Strontium solution - analytical standard, 0.80 mg/L,in 1%HCl , CAS No.7440-24-6

CAS: 7440-24-6 Cat. No.: S140765 Formula: Sr Molecular Weight: 87.62 EC Number: 231-133-4 PubChem CID: 5359327

GRADE & PURITY Analytical standard, 0.80 mg/L,in 1%HCl

Storage

Room temperature

Shipped In

FedEx DG Service

Specifications

Specifications & Purity

analytical standard, 0.80 mg/L,in 1%HCl

Storage

Room temperature

Shipped In

FedEx DG Service

Grade

Analytical standard

Names and Identifiers

Isomeric SMILES

[Sr]

WGK Germany

3

Alternate CAS

10476-85-4

PubChem CID

5359327

UN Number

3208

Molecular Weight

87.62

Chemical and Physical Properties

• x_boil_point_char: 1384°C
• x_melt_point_char: 769°C

Application Protocols

The following are general, literature-based protocols for using a single-element strontium standard in elemental analysis. They are not item-specific; consult the CoA/Spec Sheet and your laboratory SOPs.

A. ICP-MS calibration (general)

• Stock verification: Confirm stock concentration and matrix from CoA (Not specified for this item).
• Prepare diluent: Type I water + 1–2% v/v HNO3.
• Prepare calibration points: e.g., 0, 0.5, 1, 5, 10, 50 µg/L Sr by serial dilution using gravimetry. Include an independent check standard from a second source.
• Internal standard: Add an internal standard (e.g., Y at 5–10 µg/L) to all standards/samples if per SOP.
• Acquire data: Measure isotopes 86, 87, 88 with appropriate collision/reaction cell settings; apply blank subtraction and linear regression with weighting if needed.

B. ICP-OES calibration (general)

• Select lines with minimal interference (e.g., near 407.771 nm or 421.552 nm; confirm on your instrument). Prepare µg/L–mg/L range standards per method.
• Match matrix and viscosity between standards and samples to control nebulization efficiency.

C. AAS (flame) calibration (general)

• Prepare mg/L range Sr standards in dilute HNO3. Add ionization buffer if required by method.

Notes: Use low-contamination technique, pre-rinse containers, and verify linearity and recovery with CCVs. Item-specific concentration/matrix are Not specified for this item.

Biological Roles

Biological context (literature/general; not specific to this item):

• Strontium (Sr) is an alkaline-earth element chemically similar to calcium. In biological systems, Sr2+ can substitute for Ca2+ in some processes due to comparable ionic radius and charge, though with altered kinetics/affinities.
• Membrane transport: Sr2+ can permeate certain voltage-gated calcium channels and is used experimentally as a Ca2+ surrogate to probe exocytosis and synaptic transmission because it supports asynchronous neurotransmitter release more strongly than Ca2+ under some conditions.
• Binding and signaling: Sr2+ interacts with Ca2+-binding proteins (e.g., EF-hand motifs) with different affinities, enabling mechanistic studies of calcium-dependent processes.
• Mineral incorporation: In mineralized tissues and biominerals, Sr can substitute into calcium phosphate or carbonate lattices. Sr/Ca ratios in shells, corals, and bones are used as proxies in paleoceanography and environmental tracing.
• Toxicology: Soluble Sr salts are of relatively low acute toxicity, but chronic exposure at high levels may disrupt calcium homeostasis. Radioisotopes (e.g., 90Sr) are radiotoxic; however, radioisotopes are not relevant to this product unless explicitly stated (none specified for this item).

Application note: This analytical standard is intended for research and analytical calibration only. It is not formulated for biological assays or clinical use. Item-specific composition details (matrix, concentration) are Not specified for this item; consult the CoA before introducing into biological systems for spike-recovery studies.

Buffer Applications

This product is not a buffering reagent. Strontium analytical standards are not typically used to prepare buffer systems.

