S186 - ≥99% , CAS No.97759-16-5

CAS: 97759-16-5 Cat. No.: S648733 Molecular Weight: 321.15 PubChem CID: 127255645

GRADE & PURITY ≥99%

Storage

Store at 2-8°C,Desiccated

Shipped In

Wet ice

Overview

S186 is a kind of sodium salts of calcium-acetylpropylamine phosphonate(APA); a new strontium-specific chelating agent.IC50 value:Target:In a case test for 4 person who took 90Sr in due to an internal contaminated accident, the APAP was adminstrated intramuscularly once a day for 3 days, the increase excretion of 90Sr was obvious and no side effects was observed among them. Recently, S186 has also been approved by Shanghai Municipal Health Bureau for emergency medical use in China.

Form:Solid

Specifications

Specifications & Purity

≥99%

Biochemical and Physiological Mechanisms

S186 is a kind of sodium salts of calcium-acetylpropylamine phosphonate(APA); a new strontium-specific chelating agent.\nIC50 value:\nTarget: \nIn a case test for 4 person who took 90Sr in due to an internal contaminated accident, the APAP was adminstrate

Storage

Store at 2-8°C, Desiccated

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥99%

Names and Identifiers

• Canonical Smiles: CCC(NC(=O)C)(P(=O)(O)O)P(=O)(O)O.[Na].[Ca]
• InChIKey: WPTHTLCSASTWJP-UHFFFAOYSA-N
• INCHI: 1S/C5H13NO7P2.Ca.Na/c1-3-5(6-4(2)7,14(8,9)10)15(11,12)13;;/h3H2,1-2H3,(H,6,7)(H2,8,9,10)(H2,11,12,13)
• PubChem CID: 127255645
• Molecular Weight: 321.15

Chemical and Physical Properties

• Solubility: H2O : 25 mg/mL (77.85 mM; Need ultrasonic) DMSO : <1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble or slightly soluble)