Xanthophyll - ≥75% , CAS No.127-40-2

CAS: 127-40-2 Cat. No.: X109575 Molecular Weight: 568.87 Beilstein Registry Number: 2068547 EC Number: 204-840-0 PubChem CID: 5281243
AVAILABLE TO ORDER
GRADE & PURITY ≥75%
Synonyms
FloraGLO Lutein | INS NO.161B(I) | Oro Glo 7 | SMP1_000317 | (3R,3'R,6R)-4,5-didehydro-5,6-dihydro-beta,beta-carotene-3,3'-diol | Leutein | Lutein - 20% | LUTEIN (MART.) | (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL | AS-63011 | DTX
Storage
Protected from light,Store at -20°C,Argon charged
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
500mg
X109575-500mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$9.90
1g
X109575-1g
1

$9.90

$11.90
Save $2.00 (16.81%)
5g
X109575-5g
2
$22.90
25g
X109575-25g
4
$59.90
100g
X109575-100g
1
$235.90
Enter a quantity for the sizes you want to add.
🧪

Why this grade

≥75% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Protected from light,Store at -20°C,Argon charged Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 35 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
FloraGLO Lutein | INS NO.161B(I) | Oro Glo 7 | SMP1_000317 | (3R, 3'R, 6R)-4, 5-didehydro-5, 6-dihydro-beta, beta-carotene-3, 3'-diol | Leutein | Lutein - 20% | LUTEIN (MART.) | (3R, 3'R, 6S)-4, 5-DIDEHYDRO-5, 6-DIHYDRO-BETA, BETA-CAROTENE-3, 3'-DIOL | AS-63011 | DTX
Specifications & Purity
≥75%
Storage
Protected from light, Store at -20°C, Argon charged
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Purity
≥75%
Names and Identifiers
Pubchem Sid504763342
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504763342
Canonical SmilesCC1=C(C(CC(C1)O)(C)C)C=CC(=CC=CC(=CC=CC=C(C)C=CC=C(C)C=CC2C(=CC(CC2(C)C)O)C)C)C
IUPAC Name(1R)-4-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1R,4R)-4-hydroxy-2,6,6-trimethylcyclohex-2-en-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-3,5,5-trimethylcyclohex-3-en-1-ol
InChIKeyKBPHJBAIARWVSC-RGZFRNHPSA-N
INCHI1S/C40H56O2/c1-29(17-13-19-31(3)21-23-37-33(5)25-35(41)27-39(37,7)8)15-11-12-16-30(2)18-14-20-32(4)22-24-38-34(6)26-36(42)28-40(38,9)10/h11-25,35-37,41-42H,26-28H2,1-10H3/b12-11+,17-13+,18-14+,23-21+,24-22+,29-15+,30-16+,31-19+,32-20+/t35-,36+,37-/m0/s1
Isomeric SMILES CC1=C(C(C[C@@H](C1)O)(C)C)/C=C/C(=C/C=C/C(=C/C=C/C=C(\C)/C=C/C=C(\C)/C=C/[C@H]2C(=C[C@@H](CC2(C)C)O)C)/C)/C
WGK Germany 3
PubChem CID 5281243
Molecular Weight 568.87
Beilstein 2068547

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassLipids and lipid-like molecules
ClassPrenol lipids
SubclassTetraterpenoids
Intermediate Tree Nodes Carotenoids
Direct ParentXanthophylls
Alternative Parents Secondary alcohols  Hydrocarbon derivatives  
Molecular FrameworkAliphatic homomonocyclic compounds
Substituents Xanthophyll - Secondary alcohol - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Alcohol - Aliphatic homomonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as xanthophylls. These are carotenoids containing an oxygenated carotene backbone. Carotenes are characterized by the presence of two end-groups (mostly cyclohexene rings, but also cyclopentene rings or acyclic groups) linked by a long branched alkyl chain. Carotenes belonging form a subgroup of the carotenoids family. Xanthophylls arise by oxygenation of the carotene backbone.
External Descriptors C40 isoprenoids (tetraterpenes)
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Prunus domestica (6 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Capsicum (9 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rubus (6 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Anethum graveolens (3 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rumex acetosa (57 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

