UNC-2170 - ≥98% , CAS No.1648707-58-7

CAS: 1648707-58-7 Cat. No.: U1426798 Formula: C₁₈H₂₅BrN₂O₅ Molecular Weight: 429.3 PubChem CID: 91885494

GRADE & PURITY ≥98%

Storage

Store at 2-8°C,Protected from light

Shipped In

Wet ice

Overview

UNC-2170 is a functionally active, fragment-like ligand for 53BP1 ( IC 50 =29 µM; K d =22 µM). UNC-2170 shows at least 17-fold selectivity for 53BP1 as compared to nine other methyl-lysine (Kme) reader proteins. 53BP1 is a Kme binding protein that plays a central role in DNA Damage Repair (DDR) pathways and is recruited to sites of double-strand breaks (DSB).

Specifications

Specifications & Purity

≥98%

Storage

Store at 2-8°C,Protected from light

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥98%

Names and Identifiers

• Canonical Smiles: CC(C)(C)NCCCNC(=O)C1=CC(=CC=C1)Br.C(=CC(=O)O)C(=O)O
• IUPAC Name: 3-bromo-N-[3-(tert-butylamino)propyl]benzamide;(Z)-but-2-enedioic acid
• InChIKey: WCAATDGMINWXPJ-BTJKTKAUSA-N
• INCHI: 1S/C14H21BrN2O.C4H4O4/c1-14(2,3)17-9-5-8-16-13(18)11-6-4-7-12(15)10-11;5-3(6)1-2-4(7)8/h4,6-7,10,17H,5,8-9H2,1-3H3,(H,16,18);1-2H,(H,5,6)(H,7,8)/b;2-1-
• Isomeric SMILES: CC(C)(C)NCCCNC(=O)C1=CC(=CC=C1)Br.C(=C\C(=O)O)\C(=O)O
• PubChem CID: 91885494
• Molecular Weight: 429.3