3,3'-Dithiodipropionic acid - ≥97% , CAS No.1119-62-6

CAS: 1119-62-6 Cat. No.: D305354 Molecular Weight: 210.27 Beilstein Registry Number: 1778543 EC Number: 214-284-0
AVAILABLE TO ORDER
GRADE & PURITY ≥97%
Synonyms
DTDPA | 3,3'-Dithiodipropionic acid | 3,3-Dithiodipropionic acid | 4XKL2JJ08I | 3,3'-Dithiodipropanoic acid | BP-31240 | Propionic acid,3'-dithiodi- | 3,3'-Dithiobis(dipropionic acid) | 3,3'-Dithiobispropionic acid | MFCD00002780 | A851262 | Bis(2-carboxy
Storage
Room temperature
Shipped In
Normal
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
100g
D305354-100g
5
$14.90
500g
D305354-500g
2
$48.90
Enter a quantity for the sizes you want to add.
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Why this grade

≥97% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Room temperature Ships Normal Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 93 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

3,3′-Dithiodipropionic acid forms monolayers on a polycrystalline gold electrode through a self-assembly procedure to form gold 3,3′-dithiodipropionic acid self-assembled monolayer modified electrode. It is the precursor substrate in the synthesis of 3-mercaptopropionic acid-containing polythioesters. It is added as primary carbon supplement in the culture medium of novel betaproteobacterium, strain DPN7.
3,3′-Dithiodipropionic acid was used as capping agent for introducing charge on gold nanoparticles surfaces.

Specifications

Synonyms
DTDPA | 3, 3'-Dithiodipropionic acid | 3, 3-Dithiodipropionic acid | 4XKL2JJ08I | 3, 3'-Dithiodipropanoic acid | BP-31240 | Propionic acid, 3'-dithiodi- | 3, 3'-Dithiobis(dipropionic acid) | 3, 3'-Dithiobispropionic acid | MFCD00002780 | A851262 | Bis(2-carboxy
Specifications & Purity
≥97%
Storage
Room temperature
Shipped In
Normal
Purity
≥97%
Names and Identifiers
Pubchem Sid504756253
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504756253
Canonical SmilesC(CSSCCC(=O)O)C(=O)O
IUPAC Name3-(2-carboxyethyldisulfanyl)propanoic acid
InChIKeyYCLSOMLVSHPPFV-UHFFFAOYSA-N
INCHI1S/C6H10O4S2/c7-5(8)1-3-11-12-4-2-6(9)10/h1-4H2,(H,7,8)(H,9,10)
Isomeric SMILES C(CSSCCC(=O)O)C(=O)O
WGK Germany 3
Molecular Weight 210.27
Beilstein 1778543
Reaxy-Rn 1778543
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1778543&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

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✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

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Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic acids and derivatives
ClassCarboxylic acids and derivatives
SubclassDicarboxylic acids and derivatives
Intermediate Tree Nodes Not available
Direct ParentDicarboxylic acids and derivatives
Alternative Parents Dialkyldisulfides  Sulfenyl compounds  Carboxylic acids  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAliphatic acyclic compounds
Substituents Dicarboxylic acid or derivatives - Dialkyldisulfide - Organic disulfide - Sulfenyl compound - Carboxylic acid - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organosulfur compound - Organooxygen compound - Carbonyl group - Aliphatic acyclic compound
DescriptionThis compound belongs to the class of organic compounds known as dicarboxylic acids and derivatives. These are organic compounds containing exactly two carboxylic acid groups.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
TSHR Tclin Thyroid stimulating hormone receptor (29986 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Human immunodeficiency virus 1 (70413 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

9 results found

Lot NumberCertificate TypeDateItem
K2514823Certificate of AnalysisNov 21, 2025 D305354
K2519742Certificate of AnalysisNov 21, 2025 D305354
K2519745Certificate of AnalysisNov 21, 2025 D305354
C2127354Certificate of AnalysisJan 15, 2025 D305354
C2304471Certificate of AnalysisMar 14, 2023 D305354
C2304472Certificate of AnalysisMar 14, 2023 D305354
C2304482Certificate of AnalysisMar 14, 2023 D305354
K2513713Certificate of AnalysisMar 14, 2023 D305354
H2223049Certificate of AnalysisAug 27, 2022 D305354
Chemical and Physical Properties
SolubilityInsoluble in water, soluble in methanol
Melt Point(°C)155-158°C
Molecular Weight210.300 g/mol
XLogP3-0.100
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count7
Exact Mass210.002 Da
Monoisotopic Mass210.002 Da
Topological Polar Surface Area125.000 Ų
Heavy Atom Count12
Formal Charge0
Complexity142.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
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65. Ying Zhao, Changhao Jia, Zhixin Yao, Gang Chen, Gui Huang, Hui Li, Linghong Lu, Taiwei Jin, Yan Tang, Zengyan Zhu, Xuenong Zhang.  (2024)  Dexamethasone Pretreatment Potentiates a Folic Acid-Functionalized Delivery System for Enhanced Lung Cancer Therapy.  MOLECULAR PHARMACEUTICS,      [PMID:38346386] [10.1021/acs.molpharmaceut.3c00472]
66. Huiping Zhang, Liang Li, Wei Li, Hongxia Yin, Huiyun Wang, Xue Ke.  (2024)  Endosomal pH, Redox Dual-Sensitive Prodrug Micelles Based on Hyaluronic Acid for Intracellular Camptothecin Delivery and Active Tumor Targeting in Cancer Therapy.  Pharmaceutics,  16  (10): (1327).  [PMID:39458656] [10.3390/pharmaceutics16101327]
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90. Saichao Wei, Haitao Zhang, Zhou Fang, Jiawang Shi, Baoying Li, Zhenjing Liu, Yahui Song, Jiaqi Xu, Qian Yu, Min Zhang, Kehai Liu.  (2026)  Copper complexes mediate the in situ production of reactive oxygen species in the nucleus, enhancing the anti-tumor efficacy of PTX.  Results in Engineering,      [PMID:] [10.1016/j.rineng.2026.109429]
91. Na Yao, Lian Deng, Ziqing Weng, Yang Song, Ning Lei, Junda Liu, Neng Qiu.  (2026)  Inclusion complex of biotinylated podophyllotoxin with hydroxypropyl-β-cyclodextrin: enhanced solubility, tumor selectivity and efficacy.  JOURNAL OF MOLECULAR STRUCTURE,      [PMID:] [10.1016/j.molstruc.2026.145666]
92. Yahui Wu, Zhipu Liu, Yi Zhang, Senfeng Zhao, Miaoqing Li, Ruiyang Zhang, Jiahui Cao, Peng Liu, Liming Song, Yin Liu, Yunpeng Zhai, Weijie Wang, Ruopeng Liang, Rongtao Zhu, Yupeng Shi, Yuling Sun.  (2026)  Multistimuli-responsive degradable metal-organic framework nanoplatform potentiates photoimmunotherapy for hepatocellular carcinoma via cGAS-STING pathway activation.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2026.174217]
93. Jianguo Feng, Zhen Li, Zhiyang Chen, Tianzhen Jiang, Xiang Li, Ziyi Wu.  (2026)  Enzyme and redox responsive mesoporous silica nanoparticles: Enhancing the insecticidal efficacy and biosafety of indoxacarb.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,      [PMID:] [10.1016/j.colsurfa.2026.140160]
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