Sterculic acid - ≥99% , CAS No.738-87-4

CAS: 738-87-4 Cat. No.: S647714 Molecular Weight: 294.47

GRADE & PURITY ≥99%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

Sterculic acid is a stearoyl-CoA desaturase-1 ( SCD1 ) inhibitor. Sterculic acid specifically inhibits the delta-9 desaturase ( Δ9D ) activity with an IC 50 value of 0.9 μM

In Vitro

Sterculic acid (SA) is a cyclopropene fatty acid originally found in the seeds of the plant Sterculia foetida with numerous biological activities . Sterculic acid is able to reduce adrenomedullin expression (AP, RP, APS, IML, in preparation) . Sterculic acid is also able to mediate anti-inflammatory and protective effects . Sterculic acid has a potent luteolytic effect in ovines by inhibition in the synthesis of progesterone, which causes luteal regression . MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Sterculic acid has been proposed as a potential tool for the treatment of metabolic syndrome (MS) since it inhibits the activity of the stearoyl-CoA desaturase-1 (SCD1)\nin vivo . MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Liquid

IC50& Target:delta-9 desaturase 0.9 μM (IC 50 )

Specifications

Specifications & Purity

≥99%

Biochemical and Physiological Mechanisms

Sterculic acid is a stearoyl-CoA desaturase-1 ( SCD1 ) inhibitor. Sterculic acid specifically inhibits the delta-9 desaturase ( Δ9D ) activity with an IC 50 value of 0.9 μM.

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥99%

Names and Identifiers

• Canonical Smiles: CCCCCCCCC1=C(C1)CCCCCCCC(O)=O
• Molecular Weight: 294.47