TH-257 - 10mM in DMSO , CAS No.2244678-29-1

CAS: 2244678-29-1 Cat. No.: T408969 Molecular Weight: 422.54 PubChem CID: 137796294

GRADE & PURITY 10mM in DMSO

Synonyms

Benzamide, N-​butyl-​4-​[(phenylamino)​sulfonyl]​-​N-​(phenylmethyl)​-

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Information

TH-257 TH-257 is a potent and exquisitely selective LIM kinase (LIMK) inhibitor with IC50 of 84 nM and 39 nM for LIMK1 and LIMK2, respectively.
In vitro

In vivo

Cell Data

cell lines：Human MM cells (HMCLs), peripheral blood lymphocytes (PBLs), bone marrow stromal cells (BMSCs)

Concentrations：

Incubation Time：

Powder Purity:≥98%

Specifications

Synonyms

Benzamide, N-​butyl-​4-​[(phenylamino)​sulfonyl]​-​N-​(phenylmethyl)​-

Specifications & Purity

10mM in DMSO

Biochemical and Physiological Mechanisms

TH-257 is a potent and exquisitely selective LIM kinase (LIMK) inhibitor with IC50 of 84 nM and 39 nM for LIMK1 and LIMK2, respectively.

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

• Isomeric SMILES: CCCCN(CC1=CC=CC=C1)C(=O)C2=CC=C(C=C2)S(=O)(=O)NC3=CC=CC=C3
• PubChem CID: 137796294
• Molecular Weight: 422.54