11 results found

Lot NumberCertificate TypeDateItem
I2213174Certificate of AnalysisJun 15, 2026 X109575
I2213175Certificate of AnalysisJun 15, 2026 X109575
F1820124Certificate of AnalysisJan 27, 2026 X109575
B2604110Certificate of AnalysisJul 31, 2025 X109575
G2511078Certificate of AnalysisJul 31, 2025 X109575
D1707135Certificate of AnalysisDec 20, 2024 X109575
A2408040Certificate of AnalysisAug 29, 2022 X109575
B2510072Certificate of AnalysisAug 29, 2022 X109575
G2416033Certificate of AnalysisAug 29, 2022 X109575
I2213173Certificate of AnalysisAug 29, 2022 X109575
F1820123Certificate of AnalysisApr 27, 2022 X109575

Show more ⌵

Chemical and Physical Properties
SensitivityLight sensitive
Molecular Weight568.900 g/mol
XLogP311.000
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count10
Exact Mass568.428 Da
Monoisotopic Mass568.428 Da
Topological Polar Surface Area40.500 Ų
Heavy Atom Count42
Formal Charge0
Complexity1270.000
Isotope Atom Count0
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count9
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds9
Covalently-Bonded Unit Count1
Documents & Articles
Citations of This Product
References
1. Gul Muhammad, Parisa Jahanbakhsh-Bonab, Wenlong Xiong, Yongkun Lv, Shen Zhang, Anqi Zhao, Jaber Jahanbin Sardroodi, Jingliang Xu, Md Asraful Alam.  (2023)  Mechanism of deep eutectic solvent-mediated microalgal biomass disintegration for enhanced lutein extraction.  INDUSTRIAL CROPS AND PRODUCTS,      [PMID:] [10.1016/j.indcrop.2023.117940]
2. Islam Md Monirul, Hassan Mahmood Ul, Ishfaq Muhammad, Ripa Farhana Alam, Nadeem Faisal, Ahmad Zeeshan, Xu Jiuliang, Ning Peng, Li Xuexian.  (2023)  Foliar Glutamine Application Improves Grain Yield and Nutritional Quality of Field-Grown Maize (Zea mays L.) Hybrid ZD958.  JOURNAL OF PLANT GROWTH REGULATION,      [PMID:] [10.1007/s00344-023-11121-w]
3. Gaoshuai Zhang, Meijing Zhang, Yiqiao Pei, Kun Qian, Jiao Xie, Qun Huang, Suwen Liu, Na Xue, Yujiao Zu, Hao Wang.  (2023)  Enhancing stability of liposomes using high molecular weight chitosan to promote antioxidative stress effects and lipid-lowering activity of encapsulated lutein in vivo and in vitro.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:37714230] [10.1016/j.ijbiomac.2023.126564]
4. Zhenxia Shi, Gaoyuan Kong, Fangfang Wang, Hui Gao, Anran Wei, Sizhu Ren, Xunyou Yan.  (2023)  Improvement in the stability and bioavailability of pumpkin lutein using β-cyclodextrin microcapsules.  Food Science & Nutrition,  11  (6): (3067-3074).  [PMID:37324919] [10.1002/fsn3.3288]
5. Zhiyu Liu, Songyi Lin, Wenwen Liu, Yoshimasa Nakamura, Yue Tang.  (2022)  Construction of benzyl isothiocyanate-loaded fish skin gelatin-luteolin compound emulsion delivery system, and its digestion and absorption characteristics.  JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE,  103  (4): (1864-1873).  [PMID:36571447] [10.1002/jsfa.12411]
6. Zhi-Ang Liu, Ya-Nan Zuo, Yinghui Xia, Jing Sun, Shuyun Zhu.  (2022)  Enhanced detection of ascorbic acid with cascaded fluorescence recovery of a dual-nanoquencher system.  Analytical Methods,  14  (37): (3632-3637).  [PMID:36052693] [10.1039/D2AY01019D]
