Sarakalim , Sulfonylurea receptors; K-ATP channels opener, CAS No.148430-28-8, Sulfonylurea receptors; K-ATP channels opener

CAS: 148430-28-8 Cat. No.: S671076 Molecular Weight: 408.4

Synonyms

Sarakalim | 6-trifluoromethyl-2,2-dimethyl-3-(N-hydroxyacetamido)methyl-4-(2-oxo-1,2-dihydropyridin-1-yl)-2H-1-benzopyran | N-((2,2-Dimethyl-4-(2-oxo-1(2H)-pyridyl)-6-(trifluoromethyl)-2H-1-benzopyran-3-yl)methyl)acetohydroxamic acid | UNII-2BY2U8GO3M | C

Storage

Room temperature

Specifications

Synonyms

Sarakalim | 6-trifluoromethyl-2, 2-dimethyl-3-(N-hydroxyacetamido)methyl-4-(2-oxo-1, 2-dihydropyridin-1-yl)-2H-1-benzopyran | N-((2, 2-Dimethyl-4-(2-oxo-1(2H)-pyridyl)-6-(trifluoromethyl)-2H-1-benzopyran-3-yl)methyl)acetohydroxamic acid | UNII-2BY2U8GO3M | C

Storage

Room temperature

Action Type

OPENER

Mechanism of action

Sulfonylurea receptors; K-ATP channels opener

Product Properties

• ALogP: 1.8

Names and Identifiers

• Canonical Smiles: CC(=O)N(CC1=C(C2=C(C=CC(=C2)C(F)(F)F)OC1(C)C)N3C=CC=CC3=O)O
• IUPAC Name: N-[[2,2-dimethyl-4-(2-oxopyridin-1-yl)-6-(trifluoromethyl)chromen-3-yl]methyl]-N-hydroxyacetamide
• InChIKey: FXRJKZVWFJSKGI-UHFFFAOYSA-N
• INCHI: 1S/C20H19F3N2O4/c1-12(26)25(28)11-15-18(24-9-5-4-6-17(24)27)14-10-13(20(21,22)23)7-8-16(14)29-19(15,2)3/h4-10,28H,11H2,1-3H3
• Isomeric SMILES: CC(=O)N(CC1=C(C2=C(C=CC(=C2)C(F)(F)F)OC1(C)C)N3C=CC=CC3=O)O
• Molecular Weight: 408.4
• Reaxy-Rn: 13761749
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=13761749&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Class Benzopyrans
      • Subclass 1-benzopyrans

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Class: Benzopyrans
• Subclass: 1-benzopyrans
• Intermediate Tree Nodes: Not available
• Direct Parent: 2,2-dimethyl-1-benzopyrans
• Alternative Parents: Pyridinones Alkyl aryl ethers Dihydropyridines Benzenoids Acetamides Acetohydroxamic acids Heteroaromatic compounds Lactams Oxacyclic compounds Azacyclic compounds Organic oxides Organonitrogen compounds Alkyl fluorides Organofluorides Carbonyl compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: 2,2-dimethyl-1-benzopyran - Alkyl aryl ether - Dihydropyridine - Pyridinone - Hydropyridine - Pyridine - Benzenoid - Heteroaromatic compound - Acetohydroxamic acid - Acetamide - Hydroxamic acid - Lactam - Carboxylic acid derivative - Ether - Oxacycle - Azacycle - Organohalogen compound - Alkyl halide - Hydrocarbon derivative - Organic oxide - Alkyl fluoride - Organic oxygen compound - Organic nitrogen compound - Carbonyl group - Organofluoride - Organonitrogen compound - Organooxygen compound - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as 2,2-dimethyl-1-benzopyrans. These are organic compounds containing a 1-benzopyran moiety that carries two methyl groups at the 2-position.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y