJBKXTMI-UHFFFAOYSA-N |
| INCHI | 1S/C28H18O2/c29-17-27(23-13-5-1-9-19(23)20-10-2-6-14-24(20)27)28(18-30)25-15-7-3-11-21(25)22-12-4-8-16-26(22)28/h1-18H |
| Isomeric SMILES | C1=CC=C2C(=C1)C3=CC=CC=C3C2(C=O)C4(C5=CC=CC=C5C6=CC=CC=C64)C=O |
| PubChem CID | 355994 |
| Molecular Weight | 386.45 |
| Reaxy-Rn | 2303836 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Class | Fluorenes |
| Subclass | Not available |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Fluorenes |
| Alternative Parents | Organic oxides Hydrocarbon derivatives Aldehydes |
| Molecular Framework | Aromatic homopolycyclic compounds |
| Substituents | Fluorene - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Aldehyde - Aromatic homopolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as fluorenes. These are compounds containing a fluorene moiety, which consists of two benzene rings connected through either a cyclopentane, cyclopentene, or cyclopenta-1,3-diene. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 H2529565 | Certificate of Analysis | Jun 25, 2025 | R404974 |
| H2529566 | Certificate of Analysis | Jun 25, 2025 | R404974 |
| H2529567 | Certificate of Analysis | Jun 25, 2025 | R404974 |
| F2415182 | Certificate of Analysis | May 08, 2024 | R404974 |
| F2415183 | Certificate of Analysis | May 08, 2024 | R404974 |
| F2415204 | Certificate of Analysis | May 08, 2024 | R404974 |
| F2415208 | Certificate of Analysis | May 08, 2024 | R404974 |
| F2415217 | Certificate of Analysis | May 08, 2024 | R404974 |
| F2415241 | Certificate of Analysis | May 08, 2024 | R404974 |
| Solubility | DMSO: 18.0 mg/mL (46.6 mM), Sonification and heating to 60℃ are recommended. |
|---|---|
| Sensitivity | Air Sensitive,Heat Sensitive |
| x_melt_point_char | 219 °C |
| Molecular Weight | 386.400 g/mol |
| XLogP3 | 4.900 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 3 |
| Exact Mass | 386.131 Da |
| Monoisotopic Mass | 386.131 Da |
| Topological Polar Surface Area | 34.100 Ų |
| Heavy Atom Count | 30 |
| Formal Charge | 0 |
| Complexity | 580.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
