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Teniposide - Moligand™, 10mM in DMSO , DNA topoisomerase II inhibitor, CAS No.29767-20-2, DNA topoisomerase II inhibitor

Teniposide - Moligand™, 10mM in DMSO , DNA topoisomerase II inhibitor, CAS No.29767-20-2, DNA topoisomerase II inhibitor

Name: Teniposide - Moligand™, 10mM in DMSO , DNA topoisomerase II inhibitor, CAS No.29767-20-2, DNA topoisomerase II inhibitor
Brand: Aladdin Scientific
SKU: T408960
Availability: InStock

CAS: 29767-20-2 Cat. No.: T408960 Molecular Weight: 656.65 EC Number: 249-831-2 PubChem CID: 452548

2 Citations COA

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Teniposide - Moligand™, 10mM in DMSO CAS No(29767-20-2) by Aladdin Scientific

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AVAILABLE TO ORDER

GRADE & PURITY Moligand™ ? 10mM in DMSO

Synonyms

NSC 122819, VM-26 | (5R,5aR,8aR,9S)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-9-[[4,6-O-[(R)-2-thienylmethylene]-β-D-glucopyranosyl]oxy]-furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview Specifications Product Properties Names and Identifiers Documentation Advanced Data Associated Targets(Human) Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Citations of This Product References Solution Calculators Reviews

🧪

Why this grade

Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 2 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Information

Teniposide (NSC 122819, VM-26) is a chemotherapeutic medication mainly used in the treatment of childhood acute lymphocytic leukemia (ALL).
In vitro

In vivo

Cell Data

cell lines：Fischer rat thyroid (FRT) cells

Concentrations：

Incubation Time：

Powder Purity:≥95%

Specifications

Synonyms

NSC 122819, VM-26 | (5R, 5aR, 8aR, 9S)-5, 8, 8a, 9-tetrahydro-5-(4-hydroxy-3, 5-dimethoxyphenyl)-9-[[4, 6-O-[(R)-2-thienylmethylene]-β-D-glucopyranosyl]oxy]-furo[3', 4':6, 7]naphtho[2, 3-d]-1, 3-dioxol-6(5aH)-one

Specifications & Purity

Moligand™, 10mM in DMSO

Biochemical and Physiological Mechanisms

Teniposide (NSC 122819, VM-26) is a chemotherapeutic medication mainly used in the treatment of childhood acute lymphocytic leukemia (ALL).

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Action Type

INHIBITOR

Mechanism of action

DNA topoisomerase II inhibitor

Product Properties

ALogP	1.2

Names and Identifiers

Isomeric SMILES	COC1=CC(=CC(=C1O)OC)[C@H]2[C@@H]3[C@H](COC3=O)[C@@H](C4=CC5=C(C=C24)OCO5)O[C@H]6[C@@H]([C@H]([C@H]7[C@H](O6)CO[C@H](O7)C8=CC=CS8)O)O
PubChem CID	452548
Molecular Weight	656.65

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Associated Targets(Human)

TOP2A Tclin DNA topoisomerase 2-alpha (0 Activities)

Discover Target: TOP2A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

Solubility	Solubility (25°C) In vitro DMSO: 47 mg/mL (201.11 mM); Water: Insoluble; Ethanol: Insoluble;
Specific Rotation[α]	-111° (C=1,CHCl3:MeOH=9:1)
Melt Point(°C)	247 °C(dec.)

Citations of This Product

How to Cite Aladdin Scientific Products? Citations Search

References

1. Yifan Wu, Xiaoxia Gong, Jianzhong Shen, Kui Zhu. (2023) Postantibiotic leukocyte enhancement-mediated reduction of intracellular bacteria by macrophages. Journal of Advanced Research, [PMID:37290606] [10.1016/j.jare.2023.05.010]
2. Chunsheng Wu, Xiangting Yi, Renzhi Xu, Maokuan Zhang, Yan Xu, Yan Ma, Li Gao, Zhengbao Zha. (2020) Biodistribution of etoposide via intratumoral chemotherapy with etoposide-loaded implants. DRUG DELIVERY, [PMID:32611260] [10.1080/10717544.2020.1787558]

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Reviews

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