8-Bromo-cAMP - 10mM in DMSO , CAS No.76939-46-3

CAS: 76939-46-3 Cat. No.: B407933 Molecular Weight: 430.08

GRADE & PURITY 10mM in DMSO

Synonyms

8-Br-Camp | 8-bromoadenosine 3',5'-cyclic monophosphate sodium salt

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Information

8-Bromo-cAMP 8-bromo-cAMP (8-Br-Camp) is a cell permeable analog of cAMP that activates cyclic-AMP-dependent protein kinase with a Ka value of 0.05 μM; and a PKA activator.
In vitro

8-Bromo-cAMP improves the reprogramming efficiency of human neonatal foreskin fibroblast (HFF1) cells. In bronchial epithelial cells, 8-Bromo-cAMP decreases HDE-stimulated tumor necrosis factor (TNF)-α-converting enzyme (TACE; ADAM-17) activity and subsequent TNF-α release.

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

Synonyms

8-Br-Camp | 8-bromoadenosine 3', 5'-cyclic monophosphate sodium salt

Specifications & Purity

10mM in DMSO

Biochemical and Physiological Mechanisms

8-bromo-cAMP (8-Br-Camp) is a cell permeable analog of cAMP that activates cyclic-AMP-dependent protein kinase with a Ka value of 0.05 μM; and a PKA activator.

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

• Isomeric SMILES: C1[C@@H]2[C@H]([C@H]([C@@H](O2)N3C4=NC=NC(=C4N=C3Br)N)O)OP(=O)(O1)[O-].[Na+]
• Molecular Weight: 430.08
• Reaxy-Rn: 26039674
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=26039674&ln=