4-Aminobenzohydrazide - 10mM in DMSO , CAS No.5351-17-7

CAS: 5351-17-7 Cat. No.: A424573 Formule: C₇H₉N₃O Poids moléculaire: 151.17 Beilstein Registry Number: 14(3)1081 Numéro CE: 226-324-4

QUALITÉ & PURETÉ 10mM in DMSO

Synonyms

4-Aminobenzohydrazide|5351-17-7|4-Aminobenzhydrazide|4-Aminobenzoic acid hydrazide|Amben hydrazide|p-Aminobenzhydrazide|Aminostimil|p-Aminobenzoic acid hydrazide|4-Aminobenzoylhydrazine|Benzoic acid, 4-amino-, hydrazide|p-Aminobenzoyl hydrazide|p-Aminoben

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Spécifications

Synonymes

4-Aminobenzohydrazide | 5351-17-7 | 4-Aminobenzhydrazide | 4-Aminobenzoic acid hydrazide | Amben hydrazide | p-Aminobenzhydrazide | Aminostimil | p-Aminobenzoic acid hydrazide | 4-Aminobenzoylhydrazine | Benzoic acid, 4-amino-, hydrazide | p-Aminobenzoyl hydrazide | p-Aminoben

Spécifications et pureté

10mM in DMSO

Mécanismes biochimiques et physiologiques

Potent, irreversible and specific MPO inhibitor (IC 50 = 300 nM). Benzoic acid analog. No inhibition of catalase or glutathione peroxidase activity. Inhibits apoptosis in vitro .

Conditions de stockage de stockage

Store at -80°C

Expédié en

Dry ice packs + Cold packs

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Type d'action

INHIBITOR

Noms et identifiants

Pubchem Sid

528760277

Sourires canoniques

C1=CC(=CC=C1C(=O)NN)N

IUPAC Name

4-aminobenzohydrazide

InChIKey

WPBZMCGPFHZRHJ-UHFFFAOYSA-N

INCHI

1S/C7H9N3O/c8-6-3-1-5(2-4-6)7(11)10-9/h1-4H,8-9H2,(H,10,11)

Isomères SMILES

C1=CC(=CC=C1C(=O)NN)N

WGK Allemagne

3

RTECS

DG2580000

Poids moléculaire

151.17

Beilstein

14(3)1081

Reaxy-Rn

639053

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=639053&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Classe Benzene and substituted derivatives
      • Subclass Benzoic acids and derivatives

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Classe: Benzene and substituted derivatives
• Subclass: Benzoic acids and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Aminobenzoic acids and derivatives
• Alternative Parents: Benzoyl derivatives Aniline and substituted anilines Carboxylic acid hydrazides Amino acids and derivatives Primary amines Organopnictogen compounds Organooxygen compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Aminobenzoic acid or derivatives - Benzoyl - Aniline or substituted anilines - Amino acid or derivatives - Carboxylic acid hydrazide - Carboxylic acid derivative - Amine - Primary amine - Organooxygen compound - Organonitrogen compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic oxygen compound - Organic nitrogen compound - Aromatic homomonocyclic compound
• Description: This compound belongs to the class of organic compounds known as aminobenzoic acids and derivatives. These are benzoic acids (or derivative thereof) containing an amine group attached to the benzene moiety.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Cibles associées (humaines)

MPO Tchem Myeloperoxidase (2 Activities)

Discover Target: MPO

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MPO Tchem Myeloperoxidase (1002 Activities)

Discover Target: MPO

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Cibles associées (non humaines)

Mycobacterium tuberculosis (203094 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mécanismes d'action

Propriétés chimiques et physiques

• Sensibilité: air sensitive
• Point de fusion (°C): 228 °C
• Poids moléculaire: 151.170 g/mol
• XLogP3: -0.700
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 151.075 Da
• Monoisotopic Mass: 151.075 Da
• Topological Polar Surface Area: 81.100 Ų
• Heavy Atom Count: 11
• Formal Charge: 0
• Complexity: 141.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1