If spike-recovery or matrix studies in biological buffers are required (literature/general):

• Maintain low concentrations of phosphate, sulfate, and carbonate when introducing Sr2+ into buffers, as these anions can precipitate Sr salts (e.g., Sr3(PO4)2, SrSO4, SrCO3).
• Consider using MES, HEPES, or acetate buffers at modest ionic strength and pH 5.5–7.4 to minimize precipitation, and chelators (EDTA/EGTA) must be avoided unless complexation is intended.

Item-specific buffer compatibility, concentration, and matrix are Not specified for this item; refer to CoA/Spec Sheet and validate experimentally.

Green Alternatives

Context: Single-element standards are necessary for quantitative elemental analysis, but choices in matrix, concentration range, and workflow can reduce waste and environmental impact.

Greener practice options (literature/general):

• Use multi-element mixed standards when appropriate to minimize the number of stock bottles and shipping events while maintaining analytical needs.
• Right-size calibration ranges to the sample concentration window to reduce the number and volume of calibration points, minimizing acid and plastic waste.
• Choose nitrate matrices over chloride when possible to reduce formation of chlorinated byproducts during waste treatment and to avoid Cl-based interferences; confirm compatibility with your methods.
• Employ on-demand dilution systems or gravimetric dilution in reusable PFA vessels to cut single-use plastics.
• Implement closed-loop waste collection and neutralization procedures, segregating acidic metal-containing waste for recycling or appropriate disposal.

Comparison (literature/general; illustrative only):

• Single-element Sr standard vs. multi-element calibration blend
  • Pros (single-element): maximal flexibility in concentration tuning; reduced inter-element interactions; ideal for interference studies.
  • Pros (multi-element): fewer containers, lower storage footprint, reduced solvent and packaging waste; efficient for routine multi-analyte methods.
  • Tradeoffs: Multi-element blends may have reduced stability windows or interaction constraints; verify with CoA.

Note: Item-specific matrix, concentration, and stabilizers are Not specified for this item; select green alternatives consistent with your method and instrument.

Pharmaceutical Uses

No direct pharmaceutical or excipient use is claimed for this product. It is supplied as an analytical standard for research and laboratory calibration only.

Relevant context (literature/general; not specific to this item):

• Strontium salts have historical and regulatory contexts in certain healthcare settings; however, such uses are outside the scope of this analytical standard and must not be inferred.
• In pharmaceutical quality control, strontium standards may be used to calibrate elemental analysis techniques (e.g., ICP-MS per ICH Q3D elemental impurities guidance) when assessing Sr as an impurity or as part of method validation for related alkaline-earth elements.

Practical notes:

• When used in GMP/GLP environments, ensure that the calibration standard’s traceability, uncertainty, and storage conditions are documented. Item-specific details such as concentration, matrix, and metrological traceability are Not specified for this item; consult the CoA/Spec Sheet.
• Avoid cross-contamination: dedicate plasticware to elemental standards, and verify cleanliness by running reagent blanks.

Regulatory reminder: For research use only. Not for human or veterinary diagnostic, therapeutic, or clinical applications.

Physical Properties

Item-specific physical properties for this solution (e.g., exact concentration, density, matrix acid and normality, pH, appearance) are Not specified for this item; refer to CoA/Spec Sheet.

Literature/general properties (for context only; not item specifications):

• Elemental strontium (metal)
  • Melting point: ~777 °C (literature)
  • Boiling point: ~1382 °C (literature)
  • Density (20–25 °C): ~2.64 g/cm3 (literature)
  • Appearance: soft, silvery metal that rapidly tarnishes in air (literature)
• Aqueous Sr2+ solutions (typical analytical standards)
  • Appearance: colorless, clear solutions when prepared in high-purity water with mineral acid (literature)
  • Solubility: Sr2+ salts such as Sr(NO3)2 and SrCl2 are highly water-soluble; SrCO3 and SrSO4 are sparingly soluble (literature)
  • Hydrolysis: Minimal in acidic media; precipitation of carbonates/hydroxides occurs in basic media or in contact with carbonate sources (literature)
  • LogP: Not applicable to inorganic ions
  • Refractive index: Matrix-dependent (commonly near that of water for dilute standards)

Instrumental context (literature/general):

• Sr has strong emission/absorption lines used in AAS/ICP-OES; prominent ICP-MS isotope masses include 84, 86, 87, 88 (88Sr is most abundant) with potential isobaric interferences (e.g., 88Kr in some plasmas; literature). These details guide choice of analytical lines/masses but do not define the item’s specifications.