7. Fenghui Pan, Wenxia Cui, Lei Gao, Xiaoting Shi, Haiyan Yang, Yun Hu, Man Li.  (2022)  Serum lutein is a promising biomarker for type 2 diabetes mellitus and diabetic kidney disease in the elderly.  JOURNAL OF CLINICAL LABORATORY ANALYSIS,  36  (4): (e24350).  [PMID:35293029] [10.1002/jcla.24350]
8. Li-Hua Pan, Cui-Ling Wu, Shui-Zhong Luo, Jian-Ping Luo, Zhi Zheng, Shao-Tong Jiang, Yan-Yan Zhao, Xi-Yang Zhong.  (2022)  Preparation and characteristics of sucrose-resistant emulsions and their application in soft candies with low sugar and high lutein contents and strong antioxidant activity.  FOOD HYDROCOLLOIDS,      [PMID:] [10.1016/j.foodhyd.2022.107619]
9. Jiang Hong, Fan Yahui, Li Juan, Wang Jiaqi, Kong Liyun, Wang Lina, Li Zhaofang, Ma Mei, Shi Xin, Liu Sijiao, Shi Jia, Zhu Hailu, Liu XiaoHong, Ma Le.  (2022)  The Associations of Plasma Carotenoids and Vitamins With Risk of Age-Related Macular Degeneration: Results From a Matched Case-Control Study in China and Meta-Analysis.  Frontiers in Nutrition,      [PMID:35223939] [10.3389/fnut.2022.745390]
10. Chengchen Cai, Ming Zhang, Haiming Chen, Wenxue Chen, Weijun Chen, Qiuping Zhong.  (2022)  Enhancement of norisoprenoid and acetoin production for improving the aroma of fermented mango juice by Bacillus subtilis-HNU-B3.  PROCESS BIOCHEMISTRY,      [PMID:] [10.1016/j.procbio.2022.01.002]
11. Hai-Feng Jiang, Cheng Chen, Xin-Yuan Jiang, Jing-Lei Shen, Fei Ling, Peng-Fei Li, Gao-Xue Wang.  (2021)  Luteolin in Lonicera japonica inhibits the proliferation of white spot syndrome virus in the crayfish Procambarus clarkii.  AQUACULTURE,      [PMID:] [10.1016/j.aquaculture.2021.737852]
12. Zhipeng Qi, Xianyu Fan, Chunyi Zhu, Dongsheng Chang, Jianjun Pei, Linguo Zhao.  (2021)  Overexpression and Characterization of a Novel Plant Carotenoid Cleavage Dioxygenase 1 from Morus notabilis.  CHEMISTRY & BIODIVERSITY,  19  (2): (e202100735).  [PMID:34821468] [10.1002/cbdv.202100735]
13. Dang Qingyuan, Sha Haiyun, Nie Jiyun, Wang Yongzhang, Yuan Yongbing, Jia Dongjie.  (2021)  An apple (Malus domestica) AP2/ERF transcription factor modulates carotenoid accumulation.  Horticulture Research,      [PMID:34611138] [10.1038/s41438-021-00694-w]
14. Fei-Fei Qi, Tian-You Ma, Ya-Meng Fan, Lan-ling Chu, Yan Liu, Yan Yu.  (2020)  Nanoparticle-based polyacrylonitrile monolithic column for highly efficient micro solid-phase extraction of carotenoids and vitamins in human serum.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:33278673] [10.1016/j.chroma.2020.461755]
15. Zhenghan Shi, Yanli Lu, Zetao Chen, Chen Cheng, Jie Xu, Qingqing Zhang, Zupeng Yan, Zisheng Luo, Qingjun Liu.  (2020)  Electrochemical non-enzymatic sensing of glycoside toxins by boronic acid functionalized nano-composites on screen-printed electrode.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2020.129197]
16. Huijuan Shangguan, Shan Zhang, Xin Li, Qi Zhou, Jie Shi, Qianchun Deng, Fenghong Huang.  (2020)  Synthesis of lutein esters using a novel biocatalyst of Candida antarctica lipase B covalently immobilized on functionalized graphitic carbon nitride nanosheets.  RSC Advances,  10  (15): (8949-8957).  [PMID:35496558] [10.1039/D0RA00563K]
