≥98% pour les flux de travail chromatographiques et analytiques sensibles nécessitant une interférence de ligne de base minimale.
Protected from light,Store at -80°C Expédition Dry ice packs + Cold packs. Consultez le COA spécifique au lot pour les spécifications exactes.
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Cité dans 0 publications à comité de lecture couvrant la chromatographie, la synthèse organique et les réactions de couplage croisé.
12-Ethyl-9-hydroxycamptothecin is a derivative of Camptothecin. Camptothecin (CPT), a kind of alkaloid, is a DNA topoisomerase I (Topo I) inhibitor with an IC 50 of 679 nM.
In Vitro
12-Ethyl-9-hydroxycamptothecin is a derivative of Camptothecin. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Form:Solid
Document complet couvrant les dangers, la manipulation, le stockage et la conformité réglementaire.
<<<<<<< HEAD Télécharger la SDS → ======= Télécharger la SDS → >>>>>>> release248-p3Données qualité spécifiques au lot. Saisissez votre numéro de lot pour récupérer le COA exact.
Rechercher le COA →Résumé de référence rapide des spécifications et applications du produit.
Voir la fiche technique →Attributs de qualité complets et critères d'acceptation pour cette qualité.
Voir la fiche de spécifications →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Alkaloids and derivatives |
| Classe | Camptothecins |
| Subclass | Not available |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Camptothecins |
| Alternative Parents | Terpene lactones Sesquiterpenoids Pyranoindolizines Quinolines and derivatives Pyranopyridines Polyhalopyridines N-acylpyrrolidines Methylpyridines Hydroxypyridines Fatty acid esters Dihydropyridines Dihydropyranones 1-hydroxy-2-unsubstituted benzenoids N-acyl amines Tertiary carboxylic acid amides Tertiary alcohols Secondary ketimines Heteroaromatic compounds Lactones Lactams Carboxylic acid esters Propargyl-type 1,3-dipolar organic compounds Oxacyclic compounds Monocarboxylic acids and derivatives Azacyclic compounds Organopnictogen compounds Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Camptothecin - Terpene lactone - Farsesane sesquiterpenoid - Sesquiterpenoid - Pyranoindolizine - Quinoline - Pyranopyridine - Pyrrolopyridine - Indolizine - Polyhalopyridine - N-acylpyrrolidine - 1-hydroxy-2-unsubstituted benzenoid - Methylpyridine - Hydroxypyridine - Fatty acid ester - Dihydropyridine - Dihydropyranone - Fatty acyl - Benzenoid - Pyridine - Pyran - N-acyl-amine - Heteroaromatic compound - Tertiary carboxylic acid amide - Tertiary alcohol - Secondary ketimine - Pyrrolidine - Lactone - Lactam - Ketimine - Carboxylic acid ester - Carboxamide group - Oxacycle - Azacycle - Organoheterocyclic compound - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Monocarboxylic acid or derivatives - Carboxylic acid derivative - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Imine - Alcohol - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as camptothecins. These are heterocyclic compounds comprising a planar pentacyclic ring structure, that includes a pyrrolo[3,4-beta]-quinoline moiety (rings A, B and C), conjugated pyridone moiety (ring D) and one chiral center at position 20 within the alpha-hydroxy lactone ring with (S) configuration (the E-ring). |
| External Descriptors | Not available |
| Solubilité | DMSO : 83.33 mg/mL (212.36 mM; Need ultrasonic) |
|---|---|
| Poids moléculaire | 392.400 g/mol |
| XLogP3 | 1.400 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 2 |
| Exact Mass | 392.137 Da |
| Monoisotopic Mass | 392.137 Da |
| Topological Polar Surface Area | 100.000 Ų |
| Heavy Atom Count | 29 |
| Formal Charge | 0 |
| Complexity | 820.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 1 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