Quality and Grades

• Item grade: Analytical standard (as provided). This designation indicates the product is intended for quantitative analytical chemistry (e.g., ICP-OES, ICP-MS, AAS, titrimetry), emphasizing composition accuracy, stability, and low background impurities.

• What “Analytical standard” typically implies (literature/general):

  • Concentration accuracy and homogeneity suitable for calibration and quality control, often accompanied by a Certificate of Analysis reporting the stated concentration, uncertainty, matrix composition, and lot-specific impurity profile.
  • Low trace-metal contaminants to minimize spectral interferences and background signals in trace analysis.
  • Stabilized matrix (commonly dilute mineral acid) to prevent adsorption or precipitation of the analyte ion over shelf life.

• This item’s specifics: concentration, matrix acid, traceability (e.g., to national metrology institutes), expanded uncertainty, and stabilizers are Not specified for this item; refer to CoA/Spec Sheet.

• Practical implications:

  • Use high-purity plasticware (PP, PFA) to avoid leaching or adsorption when working at µg/L to mg/L levels.
  • Implement bracketing standards and independent check standards to verify instrument linearity and recovery.
  • Record lot number and expiration date from the CoA to maintain traceability in regulated workflows.

• UV/Vis suitability: For ICP/AAS calibration, UV cutoff is irrelevant. For any spectrophotometric application, baseline absorbance will be dominated by the matrix acid/water; item-specific UV data are Not specified for this item.

Reaction and Applications

As an analytical standard, this product is primarily intended for calibration and quality control rather than for use as a reagent in synthetic transformations.

Analytical applications (literature/general):

• ICP-MS/ICP-OES calibration: Prepare multi-point calibration curves for Sr over the required analytical range. Monitor isotopes 84/86/87/88 (88Sr most abundant) and apply interference corrections as validated. Internal standards (e.g., Y, In, Rh) may be employed to correct drift, though selection depends on method design.
• AAS/Flame emission: Use for instrument calibration and performance checks. Add ionization buffers (e.g., KCl/CsCl) in flame AAS if required by method to control ionization equilibria in the flame.
• Isotope dilution (advanced): With appropriate enriched isotopes (not part of this item), Sr can be quantified by isotope dilution ICP-MS. This stock could serve for spike/recovery checks (method dependent).

Non-analytical chemistry: While Sr2+ has roles in materials synthesis (e.g., precursors for Sr-containing ceramics or perovskites), analytical-standard solutions are not typically used for such reactions due to unknown or unsuitable counterions and low cost-effectiveness. If used exploratorily, avoid conditions that precipitate SrCO3 or SrSO4; maintain slight acidity and exclude sulfate/carbonate sources.

Item-specific application notes: Manufacturer-provided “Manufacturer Applications” are not specified for this item. Use cases should follow validated SOPs for your instrument and regulatory environment.

Reaction Conditions

For this analytical standard, “reaction conditions” are best interpreted as preparation and use conditions for calibration solutions rather than chemical transformations.

General preparation/use (literature/general; verify against your SOP and CoA):

• Working range: Prepare calibrators spanning the expected Sr concentration in samples (e.g., ICP-MS: low ng/L to µg/L; ICP-OES: µg/L to mg/L). Use C1V1 = C2V2 with gravimetric dilutions preferred for accuracy.
• Matrix: Use high-purity Type I water acidified to ~1–2% v/v HNO3 (or match the matrix of the stock if specified in the CoA). Avoid sulfate, phosphate, and carbonate in diluents to prevent precipitation.
• Containers: Pre-rinse plasticware (PP/HDPE/PFA) with matrix acid and validate blanks. Avoid glass at trace levels unless shown not to bias Sr.
• Equilibration: Allow solutions to reach room temperature; mix by inversion. For ICP-MS, allow a short stabilization period to minimize memory.
• Instrumental notes: For ICP-MS, common isotopes are 86, 87, 88; check for Kr or Rb interferences depending on plasma/argon supply and collision/reaction cell conditions. For ICP-OES, select robust lines with minimal spectral overlap and matrix effects.
• Quality checks: Include a second-source check standard, continuing calibration verification (CCV), and method blanks every 10–20 samples. Monitor recovery within acceptance limits defined by your method.