17. Lei Wang, Yujie Li, Dong Xiang, Weimin Zhang, Xinpeng Bai.  (2020)  Stability of lutein in O/W emulsion prepared using xanthan and propylene glycol alginate.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:32084481] [10.1016/j.ijbiomac.2020.02.162]
18. Jia Dongjie, Li Yuchen, Jia Kun, Huang Benchang, Dang Qingyuan, Wang Huimin, Wang Xinyuan, Li Chunyu, Zhang Yugang, Nie Jiyun, Yuan Yongbing.  (2024)  Abscisic acid activates transcription factor module MdABI5–MdMYBS1 during carotenoid-derived apple fruit coloration.  PLANT PHYSIOLOGY,      [PMID:38536032] [10.1093/plphys/kiae188]
19. Shan Zhang, Zhida Sun, David Julian McClements, Bijun Xie, Ruofan Zheng, Qianchun Deng, Yashu Chen.  (2024)  Carotenoids encapsulated in natural flaxseed oil body: Different colloidal interfaces induce their behavior and stability disparity.  FOOD HYDROCOLLOIDS,      [PMID:] [10.1016/j.foodhyd.2024.110311]
20. Zi-Ling Li, Xiao-Run Qi, Yi-Heng Xu, Jia-Qi Zhao, Gui-Fu Zuo, Man-Man Wang.  (2025)  Highly efficient and convenient QuEChERS using ZIF-67 derived magnetic nanoporous carbon for determination of carbamate pesticides in various vegetable and fruit samples.  FOOD CHEMISTRY,      [PMID:39848044] [10.1016/j.foodchem.2025.142904]
21. Qiu Fu, Ying Qin, Xinjia Zhang, Lijian Sun, Jiang Chang.  (2024)  Highly transparent, low haze and ultraviolet to blue light blocking cellulose films tailored by lutein as electronic screen protectors.  INDUSTRIAL CROPS AND PRODUCTS,      [PMID:] [10.1016/j.indcrop.2024.118897]
22. Kaixuan Ke, Ling Guo, Zhipeng Qi, Dou Dou, Han Ma, Xianying Fang, Linguo Zhao.  (2024)  Molecular cloning, expression, and biochemical characterization of carotenoid cleavage dioxygenase 1 (LbCCD1) from Lycium barbarum.  Molecular Catalysis,      [PMID:] [10.1016/j.mcat.2024.114561]
23. Weiwei Cheng, Jiahe Xu, Xiaowen Wang, Xinyang Li, Yufeng Chen, Guoqin Liu, Xuxia Zhou, Yuting Ding, Shulai Liu.  (2024)  Multiple Mechanisms of Haematococcus pluvialis–Derived Carotenoids to Inhibit Glycidyl Ester Formation in Rice Oil and a Chemical Model at High Temperatures.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:39140411] [10.1021/acs.jafc.4c04019]
24. Yuxiang Wang, Benguo Liu, Yuling Ma, Chunyan Wang, Hanjun Ma, Sheng Geng.  (2024)  Oil/water interface behavior of hesperidin methylchalcone and its application in nano-emulsions.  FOOD CHEMISTRY,      [PMID:39276552] [10.1016/j.foodchem.2024.141235]
25. Xuening Song, Yingting Luo, Wenduo Zhao, Simiao Liu, Yuzhuo Wang, Hao Zhang.  (2024)  Preparation and Characterization of Lutein Co-Amorphous Formulation with Enhanced Solubility and Dissolution.  Foods,  13  (13): (2029).  [PMID:38998535] [10.3390/foods13132029]
26. Jingwen Yu, Xiangwei Xiao, Baiying Chen, Zeyuan Deng, Xuan Chen, Yawei Fan, Hongyan Li.  (2024)  Synergistic and Antagonistic Activity of Selected Dietary Phytochemicals against Oxidative Stress-Induced Injury in Cardiac H9c2 Cells via the Nrf2 Signaling Pathway.  Foods,  13  (15): (2440).  [PMID:39123631] [10.3390/foods13152440]
27. Yves Harimana, Bertrand Muhoza, Philip Munyandamutsa, Javzan Gankhuyag, Shuang Zhang, Yang Li.  (2024)  Unraveling the binding mechanism between soybean protein isolate and selected bioactive compounds.  FOOD CHEMISTRY,      [PMID:38513491] [10.1016/j.foodchem.2024.139031]
28. Jiayi Zhang, Jingzhi Wang, Junfeng Wang, Weifeng Ni, Shichao Liu, Daqing Zhao, Zhengqi Dong, Shiting Yu, Siming Wang, Weinan Wang, Meichen Liu.  (2025)  Integrated multi-omics and machine learning reveal the intrinsic relationship between color and flavor variations in processed ginseng products through major pigment dynamics and non-enzymatic pathways.  LWT-FOOD SCIENCE AND TECHNOLOGY,      [PMID:] [10.1016/j.lwt.2025.118161]
29. Xuan Chen, Liufeng Zheng, Bing Zhang, Zeyuan Deng, Hongyan Li.  (2022)  Synergistic protection of quercetin and lycopene against oxidative stress via SIRT1-Nox4-ROS axis in HUVEC cells.  Current Research in Food Science,      [PMID:36304485] [10.1016/j.crfs.2022.10.018]
30. Zi-Ling Li, Da-Jin Yang, Jia-Qi Zhao, Wen-Jie Sun, Jie Gao, Shu-Feng Song, Hou-Jun Xu, Hai-Jie Li, Fa-Ming Tian, Man-Man Wang.  (2025)  Fabrication and application of ferrocene contained MOF derived porous carbon: A single multi-interference clean-up QuEChERS sorbent for facile analysis of triazine herbicides in various fruits and vegetables by LC-MS/MS.  FOOD CHEMISTRY,      [PMID:40252445] [10.1016/j.foodchem.2025.144351]
31. Beixiao Zhang, Gul Muhammad, Liya Deng, Md Asraful Alam, Anqi Zhao, Thomas O. Butler, Zhenglong Li, Ximing Zhang, Jingliang Xu.  (2025)  A sustainable and efficient method for sequential extraction of lutein and lipid from deep eutectic solvent pretreated Chlorella pyrenoidosa.  RSC Advances,  15  (18): (14072-14078).  [PMID:40309118] [10.1039/D5RA00423C]
32. Lanxin Zhang, Shengnan Wang, Xinhong Liu, Jun Li, Rui Wang, He Liu.  (2025)  Lutein liposomes for enhancing lutein delivery stabilized by stigmasterol: Preparation, characterization and release in vitro.  JOURNAL OF FOOD ENGINEERING,      [PMID:] [10.1016/j.jfoodeng.2025.112691]
33. Shuo Zhang, Shuang Guo, Jiayu Han, Zhaolian Han, Hailing Yu, Xue Zhang, Ningcan Ma, Zhiqiang Cheng.  (2025)  Production of cellulose nanocrystals from waste Phellinus igniarius substrate by enzymatic hydrolysis-centrifugal fractionation method: Construction of a bioactive substance delivery system.  FOOD RESEARCH INTERNATIONAL,      [PMID:41267321] [10.1016/j.foodres.2025.117763]
34. Mengting Cui, Qingpeng Gao, Jinling Bai, Mengting Fu, Zhiyu Liu, Zhixin Ouyang, Liyun Kong, Le Ma.  (2025)  A Rapid and Sensitive Method for the Determination of Vitamin E and Carotenoids in Vegetables and Fruits Using Deep Eutectic Solvent-Based Dispersive Liquid-Liquid Microextraction.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:41478027] [10.1016/j.chroma.2025.466656]
35. Si Chen, Mengmeng Wei, Guoyang Liu, Benguo Liu.  (2025)  Construction and Characterization of Emulsions Stabilized by Whey Protein Isolate-Naringin-Sodium Alginate Ternary Complex.  Foods,  15  (1):   [PMID:41517085] [10.3390/foods15010019]
Solution Calculators
Reviews

Customer Reviews

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.