Item-specific parameters (stock concentration, matrix acid, stabilizers) are Not specified for this item; refer to CoA/Spec Sheet.

Safety and Handling

Item-specific hazard classification, pictograms, and H-statements are Not specified for this item; refer to SDS and CoA/Spec Sheet for authoritative information.

General guidance for strontium analytical standards (literature/general):

• Likely matrix: Many single-element standards are supplied in dilute mineral acid (e.g., HNO3 or HCl) to stabilize Sr2+. If acidic, the solution can be corrosive to skin/eyes and reactive with bases and carbonates. For this item, matrix and acid normality are Not specified—verify before use.
• Primary hazards: Corrosivity (if acidic), general toxicity from ingestion. Soluble Sr2+ can mimic Ca2+ biologically; avoid ingestion and inhalation of aerosols. Not flammable as an aqueous solution.
• PPE: Wear lab coat, chemical-resistant gloves (e.g., nitrile), splash goggles. Work in a fume hood when preparing dilutions or nebulized aerosols for spectroscopy.
• Incompatibilities: Avoid contact with strong bases (may cause precipitation and heat), carbonates/bicarbonates (precipitation of SrCO3), and sulfates (SrSO4 precipitation). Keep away from reactive metals if the matrix is acidic.
• First aid (overview; defer to SDS): Rinse skin/eyes with water for ≥15 minutes after contact; remove contaminated clothing. If inhaled, move to fresh air. If ingested, rinse mouth—do not induce vomiting; seek medical attention.
• Spill response: Contain, neutralize acids if present (after confirming matrix), absorb with inert material, and dispose per local regulations.
• Peroxides: Not applicable. Oxidizing properties depend on matrix acid; nitric acid matrices are oxidizing—use appropriate precautions.

Solvent Selection

This product is supplied as a solution; the diluent/matrix is Not specified for this item. In analytical use, solvent selection focuses on compatibility with the instrument and prevention of precipitation/adsorption.

General guidance (literature/general):

• Typical diluents: 1–2% (v/v) high-purity nitric acid in Type I water (ASTM) is commonly used for Sr2+ standards to enhance stability and reduce memory effects in ICP-MS/OES. Hydrochloric acid is also used in some methods; choose based on method validation and interference control. Always match the matrix of calibration standards to that of samples where possible.
• Miscibility: Aqueous inorganic standards are fully miscible with water and water–acid mixtures; avoid alcohols/organic solvents that may change nebulization characteristics or cause salt precipitation without method validation.
• Container compatibility: Use metal-free plastic (PP, HDPE, or PFA) for storage/dilution. Glass can adsorb/introduce alkali/alkaline-earth species at low concentrations—use only if validated.
• Rinse solutions: For ICP-MS, matrix-matched acid rinses help mitigate memory. For AAS flame, water/acid diluents are adequate; avoid phosphate or sulfate in diluents to prevent Sr salt precipitation.

Selection pointers:

• Choose HNO3 matrices for minimal chloride-related interferences and to maintain oxidizing conditions; choose HCl matrices when method-specified or to stabilize certain anions. Confirm with your CoA which matrix the stock solution contains before preparing working ranges.

Storage and Reconstitution

• Storage conditions (item-specific): Room temperature (as provided). Avoid temperature extremes and direct sunlight. Keep container tightly closed to minimize contamination and evaporation.
• Shipping: Shipped via FedEx DG Service (as provided).
• Reconstitution: Not typically applicable—analytical standards are supplied ready-to-use as stock solutions. If preparing working standards, dilute with high-purity Type I water and appropriate acid according to your method and the CoA.
• Container/materials: Store in original, tightly sealed container. When aliquoting, use clean, metal-free plasticware (PP/HDPE/PFA). Avoid glass for ultra-trace work unless validated.
• Stability: Shelf life, concentration, and matrix-specific stability are Not specified for this item; refer to CoA/Spec Sheet. In general (literature/general), keep solutions mildly acidic to prevent precipitation and adsorption.
• Freeze–thaw: Do not freeze unless specified by the manufacturer; freezing can cause concentration changes due to ice segregation. Room-temperature storage is indicated for this item.
• Contamination control: Work under a clean hood where feasible. Rinse pipette tips and vessels with matrix prior to use. Track lot numbers and opening dates; consider storing secondary working stocks to minimize repeated opening of the primary container.
• Disposal: Collect acidic, metal-containing waste separately and dispose of according to institutional and local regulations.

Research Use Note: For research use only.

Structure and Identity

Brief overview: This product is an analytical standard of strontium provided as a solution; concentration and matrix are not specified for this item and should be confirmed from the CoA/Spec Sheet.

• Item-specific identifiers

  • Product name: Strontium solution (Analytical standard)
  • SKU: S140765
  • CAS: 7440-24-6 (assigned to elemental strontium)
  • PubChem CID: 5359327 (strontium)
  • InChIKey: Not specified for this item; refer to CoA/Spec Sheet.
  • SMILES: Not specified for this item; refer to CoA/Spec Sheet.

• Structural features (literature/general)

  • Element: Strontium (Sr), atomic number 38, group 2 alkaline-earth metal.
  • Common oxidation state in solution: +2 (Sr2+). Aqueous strontium exists as a solvated divalent cation with inner-sphere hydration (commonly [Sr(H2O)8]2+ in water, literature).
  • Coordination chemistry: Prefers hard-donor ligands (O-donors). Typical coordination numbers 6–9 depending on ligand set and solvent (literature).

• Molecular formula and mass (literature/general)

  • Molecular formula (elemental): Sr
  • Atomic weight (IUPAC 2021 conventional value): ~87.62 g/mol (literature)

• 2D description in words (literature/general)

  • As an element: a single Sr atom (metal). In aqueous analytical standards, the relevant species is the mononuclear Sr2+ cation, presented as a free ion or as a weakly complexed aqua ion balanced by counteranions from the matrix acid (commonly nitrate or chloride in many standards; specific matrix Not specified for this item; refer to CoA/Spec Sheet).

Synthetic Utility

This product, as an analytical standard solution of Sr, is not typically employed as a synthetic reagent. Its primary role is calibration of analytical instrumentation.

General synthetic context for strontium (literature/general):

• Strontium salts (not analytical standards) participate in materials syntheses (e.g., precursors to perovskites SrTiO3, ferrites, and phosphors). These processes usually require defined counterions (acetate, nitrate, alkoxide) and controlled stoichiometry incompatible with the unknown matrix of an analytical standard.
• Organostrontium reagents (e.g., generated by halogen–metal exchange with strontium metal) are used in advanced organic synthesis for selective additions and cross-couplings, but they are air- and moisture-sensitive and unrelated to aqueous Sr2+ standards.
• As a Lewis acid, Sr2+ can influence ionic equilibria in solution; however, precipitation with common anions (CO3 2−, SO4 2−, PO4 3−) limits its utility in neutral/alkaline media.

Takeaway: If your goal is chemical synthesis or materials preparation, use the appropriate strontium salt or organometallic reagent with known counterions and purity. Reserve this analytical standard for metrology tasks (calibration checks, spike-recovery assessments, instrument qualification). Item-specific composition is Not specified for this item and must be confirmed via CoA/Spec Sheet if any off-label use is contemplated.

Target Specificity

Not applicable. This product is a chemical analytical standard and not a biological affinity reagent. No antigen/epitope specificity, clone, isotype, or species reactivity applies.